[PDF] Top 20 Genotyping and drug resistance patterns of Mycobacterium tuberculosis strains observed in a tuberculosis high-burden
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Genotyping and drug resistance patterns of Mycobacterium tuberculosis strains observed in a tuberculosis high-burden
... total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in ...Fortaleza. Drug susceptibility and ... See full document
8
Drug Resistance and Genotypes of Strains of Mycobacterium tuberculosis Isolated from Human Immunodeficiency Virus- infected and Non-infected Tuberculosis Patients in Bauru, São Paulo, Brazil
... 42.7% in 1992 (Silva et al. 1992); another survey determined primary resistance in that state during the nineties to be ...16.5% and secondary resistance between ...47.5% and ... See full document
6
Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action
... CPZ and TZ had similar activity against strains susceptible to isoniazid (INH) and rifampicin (RIF) as well as to strains resistant to these antibiotics and as many as five other ...The ... See full document
14
Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium
... number of compounds have been shown as potential inhibitors of the ...M. tuberculosis efflux systems (Viveiros et ...thioridazine and chlorpromazine and the phenylalkylamine verapamil ... See full document
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Clinical data and molecular analysis of Mycobacterium tuberculosis isolates from drug-resistant tuberculosis patients in Goiás, Brazil
... evolution of drug resistance patterns observed in the ...M. tuberculosis isolates from patients 4 and 8 was unexpected, as it went from an MDR to a monoresis- tance ... See full document
7
Detection of tuberculosis drug resistance a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype MTBDRplus
... detect drug-resistant TB and MDR-TB showed similar accuracy to Genotype®MTBDRplus, with the advantage of being easily optimised on a routine basis to address accurately the early detection of ... See full document
8
Plasmidbased controls to detect rpoB mutations in Mycobacterium tuberculosis by quantitative polymerase chain reactionhighresolution melting
... to drug resistance in Mycobacterium ...C526T and C531T mutations in the rifampicin resistance-determining region (RRDR) of the rpoB gene with qPCR-HRM using ... See full document
4
The forest behind the tree: phylogenetic exploration of a dominant Mycobacterium tuberculosis strain lineage from a high tuberculosis burden country.
... discrimination and tracing at the strain level, molecular epidemiological markers can also serve to predict genetic lineages, which is useful both for TB control and ...use of MIRU-VNTR typing or ... See full document
10
First evaluation of drug-resistant Mycobacterium tuberculosis clinical isolates from Congo revealed misdetection of fluoroquinolone resistance by line probe assay due to a double substitution T80A-A90G in GyrA.
... (ofloxacin and moxifloxacin) and injectable second-line drug (amikacin), and by genotypic MTBDRsl ...MDR strains were susceptible to amikacin and fluoroquinolones thus excluding ... See full document
6
Spoligotyping of clinical Mycobacterium tuberculosis isolates from the state of Minas Gerais, Brazil
... we observed a high rate of cluster- ing (77/114, ...bulk of TB strains in our location (92/114, ...evolutionary strains that belong to the principal genetic groups ... See full document
7
Genome Analysis of the First Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis in Malaysia Provides Insights into the Genetic Basis of Its Biology and Drug Resistance.
... origin and nature of the XDR M. tuberculosis strains remain ...occurrence and transmission of XDR-TB ...expansion and spreading of one strain harboring several ... See full document
20
The rationale for using rifabutin in the treatment of MDR and XDR tuberculosis outbreaks.
... collection of 342 M(X)DR M. tuberculosis clinical isolates obtained from patients resident in the ECP, South Africa, 217 (63%) were previously characterised as members of the atypical Beijing ... See full document
4
Genotyping and drug resistance patterns of Mycobacterium tuberculosis strains observed in a tuberculosis highburden municipality in Northeast, Brazil
... total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in ...Fortaleza. Drug susceptibility and ... See full document
8
Anti-Tuberculosis Drug Resistance in Strains of Mycobacterium tuberculosis Isolated from Patients in a Tertiary Hospital in Bahia
... frequent in the group with no resistance compared to the group with resistance, and an inverse association with global resistance was found in the univariate analysis that ... See full document
8
Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola
... selection of the studied sample of M. tuberculosis clinical isolates and, main results from drug susceptibility testing and ...contaminated and another 5 showed no growth, ... See full document
10
High throughput phenotypic analysis of Mycobacterium tuberculosis and Mycobacterium bovis strains' metabolism using biolog phenotype microarrays.
... PM9 and PM10 plates. Though they did not characterize strains, they divided the ...M. tuberculosis complex into two groups based on their salt-tolerance in some ...[33,34] and possibly ... See full document
15
Comparison of three molecular typing methods to assess genetic diversity for Mycobacterium tuberculosis
... all strains (aroE, ddl, dnaN, fumC, pta, purA, purH, recA, rpoB, ...described in the methodology, the seven best were chosen to be used in the MLST scheme, namely gyrA, gyrB, katG, purA, recA, rpoB, ... See full document
7
A complex scenario of tuberculosis transmission is revealed through genetic and epidemiological surveys in Porto
... decrease of TB ...changes in condi- ...control in urban areas, a full monitoring of TB transmission patterns is required to improve control strategies, including a detailed and ... See full document
12
Epidemiology of Peripheral Lymph Node Tuberculosis and Genotyping of M. tuberculosis Strains: A Case-Control Study.
... epidemic of tuberculosis (TB) remains a major health problem ...cause of death from an infectious disease after the human immunodeficiency virus (HIV) ...[1]. In 2011, there were 8.7 million ... See full document
10
Characterization of the genetic diversity of Mycobacterium tuberculosis in São Paulo city, Brazil
... used in the molecular epi- demiology of TB, to investigate the population structure of ...M. tuberculosis, focusing on the identification of genotypic lineages and spoligotype ... See full document
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