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[PDF] Top 20 Impaired bone formation in Pdia3 deficient mice.

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Impaired bone formation in Pdia3 deficient mice.

Impaired bone formation in Pdia3 deficient mice.

... (RunX2), bone sialoprotein (Bsp), osteopontin (Opn), and osteoprotegerin (Opg) and normalized to the level of housekeeping gene ribosomal protein s 18 ...listed in Table ...osteocalcin in the media ... See full document

11

Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.

Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.

... disturbed in the whole area of cortical ...promoted bone formation at 4 months of age, this seemed to be unlikely because overexpres- sion of BCL2 impaired osteoblast differentiation in ... See full document

20

Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice.

Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice.

... Adult bone mass was affected by Gli1 haploinsufficiency in mice, although body length and body weight were ...low bone mass phenotypes were accompanied by impaired bone ... See full document

11

Hippocampal network oscillations in APP/APLP2-deficient mice.

Hippocampal network oscillations in APP/APLP2-deficient mice.

... enriched in the brain but are also ubiquitously expressed in other tissues while APLP1 expression is restricted to neurons ...involved in cell adhesion, neuronal maturation and synaptogenesis ... See full document

7

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice.

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice.

... cells in bone healing remains ...mainly in later stages of fracture healing [10]. Bone healing was improved in lymphocyte-deficient, recombination activating gene-1 ... See full document

12

Egr3 dependent sympathetic target tissue innervation in the absence of neuron death.

Egr3 dependent sympathetic target tissue innervation in the absence of neuron death.

... knockout mice or sympathetic neurons isolated from Bax- deficient mice devoid of NGF treatment in vitro, terminal axon extension and innervation abnormalities were observed to differing ... See full document

10

Lactation defect with impaired secretory activation in AEBP1-null mice.

Lactation defect with impaired secretory activation in AEBP1-null mice.

... tissue in which morphological changes and differentiation occur cyclically during menstruation, pregnancy and ...lactation. In prepubescent mice, the gland consists of a small ductal tree that ... See full document

9

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner.

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner.

... result in atheroscle- rotic plaque rupture and subsequent superimposed thrombus formation ...important in atherogenesis [7]. In addition to the overt leukocyte infiltration into the lesions ... See full document

14

J. Appl. Oral Sci.  vol.13 número3

J. Appl. Oral Sci. vol.13 número3

... 13- Deutsch D, Palmon A, Fisher LW, Kolodny N, Termine JD, Young MF. Sequencing of bovine enamelin (“tuftelin”) a novel acidic enamel protein. J Biol Chem. 1991 Aug 25;266(24):16021-8. 14-DuPont BR, Hu CC, Reveles X, ... See full document

6

Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient mice.

Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient mice.

... unchanged in the optic nerve and brain, and in fact, it attenuated in the spinal cord in Olig1 2/2 mice (Figure ...myelin formation despite the altered level of MOG, MAG and MBP ... See full document

11

Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.

Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.

... disturbed in SUN1 deficient meiocytes (Figure 1A9 and ...located in the nuclear interior, in significant distance to the ...(arrowheads in A9 and A90), indicating that in the ... See full document

9

The effect of simvastatin on the regeneration of surgical cavities in the femurs of rabbits

The effect of simvastatin on the regeneration of surgical cavities in the femurs of rabbits

... ixed in 10% formalin and were decalciied in trichloroacetic acid (5%) for 20 ...each bone was sectioned level with the cavity and soaked in parafin ...the bone cavities in each ... See full document

6

Adaptive gene regulation in the Striatum of RGS9-deficient mice.

Adaptive gene regulation in the Striatum of RGS9-deficient mice.

... milk in Tris- buffered saline (50 mM Tris, pH ...washing in TBST, membranes were incubated with horseradish peroxi- dase-linked anti-mouse, -goat or -rabbit secondary antibody (Dianova, Hamburg, Germany) ... See full document

12

Identifying activated T cells in reconstituted RAG deficient mice using retrovirally transduced Pax5 deficient pro-B cells.

Identifying activated T cells in reconstituted RAG deficient mice using retrovirally transduced Pax5 deficient pro-B cells.

... markers in addition to cytokine-based assays. In contrast to these published methods, we here describe a strategy to identify T cells that respond to any antigen and track the fate of these activated T ... See full document

5

Bisphosphonates in the treatment of metabolic bone diseases

Bisphosphonates in the treatment of metabolic bone diseases

... placebo in postmenopausal women with osteo- porosis ...incidence in a group of men and women who received zoledronic acid infusion within 90 days after surgical repair of a low-trauma hip fracture, reported ... See full document

7

Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse.

Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse.

... insufficiency in AIP mice may aggravate the acute porphyria ...pathophysiology in AIP patients afflicted by recurrent acute attacks and renal ...condition in which the development of severe ... See full document

9

Functional deficiency of MHC class I enhances LTP and abolishes LTD in the nucleus accumbens of mice.

Functional deficiency of MHC class I enhances LTP and abolishes LTD in the nucleus accumbens of mice.

... [34]. In this experiment, mice were given intraperitoneal injections of either saline or cocaine (20 ...injections, mice were divided into groups that received seven daily injections of either saline ... See full document

8

TGF-β and new bone formation

TGF-β and new bone formation

... reduction in bone size at birth (Liu et ...potentiating bone regeneration (Trippel, 1998; Shukunami et ...roles in the anabolic regulation of bone and cartilage metabolism (Thomas et ... See full document

7

The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.

The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.

... performed in accordance with the protocols approved by the ani- mal care use committee of the University of California, San Diego following National Institutes of Health guidelines for the humane treatment of ... See full document

15

Mice with deficient BK channel function show impaired prepulse inhibition and spatial learning, but normal working and spatial reference memory.

Mice with deficient BK channel function show impaired prepulse inhibition and spatial learning, but normal working and spatial reference memory.

... 2/2 mice could perform all tasks required for the cognitive tests that we ...cells in the basal cochlea and that a deletion of the pore forming a-subunit of the BK channel leads to progressive hearing loss ... See full document

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