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[PDF] Top 20 Leukotrienes Produced in Allergic Lung Inflammation Activate Alveolar Macrophages

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Leukotrienes Produced in Allergic Lung Inflammation Activate Alveolar Macrophages

Leukotrienes Produced in Allergic Lung Inflammation Activate Alveolar Macrophages

... enzymes. Leukotrienes are produced in a multi-step enzyme pathway called the 5-lipoxygenase (5-LO) pathway, which is active in leukocytes such as neutrophils, eosinophils, mast cells and ... See full document

8

Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice

Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice

... that in mice there is an association between CS-induced emphysema and increased pulmonary HMGB- 1 expression ...the inflammation, is a consequence of it or, indeed, is directly involved at all, the protein ... See full document

7

Epicutaneous exposure to staphylococcal superantigen enterotoxin B enhances allergic lung inflammation via an IL-17A dependent mechanism.

Epicutaneous exposure to staphylococcal superantigen enterotoxin B enhances allergic lung inflammation via an IL-17A dependent mechanism.

... only in the skin but also in the airways, which was independent of IL-4 and IL-13 [34], implicating IL-17 in the atopic ...is produced by various types of cells such as T cells, B cells, ... See full document

13

Defective lung macrophage function in lung cancer ± chronic obstructive pulmonary disease (COPD/emphysema)-mediated by cancer cell production of PGE2?

Defective lung macrophage function in lung cancer ± chronic obstructive pulmonary disease (COPD/emphysema)-mediated by cancer cell production of PGE2?

... and lung tissue compartments for individual patients; we are however assessing this in our murine emphysema model in ongoing ...‘normal’ lung. Although we collected our ‘control’ lung ... See full document

6

Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production

Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production

... and in spleen ...cells in a TGF-β-dependent manner ...maintenance in situ. In the present study, we used a well-established model of mucosal tolerance to allergic lung ... See full document

14

J. Pediatr. (Rio J.)  vol.82 número3 en v82n3a01

J. Pediatr. (Rio J.) vol.82 número3 en v82n3a01

... There is no integrated body of clinical or experimental information that can tell us the relative importance of adequate nutrition vs. mechanical ventilation, oxygen, infection and other factors in the development ... See full document

2

Histopathological and ultrastructural aspects of mice lungs experimentally infected with dengue virus serotype 2

Histopathological and ultrastructural aspects of mice lungs experimentally infected with dengue virus serotype 2

... (DHF/DSS) in hu- mans, with an estimated 100 million new cases of DF and over 250,000 cases of DHF/DSS per year world- ...difficulty in studying DENV infection in humans and for developing a vaccine, ... See full document

8

Cigarette smoking decreases global microRNA expression in human alveolar macrophages.

Cigarette smoking decreases global microRNA expression in human alveolar macrophages.

... expression in alveolar macrophages of smokers compared to nonsmokers was also observed when comparing the number of miRNAs with statisti- cally significant ...shown in Table 3 and Table 4, ... See full document

13

Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary disease.

Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary disease.

... receiving lung transplant, 9 GOLD 2–3 COPD subjects under- going resection of lung cancer (avoiding areas affected by tumor), and 8 non-COPD lung donors obtained following size adjustment for ... See full document

9

The Role of the Eosinophil-selective Chemokine, Eotaxin, in Allergic and Non-allergic Airways Inflammation

The Role of the Eosinophil-selective Chemokine, Eotaxin, in Allergic and Non-allergic Airways Inflammation

... of inflammation are areas of active ...step in extravasation is rolling of leu- kocytes along the venule wall, resulting from a loose, transient adhesion mediated largely by the selectin family of adhesion ... See full document

9

Effects of ischemia on lung macrophages.

Effects of ischemia on lung macrophages.

... mouse lung tissue was minced, digested (25 min in collagenase at 37 uC), and then pushed and washed through a 70 m M cell ...characterization in both bronchoalveolar lavage and lung, pooled ... See full document

8

Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice.

Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice.

... effects in vascular smooth muscle cells (VSMC), vascular endothelial cells (VEC) and human lens epithelial cells (HLEC) ...increase in inflammatory cytokines and chemokines in both cellular and ... See full document

13

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia.

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia.

... activation in the peri- toneum ...CLP in mice receiving antibiotic treatment [21]. In the latter study, RAGE deficiency or anti-RAGE therapy was reported not to influence bacterial loads in ... See full document

15

en 1679 4508 eins 1679

en 1679 4508 eins 1679

... results in destruction of the alveolar wall due to proteolytic enzymes action, which affects the extracellular matrix (ECM) (5) and its component integrity especially the elastic ... See full document

2

Effects of propofol pretreatment on lung morphology and heme oxygenase-1 expression in oleic acid-induced acute lung injury in rats

Effects of propofol pretreatment on lung morphology and heme oxygenase-1 expression in oleic acid-induced acute lung injury in rats

... gases in the blood were analyzed by a GEMpremierTM3000 blood gas analyzer (US Instrumentation Laboratory ...left lung of each rat was ...right lung of each rat was cut into a 0.3×0.3×0.5cm portion ... See full document

9

J. bras. pneumol.  vol.39 número6

J. bras. pneumol. vol.39 número6

... areas in each field were calculated on the basis of the number of points overlying connective tissue, as a proportion of the total grid ...cells in relationship to the total area covered by the grid ... See full document

9

Response activity of alveolar macrophages in pulmonary dysfunction caused by Leptospira infection

Response activity of alveolar macrophages in pulmonary dysfunction caused by Leptospira infection

... common in the tropics and in developing countries ...spirochetes in the ...The lung is a target of leptospiral infection, which develops hemorrhagic pneumonitis of different severity ...of ... See full document

13

Rev. bras. ter. intensiva  vol.22 número4

Rev. bras. ter. intensiva vol.22 número4

... both in English and Portuguese, were searched using the terms: cardiac surgery, cardiopulmonary bypass, mechanical ventilation, lung injury and respiratory distress ...included in the analy- ... See full document

9

Locust bean gum-based microparticles for pulmonary delivery of antibiotics

Locust bean gum-based microparticles for pulmonary delivery of antibiotics

... A determined amount of microparticles (of each formulation) were incubated with the respective media, under mild shaking (100 rpm, orbital shaker OS 20, Biosan, Latvia) at 37 °C. The released drug was quantified at ... See full document

106

The role of alveolar epithelium in radiation-induced lung injury.

The role of alveolar epithelium in radiation-induced lung injury.

... cytokines in fibrotic ...cells in radiation-induced fibrotic areas using GFP–positive bone marrow cells ...producing lung fibroblasts derived from bone marrow progenitor cells have been detected ... See full document

9

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