[PDF] Top 20 Interface-resolved network of protein-protein interactions.
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Interface-resolved network of protein-protein interactions.
... an interface-interaction network (IIN) to capture the specificity and competition between protein-protein interactions ...type of network represents interactions ... See full document
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A viral-human interactome based on structural motif-domain interactions captures the human infectome.
... achieve interface mimicry without any sequence or structural similarity to a human binding partner and the interaction among viral and human proteins are transient and regulatory in ...peptide-domain ... See full document
13
Protein-protein interactions in clathrin vesicular assembly: radial distribution of evolutionary constraints in interfaces.
... area of every ...the protein-protein interaction interfaces solely from Ca positions in low resolution structures of big assemblies such as CCV ...terms of the interacting residues. The ... See full document
11
Predicting protein phenotypes based on protein-protein interaction network.
... contribution of many ...the interactions of seed protein YBR039W with the other seed proteins are listed in Table ...that protein YBR039W and its neighbors YBL099W, YDL004W, YDR298C, ... See full document
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Distilling a Visual Network of Retinitis Pigmentosa Gene-Protein Interactions to Uncover New Disease Candidates.
... view of the molecular and cellu- lar basis of the disease, which is indispensable to approach efficient therapy, we need new tools and ...type of approach has already been explored by geneticists and ... See full document
18
Protein-protein interactions within late pre-40S ribosomes.
... the protein-protein interactions between the seven non-ribosomal proteins bound to pre-43S ribosomes using recombinant proteins in in vitro binding ...the interactions between these factors ... See full document
10
Changes in protein interaction networks between normal and cancer conditions: Total chaos or ordered disorder?
... the interactions were considered among the 722 signaling proteins, other predicted interacting proteins were ...possible interactions among them. Differential expressions of the signaling ... See full document
14
Predicting Protein-Protein Interactions Using BiGGER: Case Studies
... most protein docking software, in that BiGGER was conceived as a tool to help researchers elucidate protein interactions rather than as an automated ...2 of the Critical Assessment of ... See full document
19
Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.
... molecular interactions, which in turn determine biological functions of ...how protein sequences define interaction specificity is largely missing, in particular for paralogous protein ... See full document
13
Protein-protein interactions as a strategy towards protein-specific drug design: the example of ataxin-1.
... domain of the transcriptional co-regulator ATX1 has been a continuous source of surprise from the structural point of ...example of a chameleon protein that is able to adopt distinct ... See full document
9
Protein-protein interface detection using the energy centrality relationship (ECR) characteristic of proteins.
... each of the resultant interfaces, we performed a limited literature search focused on identifying: (1) whether the proteins were known to oligomerize in vivo; (2) whether the proteins were known to oligomerize in ... See full document
13
Wiki-pi: a web-server of annotated human protein-protein interactions to aid in discovery of protein function.
... Protein-protein interactions (PPIs) are the basis of biological ...Knowledge of the interactions of a protein can help understand its molecular function and its ... See full document
10
UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks
... regulatory interactions from three complementary databases TRANSFAC (19), miRTarBase (20) and HTRIdb ...these interactions, we also integrated drug target information from DrugBank (22) that can be mapped ... See full document
7
Computational analysis of HIV-1 resistance based on gene expression profiles and the virus-host interaction network.
... member of the retrovirus family ...infection of helper T cells (CD4+ T cells), macrophages, and dendritic cells ...proportions of individuals are resistant to HIV-1 infection and remain negative ... See full document
6
On the growth of scientific knowledge: yeast biology as a case study.
... is of great interest to understand the patterns and mechanisms of scientific knowledge growth, but such studies have been hampered by the lack of ideal cases in which the structure of the ... See full document
12
Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.
... number of times two predicted interacting prey proteins have a domain on each side of the ...type of analysis we did for PPIs, we also attempted to further combine different prediction methods to ... See full document
10
The many faces of protein-protein interactions: A compendium of interface geometry.
... classification of protein–protein interfaces is a valuable resource for understanding the principles of molecular recognition and for modelling protein ...classification of ... See full document
14
Predicting and validating protein interactions using network structure.
... Protein interactions play a vital part in the function of a ...validation of protein interactions are time consuming, there is a need for computational methods for this ...task. ... See full document
11
Composition of Overlapping Protein-Protein and Protein-Ligand Interfaces.
... Protein-protein interactions (PPIs) play major roles in many biological processes such as bio- energetics, immune response, signal transduction, structural organization, and apoptosis ...lack ... See full document
18
Identification of an FHL1 protein complex containing gamma-actin and non-muscle myosin IIB by analysis of protein-protein interactions.
... modular protein binding interface to mediate protein-protein ...the interactions of FHL1 could provide important new insights into its functional role in both skeletal muscle ... See full document
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