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The maspin expression in canine mammary tumors: An immunohistochemical and molecular study

The maspin expression in canine mammary tumors: An immunohistochemical and molecular study

... remodeling. In the past decade, with the expansion of studies on maspin, novel protein-binding partners have been identified and provided insight into the molecular ... See full document

7

Análise prognóstica da imunoexpressão de osteopontina no microambiente dos carcinomas mamários esporádicos de cadelas

Análise prognóstica da imunoexpressão de osteopontina no microambiente dos carcinomas mamários esporádicos de cadelas

... both in humans and animals and affect the malignant properties of neoplastic cells, specifically by affecting their ability to grow, invade, and ...expressed in both normal ... See full document

83

Retrospective canine skin peripheral nerve sheath tumors data with emphasis on histologic, immunohistochemical and prognostic factors

Retrospective canine skin peripheral nerve sheath tumors data with emphasis on histologic, immunohistochemical and prognostic factors

... retrospective study was determined the frequency of canine skin peripheral nerve sheath tumors (PNST) in cases diagnosed by the Setor de Patologia Veterinária of the ... See full document

10

Altered oxidative stress and carbohydrate metabolism in canine mammary tumors

Altered oxidative stress and carbohydrate metabolism in canine mammary tumors

... glucose-6-phosphatase and F-1, 6-bisphos- phatase in the liver of patients with breast ...observed in our study in canine mammary tumor tissues compared to normal ... See full document

4

Immunohistochemical evaluation of e-cadherin, Ki-67 and PCNA in canine mammary neoplasias: Correlation of prognostic factors and clinical outcome

Immunohistochemical evaluation of e-cadherin, Ki-67 and PCNA in canine mammary neoplasias: Correlation of prognostic factors and clinical outcome

... e-cadherin expression, which is considered a likely marker of favorable prognosis in the literature, showed a good expression in this ...between the low expression of ... See full document

9

Immunohistochemical expression of B and T-lymphocytes and TGF- βββββ in experimentally transplanted canine venereal tumor

Immunohistochemical expression of B and T-lymphocytes and TGF- βββββ in experimentally transplanted canine venereal tumor

... Although the lymphocytic infiltrate is considered to be a manifestation of the immune response against cancer, controversy regarding whether T cells have a central role in antitumor immunity still ... See full document

7

Expression of glutathione, glutathione peroxidase and glutathione S-transferase pi in canine mammary tumors

Expression of glutathione, glutathione peroxidase and glutathione S-transferase pi in canine mammary tumors

... PUBMED. The GCLC and GSS genes were selected because they synthesize GSH, and the gene GST-Pi was not used in this study because its sequence was not available for the ... See full document

10

Expression of betacatenin in carcinoma in pleomorphic adenoma, pleomorphic adenoma and normal salivary gland: an immunohistochemical study

Expression of betacatenin in carcinoma in pleomorphic adenoma, pleomorphic adenoma and normal salivary gland: an immunohistochemical study

... with the duration of proliferation and increasing tumor size, so that pleomorphic adenomas could represent an early (pre)malignant neoplastic lesion ...(13-16). The present mean size of ... See full document

5

Análise prognóstica da imunoexpressão de proteínas relacionadas à transição epitelial-mesenquimal nos carcinomas mamários esporádicos de cadelas

Análise prognóstica da imunoexpressão de proteínas relacionadas à transição epitelial-mesenquimal nos carcinomas mamários esporádicos de cadelas

... involved in the progression and metastasis of various cancers in humans, but this specific process is still little explored in the veterinary ...literature. The aim of ... See full document

92

Immunohistochemical study of genital and extragenital forms of canine transmissible venereal tumor in Brazil

Immunohistochemical study of genital and extragenital forms of canine transmissible venereal tumor in Brazil

... ages and sexes. In 10 dogs, the tumors were located in external genital mucosa and in 13 dogs the tumors had an extragenital location (7 skin, 4 oral ... See full document

5

Ligand-independent canonical Wnt activity in canine mammary tumor cell lines associated with aberrant LEF1 expression.

Ligand-independent canonical Wnt activity in canine mammary tumor cell lines associated with aberrant LEF1 expression.

... b-catenin and LEF1 knock down was performed in CMT-U27 ...resulted in a potent inhibition of TCF-reporter activity (Fig. 6C) and down regulation of Axin2 target gene ...on the ... See full document

12

Tumor-associated macrophage is correlated with survival and SOCS protein expression in canine mammary carcinoma

Tumor-associated macrophage is correlated with survival and SOCS protein expression in canine mammary carcinoma

... infiltrate in the tumor microenvironment, particularly in mammary tumors, has aroused great interest in oncology, to play different roles in the progression or ... See full document

9

Prevalence of the Prefoldin Subunit 5 Gene Deletion in Canine Mammary Tumors.

Prevalence of the Prefoldin Subunit 5 Gene Deletion in Canine Mammary Tumors.

... This study was intended to validate our earlier finding [5] on the presence of a recurrent somatic deletion of the PFDN5 gene on ...CFA27. The results confirm that this somatic deletion is ... See full document

10

Assessment of cell proliferation and prognostic factors in canine mammary gland tumors

Assessment of cell proliferation and prognostic factors in canine mammary gland tumors

... rapid and low cost method for the estimation of tumor cell proliferation (Weidner et ...Aranda and Laforga, 1997). In addition, some investigators have found mitotic figure content to be a ... See full document

10

MicroRNA and cancer: a focus on mammary tumors in female dogs

MicroRNA and cancer: a focus on mammary tumors in female dogs

... A study assessed the global miRNA expression profile in 146 samples of canine mammary tumors, including 30 benign samples, 116 malignant samples, and 25 normal ... See full document

6

Immunohistochemical and molecular expression of laminin-332 gamma-2 chain in canine mammary tumors

Immunohistochemical and molecular expression of laminin-332 gamma-2 chain in canine mammary tumors

... pure and undefined breed, aged from 2 to 17 years (mean age=10 ...animal. The fragments used in the molecular assays were frozen immediately after ...surgery. The fragments used ... See full document

8

Immunohistochemical detection of estrogen receptors in canine mammary tumors

Immunohistochemical detection of estrogen receptors in canine mammary tumors

... Mammary tumors are among the most common neoplasms in intact female ...age and older bitches. Almost 50% of the mammary tumors in dogs are malignant ... See full document

5

Retrospective review and systematic study of mammary tumors in dogs and characteristics of the extracellular matrix

Retrospective review and systematic study of mammary tumors in dogs and characteristics of the extracellular matrix

... cells and not in the extracellular matrix, may have an important role in the initial stages of condrometaplasia as a proliferation ...as an excellent cell marker for ... See full document

5

Ki-67 expression score correlates to survival rate in gastrointestinal stromal tumors (GIST)

Ki-67 expression score correlates to survival rate in gastrointestinal stromal tumors (GIST)

... recurrence, and distant metastasis – were evaluated by Fisher’s exact test or chi-squared 2 test as ...diagnosis and positivity for p53, p16, Bcl- 2 e Ki-67 were compared using t test and ... See full document

7

Embryonic stem cells are redirected to non-tumorigenic epithelial cell fate by interaction with the mammary microenvironment.

Embryonic stem cells are redirected to non-tumorigenic epithelial cell fate by interaction with the mammary microenvironment.

... of the mammary microen- vironment’s ability to reprogram embryonic cells that have not yet committed to a cell fate, and test the mammary gland’s capacity to alter the ... See full document

7

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