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[PDF] Top 20 Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism.

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Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism.

Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism.

... in the amount of MTCO1 protein was detected by immunoblotting in whole cell lysates from mouse primary hepatocytes treated with metformin for 24 (data not shown) and 48 hours ...specific ... See full document

10

Bioenergetic cues shift FXR splicing towards FXR alpha 2 to modulate hepatic lipolysis and fatty acid metabolism

Bioenergetic cues shift FXR splicing towards FXR alpha 2 to modulate hepatic lipolysis and fatty acid metabolism

... relative expression of FXR splice variants affects its sum tran- scriptional activity and biological function ...[11,14,43]. Hepatic FXR a 2/ a 1 ratios are decreased in hepatocellular carcinoma ... See full document

12

Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning.

Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning.

... as energy sensors and regulate metabolic processes via their deacetylation ...activity. The sirtuin family consists of seven isoforms (SIRT1-7) that regulate distinct metabolic pathways in various ... See full document

9

Metformin Decouples Phospholipid Metabolism in Breast Cancer Cells.

Metformin Decouples Phospholipid Metabolism in Breast Cancer Cells.

... with metformin, [ 3 H]cho- line accumulation into PtdCho is increased indicating that alternative sources of fatty acids must be utilised by breast cancer cells treated with ...from the extracellular ... See full document

17

Bacterial Energy Metabolism Laboratory

Bacterial Energy Metabolism Laboratory

... are of extreme importance for life as they are the link to for energy conservation in living ...2011). The QmoABC complex is thought to exchange electrons with the ApsBA (APS reductase) ... See full document

210

Hepatic Macrosteatosis Is Partially Converted to Microsteatosis by Melatonin Supplementation in ob/ob Mice Non-Alcoholic Fatty Liver Disease.

Hepatic Macrosteatosis Is Partially Converted to Microsteatosis by Melatonin Supplementation in ob/ob Mice Non-Alcoholic Fatty Liver Disease.

... lished the food and weekly water intake values of these experimental ...indicate the general health condition of also melatonin treated experimental groups and underline that there are no side ... See full document

17

Selection of the temperature of casting the bronzes to plaster moulds

Selection of the temperature of casting the bronzes to plaster moulds

... to the temperature suita- bly: 1200 °C, 1180 °C, 1160 °C and 1140 °C, and then the mould was casted - probe TDAg and plaster mould with thin-walled, so- called casts test slats about dimensions: the ... See full document

6

New signalling pathways in reproductive tissues associated with mitochondrial dysfunction induced by metabolic diseases

New signalling pathways in reproductive tissues associated with mitochondrial dysfunction induced by metabolic diseases

... hundreds of mitochondria, with different sizes, shapes, and abundance depending on the cell ...type. The number of mitochondria in a cell is determined by the processes of ... See full document

85

The application of optical measurements for the determination of accuracy of gear wheels casts manufactured in the RT/RP process

The application of optical measurements for the determination of accuracy of gear wheels casts manufactured in the RT/RP process

... taking the measurements, an anti-reflection coating was applied on the tested gear ...wheel. The thickness of the coating ranged from 0,8 µm do 1,2 ...µm. The measurements were ... See full document

4

Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.

Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.

... for the indicated times. At the end of treatment, cells were washed with PBS and lysed in RIPA lysis buffer (50mM Tris-HCl, 1% IGEPAL, ...amount of protein from each lysate (* 50 μg) was ... See full document

26

Rev. Assoc. Med. Bras.  vol.51 número3

Rev. Assoc. Med. Bras. vol.51 número3

... 2. Bjorntorp P. Visceral O besity: a “civilization syndrome”. O bes Res 1993;1:206-22. 3. Ferrara CM, Lynch N A, N icklas BJ, Ryan AS, Berman DM. Differences in adipose tissue metabolism between postmenopausal and ... See full document

1

Energy Efficient Adaptive Protocol for Clustered Wireless Sensor Networks

Energy Efficient Adaptive Protocol for Clustered Wireless Sensor Networks

... divide the network into several clusters, each electing one node as its cluster ...head. The cluster-head collects data from sensors in the cluster which will be fused and transmitted to the ... See full document

6

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

... With the aim of minimizing the events set off by the muscle disuse, several techniques have been used, in an endeavor to improve the homeostatic conditions of the muscle ... See full document

7

A Method To Find The Area Of Sector Without The Usage Of Angle Made By The Chord

A Method To Find The Area Of Sector Without The Usage Of Angle Made By The Chord

... at the alternate sides, of the tangents through the diameter of the circle, and then the line joining these points divides the circle in the ratio of ... See full document

2

Erythropoietin reduces the expression of myostatin in mdx dystrophic mice

Erythropoietin reduces the expression of myostatin in mdx dystrophic mice

... member of the TGF family, is an important negative regulator of skeletal muscle mass ...(27). The deletion of the myostatin gene in the mdx mouse increases not only muscle ... See full document

6

Construction and analysis of the model of energy metabolism in E. coli.

Construction and analysis of the model of energy metabolism in E. coli.

... models of metabolism have only been analyzed with the constraint- based modelling philosophy ...models of diverse cellular processes have been generated and there have been several ... See full document

7

Bovine papillomavirus type 2 infection in the pathogenesis of the Bovine Enzootic Hematuria : related oncological process

Bovine papillomavirus type 2 infection in the pathogenesis of the Bovine Enzootic Hematuria : related oncological process

... infect the epithelia of vertebrates. They cause the development of exophytic tumors, papillomas, in their natural hosts and in some cases in related species (de Villiers et ...for the ... See full document

159

Gene expression profiling of mitochondrial oxidative phosphorylation (OXPHOS) complex I in Friedreich ataxia (FRDA) patients.

Gene expression profiling of mitochondrial oxidative phosphorylation (OXPHOS) complex I in Friedreich ataxia (FRDA) patients.

... quantification of the transcript levels of the genes encoding for the nDNA and mtDNA subunits of complex I and NDUFA4, a subunit from complex IV, was investigated using real ... See full document

10

The participation of the Ech and HynAB hydrogenases in the energy metabolism

The participation of the Ech and HynAB hydrogenases in the energy metabolism

... in the energy metabolism when lactate is the electron ...gene expression of this enzyme is among the top 15% of expressed genes during lactate/sulfate growth and it ... See full document

277

Comparative genome-centric analysis reveals seasonal variation in the function of coral reef microbiomes

Comparative genome-centric analysis reveals seasonal variation in the function of coral reef microbiomes

... characterisation of microbial community variation following environmental perturbation, the effect on microbiome function is poorly ...sequencing of sponge, macroalgae and seawater microbiomes from a ... See full document

16

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