[PDF] Top 20 The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5.

... investigate the molecular mechanism of the tumor suppressor role of miR-217 in GC, we used luciferase reporter assay and western blot to confirm that GPC5 was a target of ... See full document

... roles in tumor ...involved in a variety of biological functions, particularly ...regulate the expression of NRP1. The goal of this study was to identify miRNAs that could inhibit ... See full document

... involved in a variety of biological signaling pathways ...between tumor cells and cells derived from normal tissues, indicating that microRNAs have played important roles in tumorigenesis ...or ... See full document

... Gastric cancer is one of the most common malignancies and the second most frequent cause of cancer-related death ...has the highest incidence in China, Japan, Korea and ... See full document

... miR-26a in cancer cells seemed controversial in previous ...now, the role of miR-26a in gastric cancer remains ...undefined. In this study, we found that miR-26a ... See full document

... is the gene for non-muscle myosin heavy chain IIA (NMHCIIA), whose mutations are responsible for a complex disorder named MYH9-related disease, characterized by a combination of different phenotypic ... See full document

... shown in this report, we analyzed the expression of miR-219- 2-3p in 113 GC patients and found that the levels seem to be lower in ...function in GC remains to be ...miR-219-2-3p ... See full document

... involves the usage of specially designed drugs to selectively target molecular pathways correlated with the malignant pheno- type of lung cancer cells, may be more useful ...mutated in various ... See full document

... of the p53-induced genes (476/995), less than 10% of the repressed genes (13/221) contained a p53 binding peak in the vicinity ...S2). In two repressed genes a p53 binding peak mapped ... See full document

... of the microRNA (miRNA) processing genes Gemin3 and Gemin4 on cellular signaling pathways could have a major impact on the risk of ...concerning the association between the Gemin3 ... See full document

... of the TP53 tumor suppressor gene is believed to contribute to the develop- ment of the majority of human cancers ...(47,48). The TP53 gene is located on chro- mosome ...spanning ... See full document

... For in vitro and in vivo applications, AuNPs should be stabilized against aggregation induced by biological ...is the most frequently used macromolecule since it was the advantage to be ... See full document

... link the complex to the ...and the structure and signaling provided by the complex ultimately determines the cellular phenotype and behavior ...of the Wnt signaling ... See full document

... of the treatment options available to a patient with CV risk factors and known metastatic ...to the high rate of thromboembolic events with oral oestrogen, it has somewhat been abandoned as a ...therapy. ... See full document

... to the putative target sequence by cloning the regions containing human MUC4 and MUC16 coding sequences into the pMIR-Luciferase reporter vector (pMIR-MUC4 and MUC16 ...produced in ... See full document

... on the Association between IL10 Genetic Variants and the Risk of Advanced Atrophy and Intestinal Metaplasia in the Antrum and Body of the ...evaluated the associations between ... See full document

... a potential target of miR-203 ...assay in HEK293T cells. The results showed that transfection of miR-203 mimics significantly inhib- ited the expression of WT but not Mut 3’-UTR of ZNF217 ... See full document

... of the s / l interface of non-faceted phase lamellae where instability develops or vanishes and branching of faceted phase lamellae is ...on the existence of a whole spectrum of interlamellar spacings, O . ... See full document

... resected gastric tumors and are the most common submucosal mass found in the ...is the best and only option on most ...location. The reported case led us at literature review ... See full document

... to the N-terminal Thr residue of the b1 subunit within the 26S proteasome ...used the oncogenic v-Src as a positive control in these experiments since its effect on Dok1 stability ... See full document