[PDF] Top 20 Inferring modules from human protein interactome classes
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Inferring modules from human protein interactome classes
... choice from the available ...our modules, and emphasize their permanent ver- sus transient ...a protein pathway context, we could com- pare the detected modules with pre-assigned confidence ... See full document
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Inferring gene-phenotype associations via global protein complex network propagation.
... module. Protein complexes, as molecular machines that integrate multiple gene products to perform biological functions, are direct manifestations of biological ...such, protein complexes can be a useful ... See full document
11
A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome.
... proteins from the immediate neighborhood of the seed ...e.g. from GWAS, microarray experiments and comorbidity analysis, has experimentally confirmed the specific disease-relevance of the DIAMOnD genes and ... See full document
21
A viral-human interactome based on structural motif-domain interactions captures the human infectome.
... and modules to produce different phenotypes as showed by McGary et al ...of human-pathogen relation- ships and for other essential ...in human tumors grafted into ...data from ... See full document
13
Inferring the Clonal Structure of Viral Populations from Time Series Sequencing.
... virus from its parent ...identify from sequencing ...structure from a time series of sequencing experiments, which can also detect reassortment events, thus providing a method to help improve the ... See full document
26
Topographic factor analysis: a Bayesian model for inferring brain networks from neural data.
... 1. Inferring the hidden structure underlying a set of brain ...slices from a single ...inferred from the same participant’s data, each source is represented as a dark gray sphere (whose radius ... See full document
14
Inferring Pairwise Interactions from Biological Data Using Maximum-Entropy Probability Models.
... Similar to the derivation of the mean-field result (20), Jones et al. [8] approximated Eq 12 by a multivariate Gaussian and accessed the elements of the inverse covariance matrix by a maxi- mum-likelihood inference under ... See full document
22
Inferring emotions from speech prosody: not so easy at age five.
... objects, human behavior is generally interpreted in terms of ...gathered from the external world, through the senses, and some of them are stored, ... See full document
8
Identification of a novel nuclear localization signal sequence in Chlamydia trachomatis-secreted hypothetical protein CT311.
... ref: [14], rabbit anti-Nup153 (cat#HPA-027896, Sigma), rabbit anti-V5 tag (cat# GTX117997, Genetex, Irvine, CA) and rabbit anti-chlamydial organisms (R1L2, unpublished data). The primary antibody binding was visualized ... See full document
7
A human-specific de novo protein-coding gene associated with human brain functions.
... any human-specific new genes may be associated with human brain functions, we computationally screened the genetic vulnerable factors identified through Genome-Wide Association Studies and linkage analyses ... See full document
11
Pharmacological inhibition of dynamin II reduces constitutive protein secretion from primary human macrophages.
... exit from processing in the Golgi ...immunoprecipitated from media and cell lysates, separated by SDS-PAGE and quantified by ...media from [ 35 ... See full document
13
Contribution to drug discovery and development for tauopathies using yeast as a model
... characterized human homologue ...and human, further supporting the use of yeast in modelling human ...1 protein, as a suppressor of tau toxicity (Ambegaokar & Jackson, ...and ... See full document
259
Inferring climate variability from nonlinear proxies: application to paleo-ENSO studies
... Table 1. Inference diagnostics derived from 10 000 realizations of the climate process c(t), for each of the three inference approaches, with δ = 0.5. CI width is the width of the 95 % uncertainty intervals ... See full document
47
Automated System for interpreting Non-verbal Communication in Video Conferencing
... Hidden Markov Models (HMMs) have been widely used to model the temporal behaviors of facial expressions from image sequence. Cohen et al. proposed a multi-level HMM classifier, which allows not only performing ... See full document
6
An alternative chemical redox method for the production of bispecific antibodies: implication in rapid detection of food borne pathogens.
... Bi-functional antibodies with the ability to bind two unrelated epitopes have remarkable potential in diagnostic and bio- sensing applications. In the present study, bispecific antibodies that recognize human red ... See full document
13
A note on prime modules
... prime modules leads us to define prime object in categories of Grothendieck (or more generally, in any category where there exist bounded localizant subcategories) and the notion of a Φ-prime module in Ore ... See full document
12
Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria.
... resulting from HNE treatment, suggesting a loss of 3-kD peptide from the 25 kD native SPLUNC1 ...SPLUNC1 protein can be cut by HNE remains to be ...normal human airway epithelial ...SPLUNC1 ... See full document
7
The reconstruction of condition-specific transcriptional modules provides new insights in the evolution of yeast AP-1 proteins.
... the protein Yap1p can control the transcription of different sets of genes, depending on the origin of the oxidative stress and on the subsequent post-translational modifications of Yap1p ...multigenic ... See full document
12
Inferring Strain Mixture within Clinical Plasmodium falciparum Isolates from Genomic Sequence Data.
... isolates from eight countries on three conti- nents showed the parasite to exhibit significant population structure at continental scales, with the amount of subpopulation structure varying significantly among ... See full document
20
Rev. Bras. Hematol. Hemoter. vol.26 número1
... of human protein privation have largely been based on information obtained from severely malnourished individuals, suffering multiple nutritional deficiencies, or from patients with chronic ... See full document
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