[PDF] Top 20 MicroRNA-143 inhibits cell growth by targeting ERK5 and MAP3K7 in breast cancer
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MicroRNA-143 inhibits cell growth by targeting ERK5 and MAP3K7 in breast cancer
... for ERK5 and MAP3K7 BC tissues, noncancerous tissues and NC breast tissues were fixed in 4% ...dewaxed and dehydrated in xylene and gradient ethanol, ... See full document
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MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression.
... tumor growth and metastasis in vivo, we utilized xenograft models by injection of MDA-MB-435s cells, with forced expression of miR-7, orthotop- ically in the mammary fat pad of nude ... See full document
12
miR-26a suppresses tumor growth and metastasis by targeting FGF9 in gastric cancer.
... expression by causing degradation of target mRNAs, inhibition of the translation of these mRNAs or both ...part in crucial cellular processes such as the stress response, development, differentiation, ... See full document
10
HET0016, a selective inhibitor of 20-HETE synthesis, decreases pro-angiogenic factors and inhibits growth of triple negative breast cancer in mice.
... plasminogen inhibits EC proliferation and metastatic tumor cell growth ...plasminogen by a series of enzymes from the tumor environment, including the MMPssuch as MMP-2, MMP-7, MMP-9, ... See full document
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E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320a.
... E2A in normal B and T cell development and leukemogenesis has been well studied [13,30,31] and it was also demonstrated to be involved in breast cancer, prostate ... See full document
10
MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor.
... Slit and is conserved in animals ranging from fruit flies to ...mammals. In mammals, three Slit (Slit1–3) and four Robo (Robo1–4) genes have been described ...axons and growth ... See full document
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Cantharidin suppressed breast cancer MDA-MB-231 cell growth and migration by inhibiting MAPK signaling pathway
... pathway in breast ...p38, and JNK with each member having several isoforms: ERK1 to ERK8; p38a (MAPK14), p38 (MAPK11), p38g (MAPK12), and p38d (MAPK13); and JNK1 (MAPK8), JNK2 (MAPK9), ... See full document
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Propofol inhibits lung cancer cell viability and induces cell apoptosis by upregulating microRNA-486 expression
... miR-486 in cancers has been extensively ...miRNA in many cancers such as breast cancer (27), HCC (28), and gastric cancer ...downregulated in lung tumors compared with ... See full document
7
MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer.
... characterized by a combination of different phenotypic features ...expressed in most cells and tissues. Its functions include roles in cytokinesis, cell motility, and maintenance ... See full document
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Silencing of the hTERT gene by shRNA inhibits colon cancer SW480 cell growth in vitro and in vivo.
... revolution in somatic cell genetics, allowing the inexpensive and rapid analysis of gene function in mammals, as well as screening for gene therapy targets to treat ...disease. In fact, ... See full document
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MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression.
... roles in tumor ...involved in a variety of biological functions, particularly ...the growth, invasion and metastasis of gastric cancer by targeting NRP1 ...reduced ... See full document
11
ING1 and 5-azacytidine act synergistically to block breast cancer cell growth.
... ING1b and ING2 proteins differentially induce cell death and apoptosis in breast cancer cell lines compared to normal breast epithelial ...seen in cells that ... See full document
12
Association of PKCζ expression with clinicopathological characteristics of breast cancer.
... pathological and prognostic characteristics, including clinical stage, lymph node metastasis status, tumor size, HER2 status and survival ...studies in which transcript levels were ...overexpressed ... See full document
6
miR-126-3p Inhibits Thyroid Cancer Cell Growth and Metastasis, and Is Associated with Aggressive Thyroid Cancer.
... miR-126-3p in thyroid cancer cells, and as a marker of disease ...lower in larger tumors, in tumor samples with extrathyroidal invasion, and in higher risk group thyroid ... See full document
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Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways.
... mice and treated with embelin. Cell proliferation and apoptosis were measured by Ki67 and TUNEL staining, ...Akt, and Sonic Hedgehog (Shh) and their target gene products ... See full document
10
Synthesis and cytotoxic evaluation of a series of 2amino against human cancer cells
... carcinoma) and PC3-M (prostate) cancer cells and also against PBMC (peripheral blood mononuclear ...human cancer lines used in this ...cytotoxicity and selectivity against all ... See full document
12
MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA.
... that in primary follicles, miR- 181a expression was reduced in preantral follicles, where granulosa cell proliferation was activated, whereas acvr2a expres- sion was abundant in them ...cells ... See full document
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Cell Surface GRP78 Accelerated Breast Cancer Cell Proliferation and Migration by Activating STAT3.
... of breast cancer (Fig 1D and Table 1), suggesting that sGRP78 might contribute to breast cancer ...supported by our in vitro studies. Human MCF-7 breast ... See full document
17
MicroRNAs in lung cancer
... Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed ...affected by this ...of microRNA alterations ... See full document
7
The Complex Link between Apoptosis and Autophagy: a Promising New Role for RB
... defects in the pathways that regulate its phosphorylation rather than by ...differentiation and cell cycle, but also, more recently for apoptosis and ...findings in the ... See full document
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