[PDF] Top 20 An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing.
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An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing.
... variety of mechanisms. A somatic substitution in LUDLU-1 is likely to lead to p53 ...Trp53, the ortholog in mice, does not directly cause cancer but increases the likelihood ... See full document
8
Predictive efficacy of low burden EGFR mutation detected by next-generation sequencing on response to EGFR tyrosine kinase inhibitors in non-small-cell lung carcinoma.
... Direct sequencing remains the most widely used method for the detection of epidermal growth factor receptor (EGFR) mutations in lung cancer; however, its relatively low ... See full document
8
Molecular typing of lung adenocarcinoma on cytological samples using a multigene next generation sequencing panel.
... deep sequencing with the Ion AmpliSeq Colon and Lung Cancer ...showed an EGFR exon 21 L858R mutation in Figure ...aspiration of lung nodules and mutations ... See full document
6
SubClonal Hierarchy Inference from Somatic Mutations: Automatic Reconstruction of Cancer Evolutionary Trees from Multi-region Next Generation Sequencing.
... improvements in next-generation sequencing of tumor samples and the ability to identify somatic mutations at low allelic fractions have opened the way for ... See full document
26
Copy number variation of individual cattle genomes using next-generation sequencing
... advent of next-generation sequencing (NGS) and com- plementary analysis programs has provided better approaches to systematically identify CNVs at a genome-wide ...to the ongoing ... See full document
14
Application of Next-generation Sequencing in Clinical Molecular Diagnostics
... to the data from human genome project, in 10–20 ...employed in which NGS is being applied for identifying causal gene variant in the rare ...Whole-exome sequencing (WES), ... See full document
15
SQUAMOUS CELL CARCINOMA IN OVINES IN THE STATE OF ACRE1
... - The squamous cells carcinoma (SCC), also known as epidermoid carcinoma, is a malign neoplasia of the squamous layer of the skin’s epidermis, very common ... See full document
5
Diagnostic value of α-enolase expression and serum α-enolase autoantibody levels in lung cancer
... subtypes in the groups of patients with adenocarcinoma, squamous cell carcinoma, and other types of lung cancer showed that ENO1 antibody levels were not ... See full document
6
Subungual Squamous Cell Carcinoma Masquerading as an Onychomycosis
... service in 2010 with an inlamed, necrotic, and discharging lesion underneath the nail of his right thumb (Figure ...history of immunosuppression or ...scanning using technetium ... See full document
3
Helicobacter pylori seropositivity and risk of lung cancer.
... number of cigarettes per day (continuous), tooth loss (continuous), dentures (yes/no), obesity (ordinal body mass index ,25, 25–30, 30+), asthma (yes/no), emphysema (yes/no), bronchitis (yes/no), and education ... See full document
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CAFET algorithm reveals Wnt/PCP signature in lung squamous cell carcinoma.
... (CAFET). In the first step, data for pathway members are extracted from the gene expression ...matrix. In the second key step, CAFET identifies samples with a relevant gene expression ... See full document
11
MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma.
... family of small, non-coding RNA species functioning as negative regulators of multiple target genes including tumour suppressor genes and ...miRNAs in lung cancer, we inferred miRNA gene ... See full document
10
Development and characterization of novel microsatellite markers by Next Generation Sequencing for the blue and red shrimp Aristeus antennatus
... ten of the putative microsatellite markers presented a minimum of 30 flanking bp, likely useful for primer design and Primer 3 software suggested specific primer pairs for 97 of these ...were ... See full document
14
Exhaled breath analysis for lung cancer detection using ion mobility spectrometry.
... parameters of breath analysis have been previously summarized [11– 21] and will be discussed here in ...to the detection of ions formed from analysis at ambient pressure within a drift ... See full document
13
Transcriptional profiling of endocrine cerebro-osteodysplasia using microarray and next-generation sequencing.
... mutation in ICK encoding intestinal cell ...profiling using both cDNA microarrays and next- generation mRNA sequencing (mRNA-seq) of skin fibroblasts from ECO-affected ... See full document
8
Sao Paulo Med. J. vol.116 número6
... washing in PBS buffer (pH 7.6) and incubation for 20 minutes in 1:10 normal horse serum in a humid chamber at room temperature, sections were incubated overnight, at 4°C in a humid chamber, ... See full document
6
Rev. Bras. Ginecol. Obstet. vol.36 número5
... and mutations in phosphatase and tensin homolog (PTEN) in patients with stage IB cervical squamous cell carcinoma (CSCC) and the association with clinical-pathologic ... See full document
6
The de novo assembly of mitochondrial genomes of the extinct passenger pigeon (Ectopistes migratorius) with next generation sequencing.
... between the rock pigeon (Columba livia, GenBank accession number GU908131) and each of the three passenger pigeons (one unpublished sequence with a GenBank accession number JQ692598 and two sequenced ... See full document
9
Promising Immuno-Oncology Treatments Beyond the 2018 Nobel Prize
... leukemia, lung, renal, breast cancers, among ...having the benefit of faster TKIs response and potentially long term responses with ...ICIs. In advanced renal cell carcinoma, ... See full document
7
Sao Paulo Med. J. vol.125 número5
... history of recurrent perianal and anal ...fulguration in another institution on two occasions. He had been using HAART over the past two ...part of the anal canal and the ... See full document
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