[PDF] Top 20 MicroRNA-dependent regulation of transcription in non-small cell lung cancer.

... Squamous cell lung cancer (SCC) and adenocarcinoma are the most common histological subtypes of non-small cell lung cancer (NSCLC), and have been ... See full document

... PFS of advanced NSCLC patients receiving first-line platinum-based ...effect of the polymorphism was also apparent in subgroup of > 58 years old, male, ever smokers, never smokers, stage ... See full document

... inflammation, cancer can induce local or systemic inflammation, which is mediated by activation of transcription factors and production of major inflammatory cyto- kines ...hand, ... See full document

... expression of p-AKT and overall survival were ...because of insufficient data for ...titles of the publications and the abstracts to find exactly those articles that examined the relationship between ... See full document

... characteristics of cancer, such as cell differentiation, aggressiveness, invasion, angiogenesis, and metastatic behavior ...targets of p53 and their expression induces cell cycle arrest ... See full document

... variations in abundance of microRNA biomarkers reported in the literature might be a result of the inclusion of haemolyzed samples ...effect of haemolysis, the samples ... See full document

... observation of the presence of extracellu- lar nucleic acids in humans ...found in cell-free nucleic acids isolated from all different body fluids ...found in tumor cells can ... See full document

... ushered in a new era with respect to the treatment of advanced non-small-cell lung ...role in the improvement of outcomes in a metastatic ...The ... See full document

... proximity of the +61G locus to a region involved in EGF gene ...regulation. In September 2011, at the European Multidisciplinary Cancer Congress, in Stockholm, the association ... See full document

... reduction of complications derived from tumor biopsies, the possibility to anticipate progression and even the reduction of healthy costs with ambulatory non-invasive ...biomarkers in NSCLC. ... See full document

... action in non-small cell lung carcinoma (NSCLC) is not fully ...role in NSCLC tumor growth, NCI-H292 lung mucoepidermoid carcinoma cells and endothelial cells were ... See full document

... understanding of regulatory T cells (Treg) significantly improves our knowledge of immune system evasion and how it enables tumor ...expression of FOXP3; as a marker for Treg, is decreased in ... See full document

... mg of pure compound 2 (R f : ...mg) of fractions eluted with n-hexane/CH 2 Cl 2, 80:20 to ...mg of 1 (R f : ...mg of 2. Purification of the mother liquor residue of 1, by ... See full document

... a small molecule tyrosine kinase inhibitor that blocks all FGF, PGDF, and VEGF ...effects in a number of preclinical models of NSCLC and in NSCLC patients [14, ...lymphangiogenesis ... See full document

... deamination in double-stranded regions. Dysregulation of adenosine to inosine editing in human cancers potentially contributes to the altered transcriptional program necessary to sustain ... See full document

... involvement of mediastinal lymph nodes, as well as the detection of pleural effusion and/or pleural implants or distant metastatic disease, usually precludes radical surgical proce- ...selection of ... See full document

... result of increased cytotoxicity, but rather were mediated through immunological ...stimulator of T-Cells and has been used as a tumor vaccine in a variety of tumor types [21,33] Chemotherapy ... See full document

... Formation in H292 Cells Plasma membrane protrusions called filopodia increase during cell movement, and the formation of filopodia is involved in cancer cell migration and ... See full document

... Against Cancer e em 1974 foi publicado um sistema TNM modificado, com intuitos predominantemente clínicos ...no Lung Cancer Staging Project promovido pela IASLC, originou sucessivas revisões que ... See full document

... mutations in the EGFR gene respond better to treatment with EGFR tyrosine kinase ...pathway in smokers, their pre- valence has been reported to be similar in smokers and nonsmokers; however, ... See full document