[PDF] Top 20 HIV/SIV infection primes monocytes and dendritic cells for apoptosis.
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HIV/SIV infection primes monocytes and dendritic cells for apoptosis.
... by HIV could lead to the observed changes in the sensitivity of these cells to undergo apoptosis without active replication ...We and others have previously reported the critical role of ... See full document
16
Drug-induced reactivation of apoptosis abrogates HIV-1 infection.
... productively and latently HIV-infected lymphocytes or macrophages by re-activation of apoptosis via the intrinsic pathway, irrespective of whether the compound is able (CPX, DEF, flavopiridol) or ... See full document
22
Major depletion of plasmacytoid dendritic cells in HIV-2 infection, an attenuated form of HIV disease.
... Plasmacytoid dendritic cells (pDC) provide an important link between innate and acquired immunity, mediating their action mainly through IFN-a ...suppress HIV-1 replication, but there is ... See full document
13
Effect of plasma viremia on apoptosis and immunophenotype of dendritic cells subsets in acute SIVmac239 infection of Chinese rhesus macaques.
... vitro, HIV Nef mediated CCR5 endocytosis and degradation ...expression and upregulated the CCR7 expression after being stimulated by HIV ...in HIV-infected patients, while that of pDCs ... See full document
11
Microbial Translocation and B Cell Dysfunction in Human Immunodeficiency Virus Disease
... in HIV-associated B cell perturbations. Loss of memory B cells and reduced production of antigen-specific antibody is seen in the majority of chronic HIV infection even though the ... See full document
8
Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients.
... of HIV-1 patients secrete higher amounts of IFNa by using a flow cytometry-based assay in the absence of exogenous stimuli that may yield artifactual results ...in HIV-1 patients both at the RNA and ... See full document
12
Effects of Epstein-Barr virus on the development of dendritic cells derived from cord blood monocytes: an essential role for apoptosis
... blood monocytes in the presence of GM-CSF and IL-4, was ...infect monocytes and inhibit their differentiation into ...vitro, and the cell death was associated with nucleosomal cleavage ... See full document
8
HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation.
... groups and showing the capacity of kynurenine pathway inhibitors, including 1MT (1-methyl-tryptophan), to interfere with its effects both in vitro [37,76,80] and in vivo ...PBMC, and then infected by ... See full document
12
Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.
... SVF cells and ...treatment, HIV DNA was detected in the SVF of all samples tested (11 from VAT and 4 from SCAT) (Fig ...of HIV DNA in SVF from VAT (2.15 [2.01–2.47] log DNA ... See full document
28
Full restoration of Brucella-infected dendritic cell functionality through Vγ9Vδ2 T helper type 1 crosstalk.
... T cells expressing Vc9Vd2 antigen receptors belong to the family of innate ...innate and adaptive immunity and play a crucial role in both antitumoral and anti-infectious ...T cells are ... See full document
11
HIV-1 infection on Follicular Helper T cells
... of HIV infection, preventing millions of AIDS-related deaths and improving HIV- infected individual’s life ...persistent HIV reservoirs which remain the major obstacle to a functional ... See full document
69
Quantification of the frequency and multiplicity of infection of respiratory- and lymph node-resident dendritic cells during influenza virus infection.
... (IAV) infection, respiratory dendritic cells (rDC) mature, upregulate costimulatory molecules, and migrate to the regional lymph nodes (LN) where they participate in the induction of ... See full document
6
Cecum lymph node dendritic cells harbor slow-growing bacteria phenotypically tolerant to antibiotic treatment.
... tolerant cells and allows cell retrieval with minimal risk of contamination ...sacrificed and we recovered the cecum content, the cLN, and the ...sample and pathogen loads were verified ... See full document
15
Resident CD8(+) and migratory CD103(+) dendritic cells control CD8 T cell immunity during acute influenza infection.
... T cells. If the T cells respond, it is indicative that the co-cultured DC subtype is presenting ...types and then staining for pan-DC marker CD11c as well as the markers CD8, CD103 and ... See full document
7
Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages.
... spectrophotometrically, and the quality was assessed with the Agilent 2100 bioanalyzer (Agilent Technol- ogies Inc, Palo Alto, ...yield and no RNA degradation (28S:18S .1.7 and RNA integrity num- ber ... See full document
14
Normal skin of HIV-infected individuals contains increased numbers of dermal CD8 T cells and normal numbers of Langerhans cells
... in HIV infec- tion have focused on the role of Langerhans cells (Lc), most probably because of their important function as antigen-presenting cells and because of their expression of CD4 ... See full document
9
Opiates Upregulate Adhesion Molecule Expression in Brain MicroVascular Endothelial Cells (BMVEC): Implications for Altered Blood Brain Barrier (BBB) Permeability
... endothelial cells and perivascular astrocytes that restrict the passage of immunocompetent cells into the central nervous system ...(ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on ... See full document
9
Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells.
... THP-1 cells and extended the analysis to include detection of apoptosis in bone marrow–derived macrophages (BMDMs) from BALB/c mice following infec- ...more apoptosis than the complemented ... See full document
9
Direct infection of dendritic cells during chronic viral infection suppresses antiviral T cell proliferation and induces IL-10 expression in CD4 T cells.
... MHC and co- stimulatory molecules (MHC I, II, CD80 and CD86), as well as increased inhibitory molecules PD-L1 and (to a lesser extent) PD- ...exposed and directly infected APCs, but rather ... See full document
10
Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells.
... infected cells were harvested and subjected FAIRE followed by next generation ...(+) monocytes were infected with FIX BAC virus and cells were harvested at 4 and 18 days post ... See full document
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