[PDF] Top 20 Hippocampal proteomic profile in temporal lobe epilepsy

... protein profile of human epileptic hippocampi (N=6) and control hippocampi obtained from autopsy ...increased in the hippocampus of patients with TLE were: isoform 1 of serum albumin, HSP 70, ... See full document

... hubs in both ...detected in fetal brain [28] and in central nervous system tumors [29], being probably active in controlling neural differentiation ...genes in human CA3 ... See full document

... left hippocampal sclerosis on MRI. In two patients, in all seizures in which ictal spitting was observed, EEG seizure onset was seen in the left temporal ...lobe. ... See full document

... JME in relation to the circadian rhythm, this has significance in directing the clin- ical treatment of patients, given the evidence of close rela- tionship between sleep and ...be in place, as ... See full document

... of hippocampal sclerosis could be identified in this series from the analysis of z-scores: no MTS, neuronal cell loss within the first standard deviation compared to controls (Z-score <2 in each ... See full document

... classified in three groups: (A) those who had an active work based on monthly income (formal or no-formal employment); (B) those unemployed, receiving ill-health benefits or retired, individuals who were ... See full document

... Several studies have reported T2 signal abnormalities, suggesting that the signal cor- relates with gliosis and may not be directly related to the degree of neuronal loss (6,7,14,16). However, all of these studies ... See full document

... the hippocampal lesion may explain the development of re f r a c t o ry epilepsy, many questions re g a rding clinicopathological relationships rise fro m this case: Do the cyst contributed to the ... See full document

... 512) in the coronal planes perpendicular to the long axis of hip- pocampus, including the totality of the temporal lobe; fast field echo (FFE) T1-weighted (TR=30 milliseconds, ...512, in the ... See full document

... lobo temporal (ELT) é o tipo de epilepsia parcial mais comum e a esclerose hipocampal (EH) o substrato neuropatológico mais freqüentemente encontrado em pacientes com epilepsia ... See full document

... activity in hippocampal CA1 neurons, we tested rosiglitazone on synaptic transmission of CA1-Schaffer collateral ...machinery in structure and function were found in mice after ... See full document

... outcomes in 205 patients with medically intractable mesial temporal lobe epilepsy (MTLE) with unilateral hippocampal sclerosis ...higher in patients with poor outcome. In ... See full document

... observed in patients with ...performance in patients with refractory mesial temporal lobe epilepsy with hippocampal sclerosis ...higher in MTLE-HS patients than controls, ... See full document

... All patients completed an extensive preoperative evaluation, which included high-resolution MRI and prolonged noninvasive video-EEG recording. Visual inspection of the MRI images revealed that all patients had clear ... See full document

... spatial profile and consistency (stereopy) of the ‘escaping’ ...located in the ipsilateral temporal lobe and sub- cortical areas were involved in agreement with experimental / clinical ... See full document

... generated in mesial tem- poral lobe structures simultaneously with depth electrodes implanted in these structures, if anatomical volume involved is large enough, for instance, in the case of ... See full document

... examine temporal pole (TP) signal and quantitative changes in temporal lobe epilepsy (TLE) patients with hippocampal sclerosis (HS) using coronal fluid-attenuated ... See full document

... of epilepsy onset; presence of, and age at, antecedent events; gender; and distribution of spikes (bilateral ...extratemporal). In those who had surgery we also extracted information on histological ... See full document

... examine temporal pole (TP) signal and quantitative changes in temporal lobe epilepsy (TLE) patients with hippocampal sclerosis (HS) using coronal fluid-attenuated ... See full document

... esial temporal lobe epilepsy (MTLE) is the most prevalent refractory epilepsy in adolescents and adults, and its pathologic hallmark is classic hippocampal ... See full document