[PDF] Top 20 Interleukin 8 as a vaso-occlusive marker in Brazilian patients with sickle cell disease

... Sickle cell disease has a worldwide distribution and is a public health problem in ...Although vaso-occlusive crisis (VOC) is one of the most important clinical features of the ... See full document

... Sickle cell disease is an inflammatory condition with a pathophysiology that involves vaso-occlusive ...vascular disease. Due to the importance of identifying risk factors ... See full document

... [25]. Sickle cell anemia is a hemolytic red cell disorder and all patients with SCD have variable degrees of hemolysis and it is most severe in ...hemolysis in SS varies ... See full document

... Pregnancy in patients with sickle cell disease (SCD) has always been a challenge for both hematologists and ...the sickle vaso-occlusive process has enabled ... See full document

... cytokine with potent anti-inlammatory activity which reduces the production of various cytokines including IL-1, IL-6, IL-8, IL-12, TNF-α and GM-CSF to promote uptake and retention of iron in the ... See full document

... therapy with packed red blood cells (PRBCs) is a common practice in the treatment and prevention of complications in sickle cell anemia ...of patients with SS receive ... See full document

... Sickle cell disease (SCD) is one of the most common hemo- globinopathies in the ...Turkey; in some areas such as the Çu- kurova region, this frequency reaches up to ...inlammatory ... See full document

... reported in most interna- tional studies (8,11). A Brazilian study (15) reported 20% anti-D antibody among a total of 15 alloantibodies ...found in the present study may be attributed to several ... See full document

... involvement in sickle cell disease has been poorly studied and it is mainly characterized by osteonecrosis, osteomyelitis and ...care in sickle cell disease ... See full document

... Sickle Cell Disease (SCD) is a clinically significant haemoglo- binopathy with increasing incidence in developed ...1 in every 2000 births in England and it is estimated ... See full document

... Sickle cell disease is associated with glomerular and tabular structural abnormalities, hemodynamic changes and renal hormone synthesis alterations (erythropoietin, renin, ...appear in ... See full document

... – Sickle cell disease causes chronic and recurrent hemolysis which is a recognized risk factor for ...occurs in 50% of adults with sickle cell ...symptomatic ... See full document

... study with 160 children with different renal diseases found a significant association between the inability to concentrate urine and glomerular filtration rate [36], but we did not found this in our ... See full document

... region, with a significant increase in genotype A/A (mutant) compared to G/G genotype ...associated with the region rs7557939 on the BCL11A gene in SCD adult patients at ...polymorphism ... See full document

... The disease is not uniformly seen everywhere but it has some topographical ...distribution. In India, it is frequently seen in Central India, in and around the vicinity of Chhattisgarh ... See full document

... diferences in terms of age and weight between both groups, we did not find that those differences affected the patient ...management. In our cohort, A-RBCX decreased HbS levels more efficiently than manual ... See full document

... com vaso-oclusão, também têm sido ligadas à HP, como a ß-talassemia intermedia, a doença da hemoglobina H, a esferocitose hereditária, a estomatocitose hereditária e a hemoglobinúria paroxística noturna (HPN) ... See full document

... published in 1997 of 149 patients (14 patients under 15 years old), the indications for splenectomy were hematological diseases (27%), trauma (33%), incidental (12%), accidental (20%) and others ... See full document

... analyses. In immunoserology, elevated titres of antinuclear antibodies and circulating immune complexes were present, while other analyses (anticardiolipin antibodies and lupus anticoagulant) were ...syndrome ... See full document

... Patients were assessed for potential inclusion at the time of admission in the ICU or immediately after the diagnosis of sepsis, in case they were already at the ICU. The clinical data were collected ... See full document