Top PDF Metabolic constraint-based refinement of transcriptional regulatory networks.
Metabolic constraint-based refinement of transcriptional regulatory networks.
... reconstruct transcriptional regulatory networks (TRNs) focus primarily on proximal data such as gene co-expression and transcription factor (TF) ...reconstruction of TRNs, the overwhelming ...
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Iterative reconstruction of transcriptional regulatory networks: an algorithmic approach.
... logic of the interactions (Figure 1). The computa- tional component is based on dynamic growth simulations using regulated Flux Balance Analysis (rFBA), which is a constraints-based approach for ...
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Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms.
... investigation of TERT transcription using modelling to probe its regulation at the systems ...level of identification of individual transcrip- tion factor regulators of ...view of their ...
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A plasmid-based Escherichia coli gene expression system with cell-to-cell variation below the extrinsic noise limit
... gene regulatory networks ...inducible transcriptional repressor TetR-EGFP can reduce gene expression noise in Escheri- chia coli [6,7], which was suggested to result from dosage compensation for ...
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The regulation of sulfur metabolism in Mycobacterium tuberculosis.
... importance of the sulfate assimilation pathway to bacterial survival [6] and the hostile conditions encountered by bacteria in the phagosome ...deprived of essential nutrients ...upregulation of key ...
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Bioinformatics Analysis of the Effects of Tobacco Smoke on Gene Expression.
... the transcriptional regulatory network, the TFs f MAX and USF1 regulated many overlapped ...member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription ...expression ...
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Sox10 controls migration of B16F10 melanoma cells through multiple regulatory target genes.
... aspects of melanocyte biology some of which appear to be mutually in conflict ...differentiation of melanocytes has yet to be answered although the dosage effect has been proposed as a partial ...
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Functional alignment of regulatory networks: a study of temperate phages.
... the regulatory networks of two well-characterized temperate bacteriophages of ...classes of temperate bacteriophages: the lambdoid phages— which include k, P22, 434, HK97, and HK022, ...
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A parallel attractor-finding algorithm based on Boolean satisfiability for genetic regulatory networks.
... majority of human diseases is complex and caused by a combination of genetic, environmental and lifestyle factors, including cancer, Alzheimer’s disease, asthma, multiple sclerosis, osteoporosis, connective ...
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Deciphering the transcriptional-regulatory network of flocculation in Schizosaccharomyces pombe.
... cycles of alternating 2 min beating and 2 min incubation on ice with a Mini Beadbeater 16 (BioSpec Products, Bartlesville, ...bottom of the bead-beating vial with a flame-heated inoculating needle and ...
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Design of optimally constructed metabolic networks of minimal functionality.
... cardinality of these new MCS is smaller than the previously calculated ...classification of modes, which is computationally exhaustive if we use the conventional cMCS ...distribution of weights can ...
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Coordinate structures: constraint-based syntax-semantics processing
... number of scopings grows exponentially on the number of quantifiers in a ...total of 6 possible scopings, even though not all are equally ...explosion of semantic representations, but rather a ...
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Detection of dynamic spatiotemporal response to periodic chemical stimulation in a Xenopus embryonic tissue.
... response of AC explants to the frequency modulated stimulation is a hallmark of a diverse array of biological and physical ...Analysis of the response provides tremendous insight into ...
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A central role of abscisic acid in stress-regulated carbohydrate metabolism.
... identify regulatory components of salt stress signalling at the metabolite ...steps of salt stress-induced metabolic ...regulation of carbon flux or utilisation was identified upon salt ...
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Mestre em Engenharia Biológica
... consist of complex, intricate networks of a large number of genes, proteins, and ...part of larger networks comprising the environment as well as other cells or organisms ...
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J. Braz. Chem. Soc. vol.8 número5
... scheme of 2 are shown in ...atom of the ethylenediamine backbone, in the trans position with respect to the terminal oxo group, completes the coordination ...
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Evolutionary design of wireless sensor networks based on complex networks
... network based on complex network theory. We develop an heuristic approach based on genetic algorithms for finding a network configuration such that its communication structure presents complex network ...
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Evolutionary constraint helps unmask a splicing regulatory region in BRCA1 exon 11.
... skipping of exon 11 with a marked increase in amounts of the D(11) ...Overexpression of this isoform in mouse epithelial mammary cells has been shown to cause atypical duct hyperplasia ...a ...
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Why excluding H2O from metabolic networks?
... assistance of complex network theory, cellular metabolism has been widely investigated in the last decade (Jeong et ...function of complex metabolism network, as well as some practical application ...
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A local grid refinement technique based upon Richardson extrapolation
... These tech- niques often have been applied to the prediction of com- pressible flows using the full potential equation4 the Euler equation3 or the Navier-Stokes [r] ...
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