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Synthesis Characterization and Antimicrobial studies of some Novel Sulphonamides containing Substituted Naphthofuroyl group

Synthesis Characterization and Antimicrobial studies of some Novel Sulphonamides containing Substituted Naphthofuroyl group

... 5-Substituted-naphtho[2,1- b ]furan-2-carboxylic acids (3a- c): 2-Ethyl naphtho[2,1-b]furan 2-carboxylate was dissolved in methanol and mixed with 10% NaOH solution. The mixture was refluxed for 2h. After the ...
Synthesis, characterization and comparative antimicrobial studies of some novel chalcones and pyrazolines containing naphthofuryl substituents

Synthesis, characterization and comparative antimicrobial studies of some novel chalcones and pyrazolines containing naphthofuryl substituents

... The formation of alcohol (2a-b) from ester (1a-b) was confirmed by mass, IR and NMR. In the mass spectrum of 2a, the molecular ion peak appeared at m/z 197. The IR spectrum of 2a has shown broad absorption band ...
Study on the Synthesis, Characterization and Antimicrobial studies of the Transition Metal Complexes of the Novel Mannich Base Derived from Pyridazine Derivative

Study on the Synthesis, Characterization and Antimicrobial studies of the Transition Metal Complexes of the Novel Mannich Base Derived from Pyridazine Derivative

... literature studies revealed that Mannich bases are very reactive and can be easily converted to other compounds, for example, reduced to form physiologically active amino alcohols 1 ...
SYNTHESIS, CHARACTERIZATION AND STUDY OF ANTIMICROBIAL AND ANTIFUNGAL ACTIVITIES OF SOME NOVEL PYRIMIDINE DERIVATIVES

SYNTHESIS, CHARACTERIZATION AND STUDY OF ANTIMICROBIAL AND ANTIFUNGAL ACTIVITIES OF SOME NOVEL PYRIMIDINE DERIVATIVES

... 5- substituted thiouracils possess chemotherapeutic activity against cancer cells as well as antifungal, antiviral and antiparasitic ...cancerostatic. Studies have shown that arylazo groups are active in ...
Synthesis, Characterization, and in silico Studies of Novel Alkanoylated 4-‎Methylphenyl sulphonamoyl Carboxylic Acids as Potential Antimicrobial and ‎Antioxidant Agents

Synthesis, Characterization, and in silico Studies of Novel Alkanoylated 4-‎Methylphenyl sulphonamoyl Carboxylic Acids as Potential Antimicrobial and ‎Antioxidant Agents

... functional group are crucial in medicinal chemistry for the design of drugs with a broad spectrum of biological ...Industrially, sulphonamides are useful in the production of some health products, ...
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME 2-SUBSTITUTED BENZOTHIAZOLES CONTAINING AZOMETHINE LINKAGE

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME 2-SUBSTITUTED BENZOTHIAZOLES CONTAINING AZOMETHINE LINKAGE

... ongoing studies in developing new antimicrobials, a novel series of N-(1, 3-benzothiazol-2-yl)- 2-[(2Z)-2-(substituted arylidene) hydrazinyl] acetamide (5a–j) was synthesized in order to determine ...
Novel synthesis and spectral characterization of some new substituted pyrazolones and isoxazolone

Novel synthesis and spectral characterization of some new substituted pyrazolones and isoxazolone

... of some new substituted pyrazolone derivatives containing different functional groups have been synthesized by the condensation reaction of 2-methoxy-5-methyl ethyl aceto hydrazone (1a) and different ...
Synthesis, Spectral, Theoretical, Antimicrobial Evaluation, and Molecular Docking Studies of Some Novel Ethyl 5 (1 Methyl 1h Tetrazol 5 Ylthio) 4 Oxo 2,6 Substituted Diphenylpiperidine 3 Carboxylate Derivatives

Synthesis, Spectral, Theoretical, Antimicrobial Evaluation, and Molecular Docking Studies of Some Novel Ethyl 5 (1 Methyl 1h Tetrazol 5 Ylthio) 4 Oxo 2,6 Substituted Diphenylpiperidine 3 Carboxylate Derivatives

... preparation, characterization and pharmacological evaluation of bis heterocycles containing piperidine moiety in combination with N- ...the synthesis is shown in Scheme ...
Novel Synthesis, Characterization and Antimicrobial Activity of Some Nitrogen Containing Heterocyclic Moiety

Novel Synthesis, Characterization and Antimicrobial Activity of Some Nitrogen Containing Heterocyclic Moiety

