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[PDF] Top 20 Lineage relationship of prostate cancer cell types based on gene expression

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Lineage relationship of prostate cancer cell types based on gene expression

Lineage relationship of prostate cancer cell types based on gene expression

... the expression profile towards E given the rarity of progenitor ...CD31 gene in 04-126 was 1235 compared to 5336 (average of five) for the other 5D3 populations, 2719 (average of five) ... See full document

13

Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells.

Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells.

... subset of prostate stromal cells and functional stromal cell AR is required for normal prostate developmental and influences the growth of prostate ...aware of the ... See full document

11

Regulation of STEAP1 gene and its clinical significance in human prostate cancer

Regulation of STEAP1 gene and its clinical significance in human prostate cancer

... or cell, SERMs act either as agonists or antagonists, depending on the expression pattern of ERs and interaction with co-regulators that ultimately alter gene transcription [143, ... See full document

224

Genetic and epigenetic mechanisms involved in regulation of STEAP1 gene expression in LNCaP prostate cancer cells

Genetic and epigenetic mechanisms involved in regulation of STEAP1 gene expression in LNCaP prostate cancer cells

... disruption of this mechanism may lead to tumor development and progression ...One of the genes found unmethylated in PCa was the retrotransposable element 1 ...10% of the human genome, which are ... See full document

78

Expression changes in the stroma of prostate cancer predict subsequent relapse.

Expression changes in the stroma of prostate cancer predict subsequent relapse.

... majority of prostate cancer patients that would not die of the disease but receive radical ...nature of prostate tumors as well as cell-type heterogeneity between patient ... See full document

7

StemMapper: a curated gene expression database for stem cell lineage analysis

StemMapper: a curated gene expression database for stem cell lineage analysis

... stem cell (SC) biologists as well as for a wider research audience studying SC-related pro- cesses such as aging, embryonic development and prevalent diseases including cancer, diabetes and ... See full document

6

Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice.

Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice.

... later cell types do not actively express the GFP::Cre ...progenitor of the aforementioned cell types, perhaps the bone marrow ...group of progenitors each producing a single ... See full document

6

Expression analysis and regulation of steapi in prostate cell lines and in tissue microrrays of prostate tumors

Expression analysis and regulation of steapi in prostate cell lines and in tissue microrrays of prostate tumors

... TMAs of human prostate cancer, BPH, PIN and non-neoplastic tissue ...solution of ethanol. In order to block the activity of endogenous peroxidases, 2ml of H2O2 (3%) were added to ... See full document

92

GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells

GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells

... Several other metabolites identified were also able to discriminate between different cancer cell lines and normal cell lines, namely L-alanine (PC3 versus PNT2, DU145 versus PNT2, and L[r] ... See full document

15

MiRNA Profiles in Lymphoblastoid Cell Lines of Finnish Prostate Cancer Families.

MiRNA Profiles in Lymphoblastoid Cell Lines of Finnish Prostate Cancer Families.

... miRNA expression levels are predictive for the outcome of solid tumours and leukaemias, but the contribution of altered miRNA expression levels to ge- netic cancer susceptibility is not ... See full document

17

Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression.

Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression.

... tumor cell immunization ...amounts of c- irradiated cells followed by challenge with ...dose of immunization (5610 6 cells per mouse), both ...dose of immunization (5610 5 cells per mouse), ... See full document

11

Studying prostate cancer cell lines metabolome with FTIR spectroscopy

Studying prostate cancer cell lines metabolome with FTIR spectroscopy

... use of cell lines as cancer models was put in doubt in a study carried out by Baker and colleagues on the prostate-derived RWPE family of cell lines (RWPE-1, RWPE-2, ... See full document

71

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.

... these gene expression signatures at individual gene level (Figure ...performed Gene Ontology (GO) enrichment analysis for each signature using ...level of False Discovery Rate (FDR) ... See full document

13

Circulating MicroRNAs as Markers of Prostate Cancer Progression: a Time-based Approach

Circulating MicroRNAs as Markers of Prostate Cancer Progression: a Time-based Approach

... One of the most common benign diseases worldwide is benign prostatic hyperplasia (BPH), affecting approximately 50% of men between 51 and 60 years old and 90% of men with more than 80 years old [11, ... See full document

68

Expression of the Bcl-2 protein BAD promotes prostate cancer growth.

Expression of the Bcl-2 protein BAD promotes prostate cancer growth.

... protein of the Bcl-2 family, has recently been identified as an integrator of several anti-apoptotic signaling pathways in prostate cancer ...activation of EGFR, GPCRs or PI3K pathway ... See full document

6

Effect of Regucalcin on the expression of oncogenes and tumor suppressor genes in prostate cell lines

Effect of Regucalcin on the expression of oncogenes and tumor suppressor genes in prostate cell lines

... outgrowth of the epithelial buds is an androgen-driven process that requires AR expression in the surrounding urogenital mesenchyme to facilitate the reciprocal interactions between the epithelia and ... See full document

78

Demethylation of the epigenetically silenced androgen receptor gene by a repurposed drug in castration-resistant prostate cancer cell lines

Demethylation of the epigenetically silenced androgen receptor gene by a repurposed drug in castration-resistant prostate cancer cell lines

... one of the most powerful prognostic predictors and treatment selection tools in prostate cancer ...is based on five prostate cancers’ different histologic patterns ...Society ... See full document

108

MicroRNA expression and clinical outcome of small cell lung cancer.

MicroRNA expression and clinical outcome of small cell lung cancer.

... Although expression of the 7 microRNAs in our study was evaluated in many cancer types in vitro, in vivo, and in tumor specimens, they have not been evaluated before in relation to patient ... See full document

8

Gene expression profiling associated with angiotensin II type 2 receptor-induced apoptosis in human prostate cancer cells.

Gene expression profiling associated with angiotensin II type 2 receptor-induced apoptosis in human prostate cancer cells.

... downregulation of TRAIL-R2 significantly enhanced the apoptotic effect induced by AT2R ...The expression of cytokines in transduced DU145 ...groups of cells were mock ...analysis of ... See full document

12

Optimal use of prostate specific antigen for prostate cancer screening

Optimal use of prostate specific antigen for prostate cancer screening

... evaluation of almost 1,300 specimens, they docu- mented a strong association between the increasing PSA lev- els and prostate weight, or benign prostate hyperplasia (BPH), but not PCa 17 ...amount ... See full document

3

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