[PDF] Top 20 miR-127 regulates cell proliferation and senescence by targeting BCL6.
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miR-127 regulates cell proliferation and senescence by targeting BCL6.
... that BCL6 expression was up-regulated in breast tumors compared with their corresponding tumor-adjacent tissues (Figure ...lower, and BCL6 expression is higher than in adjacent normal tissues, ... See full document
9
E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320a.
... cells, and CRC cancer cells, loss of E2A led to enhanced proliferation ...inhibited cell growth of T cell ALL ...cancer cell proliferation, we constructed an E2A stably ... See full document
10
Upregulated microRNA-92b regulates the differentiation and proliferation of EpCAM-positive fetal liver cells by targeting C/EBPß.
... pancreatic cell line AR42J-B13, researchers showed that transfection with C/EBP-bprovoked hepatic differentiation [36], while transfection with a dominant negative inhibitor of C/ EBP-b will both inhibit ... See full document
14
Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R.
... gastric and colorectal carcinomas. miR- 150 appears, however, to have pleiotropic effects on malignant ...Enhanced miR-150 expression promotes gastric carcinoma cell proliferation while ... See full document
11
MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression.
... whether miR-7 regulates tumor growth and metastasis in vivo, we utilized xenograft models by injection of MDA-MB-435s cells, with forced expression of miR-7, orthotop- ically in the ... See full document
12
MicroRNA-450a-3p represses cell proliferation and regulates embryo development by regulating Bub1 expression in mouse.
... (TargetScan and miRanda) were used to identify putative miRNAs that could bind to the 3 9-UTR of ...vectors and miRNA- mimics were co-transfected into HEK 293 ...suppressed by 54% (p ,0.001) in HEK ... See full document
8
IGF-1 regulates Cyr61 induced breast cancer cell proliferation and invasion.
... prognosis and outcome in women with breast cancer, upregulates Cyr61 through both the MAPK and PI3K/Akt pathways resulting in cell invasion and growth (Figure ...mediated cell invasion ... See full document
11
Matrix stiffness regulates endothelial cell proliferation through septin 9.
... cells and influence cellular functions including proliferation and ...hypertension, and diabetes [1– ...permeability and homeostasis, and their dysfunction, such as inflammation ... See full document
13
Shaofeng Yang, Nan Sheng, Lili Pan, Jing Cao, Jiao Liu and Ran Ma
... PBS and then lysed with 1 sodium dodecyl sulfate (SDS)-loading buffer (50 mM Tris-Cl, pH ...UK), and pRb (#9313; Cell Signaling Technology, ...developed by enhanced chemiluminescence ... See full document
9
ANKHD1 regulates cell cycle progression and proliferation in multiple myeloma cells
... the cell lines with almost complete inhibition of expression in U266 ...in cell cycle progression as cyclin A regulates S/G2 progression but its upregulation in U266 could not be explained requiring ... See full document
8
MicroRNA-455 suppresses the oncogenic function of HDAC2 in human colorectal cancer
... washed by phosphate- buffered saline (PBS) and then were treated according to the manufacturer’s protocol of RIPA lysis buffer (Beyotime, ...measurement by BCA assay kit (Pierce, USA), equal amounts ... See full document
7
Rui Xiang, Han Lei, Mianzhi Chen, Qinwei Li, Huan Sun, Jianzhong Ai, Tielin Chen, Honglian Wang, Yin Fang and Qin Zhou
... The miR-17-92 cluster expres- sion construct was generated by using PCR to amplify a 1102-bp fragment encoding the mir-17-92 cluster precursor from mouse genomic DNA with the forward primer: 5’-GTC ... See full document
9
Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα.
... suppressed by miR-221 and miR-222-3p ...that miR-222-3p also inhibits ERa expression in EC cell ...that miR-222-3p inhibited ERa expression at both protein and mRNA ... See full document
12
In the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafish.
... 2/2 and p53 2/2 shh 2/2 mutant embryos were stained for markers of retinal cell ...ganglion and amacrine cells in the wild-type ...ganglion and amacrine cells were labelled ...identified ... See full document
18
Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a.
... Cip1 and cyclin D1 levels by miR-96 are caused by the regulation of ...of miR-96 (Figure 4A). As predicted, ectopic expression of miR-96 in MCF-7 and ZR-75- 30 cells ... See full document
10
miR-379 regulates cyclin B1 expression and is decreased in breast cancer.
... post-transcriptionally, and are known to be altered in many diseases including breast ...of miR-379 in breast cancer. miR-379 expression was quantified in clinical samples including tissues from ... See full document
7
MiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1.
... 6 and 8 Gy, Nasatron (Cs-137) ...PBS and stained with crystal violet ...calculated by normalisation to the plating efficiency of appropriate control ...fit cell survival curve in accordance ... See full document
9
Coordination of cell proliferation and cell fate determination by CES-1 snail.
... elegans and during the analysis of the NSM (NSM, neuro-secretory motoneu- ron) lineages (Two bilaterally symmetric NSM lineages exist, the left and right NSM ...sizes and different cell fates, ... See full document
16
TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1.
... TBK1) and TRIM11 or empty vector, and then used to treat Vero cells prior to viral infection with HSV-1 or ...determined by quantitative RT- PCR. Consistently, IFNb mRNA increase in MAVS- and ... See full document
12
Clinics vol.68 número5
... hsa-miR-100 and hsa-miR-218 ...C and 4 ˚ C until ...System and a Taqman Universal PCR Master Mix (Applied Biosystems, Foster City, ...assessed by relative quantification, ... See full document
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