[PDF] Top 20 Mesenchymal stem cells secretome in Parkinson’s disease regenerative medicine

... role in pathogenesis of PD remains unclear (Dickson et al., 2009). However, in recent years, it has become clear that the initial sites displaying LBs are the dorsal motor nucleus of the vagus in the ... See full document

... proliferated in vitro, and after injection can be transferred to mid ...found in different areas of brain and brain stem such as the substantia nigra of midbrain, hypothalamus, some part of retina, ... See full document

... Mesenchymal stem cells (MSC) are multipotential nonhematopoietic progenitor cells capable of differentiating into multiple mesenchymal ...used in regenerative ... See full document

... iPS cells is currently challenging due to ethical, technological, and safety ...reasons. In addition to the potential development of teratomas after transplantation of pluripotent cells, in ... See full document

... improvements in wound regeneration, such as reduced healing time, in multiple tissues and in several species ...use in other mammals, specifically humans and dogs, which have been more ... See full document

... MSCs in the treatment of MS (Gerdoni et ...(EAE), in which immunization with neural antigens derived mainly from myelin, in combination with adjuvants, leads to demyelination, inflammation, and ... See full document

... of stem cell –based endodontic therapy (ie, pulp regeneration) is characterized by an empirical ...exist in this area that has the potential to create meaningful changes in endodontic therapy ... See full document

... the disease is dominated by an exacerbated inflammatory response (also called ‗cytokine storm‘) responsible for successive organ failures and ultimately refractory hypotension leading to shock ...process in ... See full document

... Bevan S, Blum B, Brooking J, Chen KG, Choo AB, Churchill GA, Corbel M, Damjanov I, Draper JS, Dvorak P, Emanuelsson K, Fleck RA, Ford A, Gertow K, Gertsenstein M, Gokhale PJ, Hamilton RS, Hampl A, Healy LE, ... See full document

... resuspended in Dulbecco’s Modiied Eagle’s Medium/Nutrient Mixture F-12 Ham (DMEM/F12) (Sigma-Aldrich) supplemented with 10% Fetal Bovine Serum (FBS) (Cultilab, Campinas-SP, Brazil), 100 U/ml penicillin (Sigma- ... See full document

... A hipótese de fusão é sustentada por experimentos que mostram a ocorrência de fusão espontânea entre ES e células-tronco neurais (Ying et al., 2002) ou células da medula óssea (Terada et al., 2000), quando co-cultivadas. ... See full document

... involved in MSCs characterization revealed consistent results with flow cytometric ...2 in comparison to group 1 and 3 (Figura 9b). From the factors measured in this study, IL2, IL6R, INFAC, INFB1, ... See full document

... R6/2) of HD, which were transplanted using the intra- cerebral route (directly into the striatum). hese stud- ies demonstrate that MSC transplantation leads to behavioral and memory improvements, reduced brain damage, ... See full document

... 76. Armstrong RB, Goldnick PD e Ianuzzo CD. Histochemical properties of skeletal muscle fibres in streptozotocin-diabetic rats. s.l.: Cell Tis Res 1975. n. 162, p. 387-394. 77. Baldwin KM e Haddad F. Effects of ... See full document

... Conejero et al. 6 utilizaram uma falha óssea crítica retangular na região do palato de ratos para comparar técnicas distintas de BTO. Os autores dividiram os animais em 4 grupos. No grupo controle, as falhas ósseas não ... See full document

... physiology[7,8,9]. In order to form protein-based hydrogels, genetically encoded proteins with multiple cross-linking sites are ...delivery, cells encapsula- tion, and cells ... See full document

... tract in the disease protein, resulting in the alteration of its conformation/physiological role and in the formation of toxic fragments/aggregates of the ...delay disease progression ... See full document

... TGFb in HCC tissue expression was up-regulated around MSCs at the edge of tumor or tumor stromal ...markers in HCC ...decrease in CFI in patients with down-regulation of E-cadherin ...shown ... See full document

... applied in soft tissue engineering, reinforcement of scaffolds is frequently necessary for hard tissue engineering due to their low mechanical ...problems in which a response of interest affected by several ... See full document

... An 85-year-old patient with stable Parkinson’s disease (PD), treated with levodopa/carbidopa 250/25 mg tid. During a follow-up visit, it was noticed that her temporal white hair was getting progressively darker ... See full document