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[PDF] Top 20 Kruppel-like factor 2 is required for normal mouse cardiac development.

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Kruppel-like factor 2 is required for normal mouse cardiac development.

Kruppel-like factor 2 is required for normal mouse cardiac development.

... [42], like FVB/N KLF2 ...expression is reduced 3-fold in the absence of KLF2 in FVB/N AV ...in cardiac defects like atrial septal defects (ASD), AV septal defects (AVSD) and myocardial ... See full document

13

A Myb transcription factor of Phytophthora sojae, regulated by MAP kinase PsSAK1, is required for zoospore development.

A Myb transcription factor of Phytophthora sojae, regulated by MAP kinase PsSAK1, is required for zoospore development.

... pathway is the identification of downstream genes that are regulated by ...PsMYB1 is transcriptionally suppressed after loss of PsSAK1, and silencing of PsMYB1 does not affect the transcriptional level of ... See full document

12

Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina.

Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina.

... it is not critical for their ongoing ...postnatal development there are changes in amacrine cell numbers in APP-KO compared to WT retina, by adulthood, with the exception of the AII amacrine cells, this ... See full document

10

Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish.

Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish.

... of cardiac markers in Smyd3 morphants To further disclose the mechanism(s) of heart defect in Smyd3 morphants, we studied the expression of seven markers; four anterior lateral plate mesoderm (ALPM) markers ... See full document

7

Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract.

Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract.

... formation is controlled by several transcription factors [12,13,14], including the zinc finger transcription factor Gli3 which is expressed in progenitor cells of the dorsal and ventral telencephalon ... See full document

17

Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis.

Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis.

... Fgf10 2/2 and Fgfr2b 2/2 embryos indicating a role of FGF10-FGFR2b mediated signaling in promoting antralization ...stomach development resulted in a SPEM-like phenotype with a ... See full document

12

Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice.

Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice.

... containing normal Rabbit serum (Dako, Glostrup, Denmark), incubated with Anti-Mouse CD45 (BD Pharmingen, Franklin Lakes, NJ, USA) and then with biotin- conjugated secondary Rabbit anti-Rat antibody ... See full document

10

The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis

The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis

... showed normal expression, 50% displayed bilat- eral expression, and 10% had an inverted pattern of ex- pression in the R-LPM ...node is reported not to be necessary or linked to its later expression domain ... See full document

7

Jun is required in Isl1-expressing progenitor cells for cardiovascular development.

Jun is required in Isl1-expressing progenitor cells for cardiovascular development.

... for normal OFT development and ...Jun is clearly required in one or more of these cell ...embryonic development in the mouse is lacking in the literature, particularly ... See full document

13

Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages.

Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages.

... adhesion development in mice [14], CCL1 is produced by mesothelial cells and macrophages in the peritoneal cavity and is a potent enhancer of CCR8 expression in peritoneal macrophages (PMQ) [14], and ... See full document

12

DNA methyltransferase 3b is dispensable for mouse neural crest development.

DNA methyltransferase 3b is dispensable for mouse neural crest development.

... cells is surprising given that animals fully mutant for DNMT3b have defects in neural crest derivatives ...be required in cell types with which neural crest cells interact during their differentiation, such ... See full document

9

Semaphorin-1a is required for Aedes aegypti embryonic nerve cord development.

Semaphorin-1a is required for Aedes aegypti embryonic nerve cord development.

... during development of both the ...of development post-injection of siRNA-control injected (A) and sema siRNA-injected (B–F) ...connective is marked by a white arrow; the anterior commissure is ... See full document

7

Ferritin Is Required in Multiple Tissues during Drosophila melanogaster Development.

Ferritin Is Required in Multiple Tissues during Drosophila melanogaster Development.

... 1:100, mouse α-BP102 1:100, mouse α-Eve 1:100 (Developmental Studies Hybridoma Bank, Indiana, USA); α-activated Cas- pase 3 1:100 (Cell Signaling, USA); and rat α-Deadpan 1:2, a gift from Cheng-Yu ... See full document

20

A transcript cleavage factor of Mycobacterium tuberculosis important for its survival.

A transcript cleavage factor of Mycobacterium tuberculosis important for its survival.

... the C-terminal globular domain of Gre factors (GreA, GreB of E. coli and MtbGre), which interacts with the RNAP, shows considerable variation, although certain specific residues in the hydrophobic patch are conserved in ... See full document

13

Targeted Inactivation of Cerberus Like-2 Leads to Left Ventricular Cardiac Hyperplasia and Systolic Dysfunction in the Mouse

Targeted Inactivation of Cerberus Like-2 Leads to Left Ventricular Cardiac Hyperplasia and Systolic Dysfunction in the Mouse

... for normal heart development such as Gata-4 and ...contractility like a-Mhc and cTnT, which are activated by the transcription factors Gata-4 and Mef2 ...and cardiac stress [49,50] were ... See full document

12

Doxycycline inducible Kruppel-like factor 4 lentiviral vector mediates mesenchymal to epithelial transition in ovarian cancer cells.

Doxycycline inducible Kruppel-like factor 4 lentiviral vector mediates mesenchymal to epithelial transition in ovarian cancer cells.

... transcription factor Kru¨ppel-like factor 4 (KLF4) has been implicated in human cancers as a tumor suppressor or oncogene, although its role depends greatly on the cellular ...growth factor b ... See full document

9

E-cadherin promotes incorporation of mouse epiblast stem cells into normal development.

E-cadherin promotes incorporation of mouse epiblast stem cells into normal development.

... First, we applied qPCR analysis to quantify the expression levels of the E-cadherin transgene and the endogenous genes associated with pluripotency [9,10,11,12]. The results confirmed the in- ducible expression of ... See full document

8

Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.

Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.

... inv 2/2 MEFs showed a markedly reduced Rac1 and RhoA localization at cell surfaces facing the wound (Figure 5A,B, right ...inv 2/2 MEFs (Figure ...inv 2/2 MEFs, the defective ... See full document

15

The 3-hydroxy-2-butanone pathway is required for Pectobacterium carotovorum pathogenesis.

The 3-hydroxy-2-butanone pathway is required for Pectobacterium carotovorum pathogenesis.

... (acyl-HSL), is also affected by pH and it is hydrolyzed into an inactive form above pH ...it is thought to be responsible for the growth promoting effects of some PGPB ...budB is not impaired ... See full document

11

The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos.

The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos.

... repression is mediated by a 90-nucleotide translational control element (TCE) in the 3 9UTR of nanos mRNA [14,15,16,17,18] to which Smaug (Smg) or Glorund (Glo) bind ...mRNA is regulated by the Oskar (Osk) ... See full document

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