[PDF] Top 20 GSTT1 null genotype contributes to lung cancer risk in asian populations: a meta-analysis of 23 studies.

... used to measure the strength of association of GSTT1 null genotype with lung cancer ...ORs of GSTT1 null genotype mentioned above was ... See full document

... limitations in this meta-analysis. First of all, even though we performed subgroup analyses stratified by ethnicity and control source, the heterogeneity for GSTM1 polymorphism among the ... See full document

... and GSTT1 null polymorphism is a risk factor for developing hepatocellular ...the meta-analysis was restricted to larger studies, suggesting potential small studies ... See full document

... aggressiveness of cells in normal or hyperplastic epithelial cells ...Accumulation of DNA damage and lack of response to genotoxic stress contribute to an earlier step in ... See full document

... according to ethnicity, a significantly increased risks were identified among Asians and Caucasians for the 2 exon 7 genotype variants, however no significant association was found in mixed ... See full document

... including lung tissue and overexpress in cisplatin- resistant cell lines, encodes an enzyme—cleft lip and palate trans- membrane 1-like that may be associated with apoptosis ...[13]. In consideration ... See full document

... exposure to fluoride in drinking water, the effect of fluoride on hip fracture risk is an important public health ...Fluoride in drinking water derives from natural sources or is added ... See full document

... 405V in longevity, which was not confirmed in other ...Chinese studies indicated a higher MAF of CETP 405V in the control group than other ethnicities, and this was also supported by ... See full document

... results of the NPC trial and sixteen observational studies suggest that moderate but not very high selenium levels may reduce risk of lung ...cancer. In the NPC trial, ... See full document

... Most studies concerning the effects of PCI on NCF and QOL were conducted in patients with SCLC; and relevant data in patients with NSCLC are limited, mainly due to the lack of ... See full document

... Mechanisms of action of metformin and preclinical and ongoing studies in hematologic ...mechanisms of metformin have been proposed (Figure ...resulting in low ATP production and ... See full document

... end of the VDR gene. It does not appear to change the nature of the translated VDR protein ...linked in a haplotype with the variable-length poly A sequence within the 3 9- untranslated ... See full document

... ficação da seqüência do DNA de interesse foi obtida por 35 ciclos que compreenderam etapas de desnaturação do DNA a 94ºC por 2 minutos, anelamento das seqüências iniciadoras da reação (primers) a 59ºC por 1 minuto e ex- ... See full document

... measure of association across studies. Because the absolute risk of ovarian cancer is low in human, the ORs in case–control studies should approximate the RRs or ... See full document

... appeared in more than one database or from more than one set of search terms) (Figure ...relevance. Of these 91, 75 studies were excluded as follows: the studies did not reported the ... See full document

... The analysis of the genotype distribution of GSTM1, GSTT1, and GSTP1 Ile105Val polymor- phisms showed that the case and control popula- tions were homogeneous with respect to ... See full document

... effect of familial aggregation cancers suggest that common susceptibility genes may act to increase the risk of lung ...stratified analysis suggested evidence of an ... See full document

... Differences in use of anticoagulants by some or all of the participants in individual studies could further contribute to heterogeneity in the ...use in study ... See full document

... aware of the artificial boundaries between surgery and ...possibilities. To approach any malignancy with curative intent, one must be aware of these ...borders of pride and enthusiasm over ... See full document

... prostate cancer susceptibility was measured by odds ratios (ORs) and 95% confidence intervals (CIs) under five genetic models: allele model (mutant [M] allele versus wild [W] allele), dominant model (WM+MM versus ... See full document