[PDF] Top 20 Noncanonical inflammasomes: caspase-11 activation and effector mechanisms.
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Noncanonical inflammasomes: caspase-11 activation and effector mechanisms.
... The noncanonical inflammasome pathway has been shown to be activated by a range of different Gram-negative bacteria but not by Gram-positive bacteria, suggesting that it is a conserved mechanism for the detection ... See full document
4
Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.
... Inflammasome activation is important for antimicrobial defense because it induces cell death and regulates the secretion of IL-1 family cytokines, which play a critical role in inflammatory ...activates ... See full document
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A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.
... inflammation and apoptosis ...metazoans, and their conversion to the active enzyme is tightly controlled by many different signaling ...of caspase regulation have focused on activator proteins, such ... See full document
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Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways.
... (MTT) and propidium iodide (PI) were purchased from Wako Pure Chemical Industries, ...Medical and Biological Laboratories Co., Ltd. (Nagoya, Japan). Rh123 and - Cellstain H- Hoechst 33342 were ... See full document
14
Antioxidant dietary deficiency induces caspase activation in chick skeletal muscle cells
... pared and analyzed as described (16), with the following modifications: cells were lysed in 10 mM Tris buffer, pH ...PMSF and 2% SDS for 1 h at 42ºC, and centrifuged at 14,000 rpm for 20 ...5.2, ... See full document
7
Infections with avian pathogenic and fecal Escherichia coli strains display similar lung histopathology and macrophage apoptosis.
... kidneys, and spleens at 24 h post-infection ...18, and 24 h p.i. Serial lung sections were stained with hematoxylin and eosin (HE), terminal deoxynucleotidyl dUTP nick end labeling (TUNEL) for ... See full document
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A preliminary investigation into the impact of a pesticide combination on human neuronal and glial cell lines in vitro.
... stress and/or reduction in ATP ...cyprodinil and pyrimethanil directly impaired the expression of a major antioxidant defence enzyme (GSHPx) at low and high concentra- tions, whilst negatively ... See full document
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O PAPEL DO INFLAMASSOMA NLRP3 E CASPASE 111 NA MODULAÇÃO DA ADIPOGÊNESE, INFLAMAÇÃO E MICROBIOTA
... o Independentemente da obesidade, os animais Caspase 1/11 -/- apresentaram aumento de moléculas apresentadores de antígenos lipídicos (CD1d) em células do lavado peritoneal.[r] ... See full document
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Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection.
... consistent and may provide the mechanistic basis that explains the relative immune suppression previously observed during this infection ...viral and parasitic pathogens ...changes, and ... See full document
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ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... apoptosis and autophagy were ...activated caspase-3 or -9, consistent with the presence of caspase ...of caspase-9, -6 or -3 prevented cell death (100 µM Ac-LEDH-CHO, 50 µM Ac-VEID-CHO ... See full document
8
E. adenophorum Induces Cell Cycle and Apoptosis of Renal Cells through Mitochondrial Pathway and Caspase Activation in Saanen Goat.
... apoptosis and cell cycle arrest, suggesting that renal cells was sensitive to ...protein and mRNA levels, and pro- moted the translocation of Bax from cytoplasm to mitochondria and that of Cyt ... See full document
16
Cinnamomum cassia Suppresses Caspase-9 through Stimulation of AKT1 in MCF-7 Cells but Not in MDA-MB-231 Cells.
... expression and its consequent effect on caspase-9 suppres- sion, MCF-7 cells do not show a considerable difference in mortality in response to ...[35]. Caspase-8, upon activation, would ... See full document
22
Imbalanced expression of functional surface molecules in regulatory and effector T cells in systemic lupus erythematosus
... Several pieces of evidence indicate that deficiency or dysfunction of TREG cells produced by genetic abnormal- ities or environmental insults, even for a short period of time, could be sufficient to trigger autoimmunity ... See full document
8
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... urgent need to reverse the ionic imbalance in a child with a Glasgow coma score of 8 led to the performance of hemodiailtration. It has been reported that parathyroid hormone related peptide (PTHrp) is an important ... See full document
2
Stabilization of Nrf2 protein by D3T provides protection against ethanol-induced apoptosis in PC12 cells.
... skeletal and connective tissues of the face ...the mechanisms underlying D3T- mediated Nrf2 activation and subsequent protection against ethanol-induced apoptosis in neural crest cells ... See full document
5
Role of astrocytes in an in vitro model of ischemic stroke
... subacute and chronic phases of IS has not brought enough results ...ischemia and consequent improvement of functions regulated by those areas ...pathophysiological mechanisms of IS are well known ... See full document
216
Lymphocyte Differentiation and Effector Functions
... lymphocytes and its products range from the neutralization of pathogens with specific antibodies to the activation of macrophages and to direct cytotoxic ...(BCR and TCR, resp.,), which are ... See full document
4
AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis.
... the activation of STING leading to unabated pro- duction of type I IFNs and pro-inflammatory cytokines ...IL-6 and IL-1β ...others and thereby greatly ameliorates disease progression ... See full document
14
Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain.
... exercise, and cognitive training represent a quietly emerging revolution in the modern approach to counteracting age-related declines in brain ...antioxidants and mitochondrial cofactors (AOX) or behavioral ... See full document
10
Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells.
... protein and ASC protein, indicating the activation of Figure ...GRP78 and the phosphorylation of eIF2a in NRK-52E cells after treatment without or with 5 mg/ml BSA for various time periods in ... See full document
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