... A series of 3-[(2,4-Dinitro phenyl)-(substituted amino)-1-ylmethyl-amino]-2-substituted phenyl-5-(3,4,5-trimethoxy benzylidene)-3,5-dihydro-imidazol-4-one derivatives were synthesized by the condensation of ...
Molecular Docking studies and in-silico ADMET Screening of Some novel Oxazine substituted 9-Anilinoacridines as Topoisomerase II Inhibitors

Molecular Docking studies and in-silico ADMET Screening of Some novel Oxazine substituted 9-Anilinoacridines as Topoisomerase II Inhibitors

... clinically useful DNA-intercalating agents involves the inhibition of the enzyme DNA- topoisomerase I or II. Several detailed SAR studies of acridine-based DNA-intercalating agents suggest that the mode of binding ...
Synthesis, Characterization and Antimicrobial Activity of Some New Substituted Quinoline Hydrazones

Synthesis, Characterization and Antimicrobial Activity of Some New Substituted Quinoline Hydrazones

... the synthesis of different heterocyclic scaffolds such as 1, 3, 4-oxadiazolines, azetidin-2-ones, coumarins, 1, 3-thiazolidin-4-ones and 1,3-benzothiazin-4-ones ...activities. Some widely used antibacterial ...
Synthesis and Characterization of Novel Schiff base Cu(II) Complexes: Antimicrobial and Molecular docking Studies

Synthesis and Characterization of Novel Schiff base Cu(II) Complexes: Antimicrobial and Molecular docking Studies

... The antimicrobial activity of the ligand and itsCu(II) metal complexes were assayed against Gram- positive and Gram-negative ...of antimicrobial activity are summarized in Table 3 and ...
Synthesis, Characterization and Pharmacological Studies of Some Substituted Fluoroquinolones

Synthesis, Characterization and Pharmacological Studies of Some Substituted Fluoroquinolones

... N-1 substituted fluoroquinolonic derivatives were synthesized and evaluated for antimicrobial and antioxidant ...sulphonyl substituted derivatives of the title compounds have been synthesized to ...
Synthesis and antimicrobial studies of some novel pyrazolines

Synthesis and antimicrobial studies of some novel pyrazolines

... Antimicrobial screening of synthesized pyrozolines compounds (I-X) was conducted by using cup plate method [20-21] at a concentration of 100µ g/ml. The compound were evaluated for antibacterial activity against ...
Novel synthesis, characterization and antimicrobial activity of some new 3, 5-diarylpyrazolines

Novel synthesis, characterization and antimicrobial activity of some new 3, 5-diarylpyrazolines

... M.Ps. reported are uncorrected and were recorded on ‘Tempo’ melting point apparatus. The purity of the compounds synthesized was tested by TLC on microscopic slides with silica gel-G layers. The Infra red spectra were ...
Synthesis and Antimicrobial Activity of Some Novel Pyrazolones

Synthesis and Antimicrobial Activity of Some Novel Pyrazolones

... ring. PMR spectrum of the compound exhibited signals of propyl side chain, a triplet at d1.04 due to methyl group, sextet for methylene at d1.77 and triplet at d 2.68 for another methylene. Compound 2g, in its IR ...
Synthesis and Screening of Biological Activities of Some Important Pyrazoline Derivatives

Synthesis and Screening of Biological Activities of Some Important Pyrazoline Derivatives

... The newly synthesized pyrazoline derivatives exhibited moderate to promising antimicrobial activity against standard strains. This class of compounds certainly holds great promise to discover novel classes ...
SYNTHESIS, SPECTRAL STUDIES AND ANTIMICROBIAL SCREENING OF SOME TRANSITION METAL COMPLEXES WITH SUBSTITUTED ACETOPHENONE THIOSEMICARBAZONE

SYNTHESIS, SPECTRAL STUDIES AND ANTIMICROBIAL SCREENING OF SOME TRANSITION METAL COMPLEXES WITH SUBSTITUTED ACETOPHENONE THIOSEMICARBAZONE

... of substituted acetophenone with thiosemicarbazone in the presence of hot ...as antimicrobial, antifungal, antiviral, insecticides, and antitumor ...
Synthesis and characterization of novel benzothiophene substituted oxadiazole derivatives and their antimicrobial activity

Synthesis and characterization of novel benzothiophene substituted oxadiazole derivatives and their antimicrobial activity

... benzothiophene substituted 1,3,4-oxadiazole derivatives substituted at 2 and 5 positions were synthesized and evaluated for their antibacterial and antifungal ...
Synthesis, characterization and antimicrobial activity of some novel chalcones

Synthesis, characterization and antimicrobial activity of some novel chalcones

... invitro antimicrobial activity of test compounds were assessed against 24 hr cultures of several selected bacteria and ...The antimicrobial activity was performed by broth dilution method in ...

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