[PDF] Top 20 Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells
Has 10000 "Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells" found on our website. Below are the top 20 most common "Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells".
Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells
... of metformin effects on DNA mole- cules is ...thereby in- creasing nitric oxide synthase (Zhou et ...role in the gene regulation and signal transduction pathways possibly involved in ... See full document
6
Measuring DNA lesions induced by chemotherapeutic agents – DNA repair and DNA Damage
... reduction in cell viability when the exposed concentration rises from 100nM to 500nM of DOX, ranging from a percentages of 70% to 30% cell viability, ...observe DNA lesions without resulting in the ... See full document
66
Gene homozygosis and mitotic recombination induced by camptothecin and irinotecan in Aspergillus nidulans diploid cells
... of DNA synthesis and inducers of DNA strand breaks have been described as the most potent inducers of homologous recombination in mammalian cells (Arnaudeau et ...the DNA ... See full document
8
Rtt107 phosphorylation promotes localisation to DNA double-stranded breaks (DSBs) and recombinational repair between sister chromatids.
... their DNA that are either induced as a consequence of the action of exogenous agents, such as different drugs causing DNA damage, or as a consequence of the cell’s own metabolism, for instance ... See full document
11
RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells
... Efficient DNA repair in cancer cells is an important mechanism of therapeutic resistance, and inhibition of DNA repair pathway would be expected to make tumor cells more sensitive to ... See full document
11
Antimicrobial-induced DNA damage and genomic instability in microbial pathogens.
... errors in mitotic cell division, differences between eukaryotic mitosis and binary fission in prokaryotic bacteria, likely accounts for this phenomenon in eukaryotic path- ...both in the ... See full document
8
Actividade moduladora de extracto de Ginkgo biloba no ciclo celular de Saccharomyces cerevisiae e capacidade de reparação de danos de DNA em células sob stresse replicativo
... irradiation- induced oxidative organ injury in rats [70], protects against radiation-induced lethality, lipid peroxidation and DNA damage in humans [71], however, mechanisms of ... See full document
46
Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions
... pathways in mammalian cells. In NER, there are two subpathways that differ only in the recogni- tion of DNA damage, ...lesions in the transcribed strand of ... See full document
11
DNA DAMAGE INDUCED BY ACRYLAMIDE: ROLE OF GENETIC POLYMORPHISMS IN DNA DAMAGE LEVELS Marta Sofia Pereira Pingarilho Fazendeiro
... toxicity in cultured mammalian cells depleted of ...embryo cells induced by ...increases in the cytotoxicity of AA in HepG2 cells pre-treated with BSO [12], and ... See full document
229
Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer
... break DNA ends and does not require sequence homology. The first step in the process is the recognition of the DNA ends by the KU heterodimer composed by the KU70 and KU80 ...to DNA ends and ... See full document
13
Brown Flaxseed Prevents DNA Damage Induced by 1,2- Dimethylhydrazine in a Pre-Clinical Model
... blood cells and for the comet assay the collections were performed only on ...collection in the same way as the control ...collected in the same manner as described for the control ... See full document
13
Study of DNA damage induced by dental bleaching agents in vitro
... tissue damage from the contact of these agents with the oral mucosa. In the current study, the genotoxic potential associated with exposure to den- tal bleaching agents was assessed by the single cell gel ... See full document
5
Assessment of the DNA Damage in Human Sperm and Lymphocytes Exposed to the Carcinogen Food Contaminant Furan with Comet Assay
... of DNA damage of lymphocytes and sperm obtained after the treatment by furan are summarized in Figures 1-5 and and Table ...differences in DNA damage between the cell of ... See full document
8
Effects of melatonin on DNA damage induced by cyclophosphamide in rats
... embedded in 93 mL LMP agarose ...The cells were then lysed ...used in the comet assay because it recognizes the 8-OH guanine and formami- dopyrimidine that occur in spontaneous breaks ... See full document
9
Photodynamic DNA damage induced by phycocyanin and its repair in Saccharomyces cerevisiae
... due, in these cases, to an apoprotein protective action ...content in the reaction (20). In the type I reaction, there is a direct electron transfer from the photosensitizer to the DNA, while ... See full document
9
Regulation of nucleotide excision repair by nuclear lamin b1.
... arrest induced by LB1 silencing was accompanied by the induction of p53 and activation of ATR ...that DNA damage signaling or repair mechanisms might be defective ...detect DNA damage ... See full document
9
Protective effects of silymarin on methotrexate-induced damages in rat testes
... decreases in testicular weight, (Vardi et ...spermatogenic cells, particularly on spermatocytes and spermatids and reducing effects on the size of Sertoli and Leydig cells (Saxena et ...aberrations, ... See full document
10
Increased mammogram-induced DNA damage in mammary epithelial cells aged in vitro.
... that in vitro aged epithelial mammary cells are not as efficient as their young counterparts in recruiting 53BP1 after low-dose radiation ...of DNA damage required to trigger an ... See full document
10
The effects of anti-leukemia chemotherapy on LKB1-AMPK pathway functioning in acute myeloid leukemia cell lines
... exhibited in section 1.2.2 are inconclusive about the induction of DNA damage by cytarabine and/or doxorubicin in KG-1 cells, we decided to proceed with the analysis of AMPK ... See full document
129
DNA damage induces down-regulation of Prp19 via impairing Prp19 stability in hepatocellular carcinoma cells.
... involved in hepatocarcinogenesis. In normal human fibroblast, DNA cross- linking agent CDDP causes biophasic induction of Prp19, accompanied by p53 activation ...to DNA damage agents ... See full document
6
temas relacionados