[PDF] Top 20 Oxygen mediates vascular smooth muscle relaxation in hypoxia.
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Oxygen mediates vascular smooth muscle relaxation in hypoxia.
... involved in several vital intracellular signalling cascades and physiological processes ...increase in basal sGC activity independently of other ligands, while also potentiating the responses to subsequent ... See full document
9
NOX4 mediates BMP4-induced upregulation of TRPC1 and 6 protein expressions in distal pulmonary arterial smooth muscle cells.
... that in PASMCs, BMP4 increased ROS generation, at least in part, is mediated by ...role in occurrence and development of CHPH, mainly in the following three aspects: 1) regulates proliferation ... See full document
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Reactive oxygen species and angiotensin II signaling in vascular cells - implications in cardiovascular disease
... II in vascular smooth muscle ...reactive oxygen species (ROS) modify the activity of tyrosine kinases, such as Src, Ras, JAK2, Pyk2, PI3K, and EGFR, as well as mitogen-activated protein ... See full document
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Effects of the postannealing atmosphere on the dielectric properties of (Ba, Sr)TiO3 capacitors: Evidence of an interfacial space charge layer
... Postannealing in an oxygen atmosphere increased the dielectric relaxation phenomenon, while a slighter dielectric relaxation phenomenon was observed when the capacitor was postannealed ... See full document
4
Mechanisms for suppressing NADPH oxidase in the vascular wall
... 1996). In neutrophils, PR-39 inhibits NADPH oxidase activity by binding to the Src homology 3 domain of the p47phox subunit, thereby blocking its interaction with the membrane bound p22phox (Shi et ...PR-39 ... See full document
8
Hypertensive effects of the iv administration of picomoles of ouabain
... release in the brain is very sensitive to sodium loading ...pg) in Dahl salt-sensitive rats (DSS) is as- sociated with activation of the renin-angiotensin-aldosterone system in the hypothalamus and ... See full document
7
Differential expression of miR-145 in children with Kawasaki disease.
... validated in independent patient ...implicated in KD pathogenesis [5].This miR is increased in the setting of heart failure in humans ...qRT-PCR in the independent cohort (Figure ... See full document
12
Arq. Bras. Cardiol. vol.87 número5
... ticlopidine in relation to the restenosis rate, both associated with ASA, in a multicenter study with 397 patients submitted to elective coronary stent placement procedures and followed for six ...months. ... See full document
5
Dual regulation of myocardin expression by tumor necrosis factor-α in vascular smooth muscle cells.
... increase in VSMC proliferation by ...increase in VSMC ...expression in cerebral VSMCs [14] and that NF-kB inhibits myocardin by physically interacting with myocardin ...that in our studies the ... See full document
13
Vascular endothelial dysfunction in β-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO.
... separately in the presence of liquid nitrogen, and the powder was homogenized in lysis buffer (pH 8) containing 20 mmoles/L Tris- HCl, 150 mmoles/L NaCl, 2 mmoles/L EDTA and ...milk in ... See full document
8
Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency.
... observed in the whole aortas of MGP -/- mice, it was possible that individual cells types within the vasculature such as VSMCs might exhibit in- creased BMP signaling in the absence of MGP [23, 24, ... See full document
21
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease
... one in terms of dwell time, then it would necessarily fol- low that the permeation rates of solutes seek- ing transit from cell to cell would be quite dependent on the nature of the subconducting ...time in ... See full document
8
Arq. Bras. Cardiol. vol.98 número4 en v98n4a11
... MicroRNAs in diagnostic testing and prognosis of heart failure Because many miRNAs are tissue specific, most clinical studies have been based on the measurement of expression levels of miRNAs in origin ... See full document
8
A DNA enzyme targeting Egr-1 inhibits rat vascular smooth muscle cell proliferation by down-regulation of cyclin D1 and TGF-β1
... The catalytic DNA, ED5, and scrambled control DNA enzyme, ED5SCR, were synthesized by Takara (China). The sequences were as follows: ED5 5’-CCGCTGCCAGG CTAGCTACAACGACCCGGACGT-3’; ED5SCR 5’-GCC ... See full document
9
Einstein (São Paulo) vol.11 número3 en a21v11n3
... role in progression of vascular ...discuss in further detail below, PMOs can promote vascular calcification directly (RANKL and BMPs) or, ultimately, serve as constitutive biomarkers of ... See full document
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Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina Orientador: Maria Alexandra de Oliveira Silva Braga Pedreira de Brito, Professora Auxiliar, Faculdade de Farmácia, Universidade de Lisboa Co-orientador: Dora Maria Tuna de Oli
... expressed in the brain (Aurrand-Lions et al., 2001) that is involved in cell-to-cell adhesion and takes part in the formation of TJs as an integral membrane protein together with occludin and ... See full document
85
Phenotypic modulation of primary vascular smooth muscle cells by short-term culture on micropatterned substrate.
... an in vivo-like elongated morphology in the differentiated state, we created a PDMS substrate with parallel microgrooves that mimic the cellular ...m in width, 5 m m in height) so several ... See full document
10
Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling
... °C in DMEM (Gibco, Bleiswijk, the ...resuspended in growth medium (DMEM with 10% FCS, Gibco, 100 U/ ml penicillin and 100 mg/ml streptomycin, Gibco) and transferred to culture ...maintained in ... See full document
11
Tetraspanin CD9 regulates cell contraction and actin arrangement via RhoA in human vascular smooth muscle cells.
... Smooth muscle cell basal media (SmBM), fetal bovine serum (FBS), recombinant human epidermal growth factor (rhEGF), recombinant human fibroblast growth factor (rhFGF), recombi- nant human insulin, and ... See full document
9
Cellular signaling with nitric oxide and cyclic GMP
... one in the cytosolic compartment and one in the membranous compartment or ...or in combination and recharac- terize the crude soluble and particulate guanylyl ...that in- creased cyclic GMP ... See full document
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