[PDF] Top 20 LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition.
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LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition.
... Breast cancer has been classified into four subtypes based on gene expression profile ...[12]. Basal-like breast cancer, one of the subtypes, does not display hormonal receptors ... See full document
12
Low serum 25-hydroxy vitamin D levels are associated with aggressive breast cancer variants and poor prognostic factors in patients with breast carcinoma
... A and luminal B were grouped as luminal type breast ...neu and basal-like groups were classified as non-luminal breast ...cancer. Like other study results, patients ... See full document
8
HP1β is a biomarker for breast cancer prognosis and PARP inhibitor therapy.
... techniques to determine if the expression level of HP1β/CBX1 mRNA was associated with the outcome of breast cancer patients using a published microarray dataset [23, ...mRNA is ... See full document
17
Decreased expression of the FOXO3a gene is associated with poor prognosis in primary gastric adenocarcinoma patients.
... apoptosis, and DNA damage repair. In humans, four members of the FOXO transcription factors have been identified: FOXO1, FOXO3a, FOXO4 and FOXO6 [14,15]; they share a high degree of evolutionary ... See full document
8
A genome wide meta-analysis study for identification of common variation associated with breast cancer prognosis.
... [26] in R.2.14.0 environment to perform survival analysis using post-QC genome wide SNP ...of breast cancer and the date of death due to breast cancer or the date ... See full document
10
Monocarboxylate transporter 4 facilitates cell proliferation and migration and is associated with poor prognosis in oral squamous cell carcinoma patients.
... ways. In both HN4 and HN6 cells, depletion of integrin b4, induced by MCT4 silencing, blocked the phosphorylation of FAK- Tyr397, FAK-Tyr925, SRC, MEK, and ERK1/2 without affecting the total levels ... See full document
11
Association of MMP8 gene variation with breast cancer prognosis
... Breast Cancer Res 2008, 10(Suppl 2):P65 (doi: ...Background Cancer Research UK (2007) [1] stated that the most common cancer for women in the United Kingdom is breast ... See full document
49
mTOR pathway in BRAF mutated papillary thyroid carcinoma.
... which is coun- teracted by the phosphatase and tensin homolog ...status is connected to mTORC1 through AMP-activated protein kinase (AMPK), which is activated in response ... See full document
11
CITED2 and the modulation of the hypoxic response in cancer
... ability to hydroxylate HIF-1α, which prevents its interaction with VHL and proteasomal ...translocates and accumulates in the nucleus, and associates with the HIFβ subunit ... See full document
19
Rev. Bras. Hematol. Hemoter. vol.34 número5
... relevant to the diagnosis and treatment of Chronic myeloid leukemia ...strategies to search for evidence (Appendix 1) in the main scientiic electronic databases (Medline/PubMed, Embase, ... See full document
16
Arq. Gastroenterol. vol.52 número4
... patients with recurrence in each group were G/G genotype ...patients with microvascular invasion and poorly differentiated tumors presented G/G genotype ...present in most patients ... See full document
6
The differences in ultrasound and clinicopathological features between basal-like and normal-like subtypes of triple negative breast cancer.
... compared with other forms of breast cancer and that is associated with relatively high rates of recurrence, distant metastases and low overall survival rates ... See full document
13
Factors associated with oxidative stress in women with breast cancer
... Objective: To assess the association between physiolog- ical, physical, lifestyle and nutritional variables and oxidative stress biomarkers in women with breast ...diagnosed ... See full document
9
The Pro allele of the p53 codon 72 polymorphism is associated with decreased intratumoral expression of BAX and p21, and increased breast cancer risk.
... SNP is a biologically plausible candidate low penetrance genetic risk factor, and its association with breast cancer risk has been investigated by several ...studies. In some ... See full document
10
Rev. Saúde Pública vol.42 número2
... it is essential to provide accurate information focusing on disease prevention, such as breast cancer prevention, to both the target population and health professionals working ... See full document
8
PD-L1 expression is increased in a subset of basal type breast cancer cells.
... expression in basal cell lines could be confirmed in a larger ...for basal and non-basal breast cancer cell ...the basal cell lines was significantly greater ... See full document
10
Association between the STK15 F31I polymorphism and cancer susceptibility: a meta-analysis involving 43,626 subjects.
... relevant to the topic were identified from databases (PubMed, Embase, CBM and ...CNKI). With additional filters, 120 of these articles were excluded (26 for duplication of titles, 10 for not being ... See full document
13
The expression of TMPRSS4 and Erk1 correlates with metastasis and poor prognosis in Chinese patients with gastric cancer.
... proteases with a proteolytic domain, a transmembrane domain, a short cytoplasmic domain and a stem region of variable length that contains modular structural ...implicated in tumor development ... See full document
7
Impact of premature ovarian failure on mortality and morbidity among Chinese women.
... rate and follow-up rates were high, and follow-up surveys were conducted biennially to ascertain outcomes and changes in chronic disease ...able to adjust for a wide range of ... See full document
8
Association between 5p12 genomic markers and breast cancer susceptibility: evidence from 19 case-control studies.
... ed in statistical ...according to ethnicity, sample size. In the stratified analysis by ethnicity, significant associations were found in Asians and Caucasians for the two polymorphisms ... See full document
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