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[PDF] Top 20 Phenotypic changes induced by IL-15 in human CD8+ T cells in vitro

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Phenotypic changes induced by IL-15 in human CD8+ T cells in vitro

Phenotypic changes induced by IL-15 in human CD8+ T cells in vitro

... or in combination with other regimens is currently being investigated in phase I/II clinical trials for the treatment of various types of cancer ...with IL-15 is associated with malignant ... See full document

63

Interleukin-15 augments oxidative metabolism and fungicidal activity of human monocytes against Paracoccidioides brasiliensis

Interleukin-15 augments oxidative metabolism and fungicidal activity of human monocytes against Paracoccidioides brasiliensis

... that in vitro treatment with IL-15 significantly increases monocyte fungicidal activity against Pb18, mainly at a concentration of 50 ng/ mL, showing that IL-15 potentiates ... See full document

7

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

... this, human peripheral blood samples were irradiated in vitro with different doses and P-gp activity was analyzed for CD4 and CD8 T lymphocytes through rhodamine123-efflux assay ... See full document

6

Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway.

Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway.

... alone in RCC is not sufficient to reestablish the cc chain-dependent IL-15 signaling (phosphorylation of STAT5), which is restored only after co- transfection of both ...existence in RCC of a ... See full document

14

Human CD8+ T Cells in Asthma: Possible Pathways and Roles for NK-Like Subtypes

Human CD8+ T Cells in Asthma: Possible Pathways and Roles for NK-Like Subtypes

... produced by human T cells, as shown in a study in which signaling through the TCR induced amphiregulin expression by most or all human T cell subsets ... See full document

7

Perforin and Gamma Interferon Expression Are Required for CD4(+) and CD8(+) T-Cell-Dependent Protective Immunity against a Human Parasite, Trypanosoma cruzi, Elicited by Heterologous Plasmid DNA Prime-Recombinant Adenovirus 5 Boost Vaccination

Perforin and Gamma Interferon Expression Are Required for CD4(+) and CD8(+) T-Cell-Dependent Protective Immunity against a Human Parasite, Trypanosoma cruzi, Elicited by Heterologous Plasmid DNA Prime-Recombinant Adenovirus 5 Boost Vaccination

... of T-cell responses is critical to avoiding autoimmu- nity and immune-pathological damages ...or in vitro) reported by distinct groups, including ours (8, 15, 32, ...experimental ... See full document

13

Expansion of NK cells and reduction of NKG2D expression in chronic lymphocytic leukemia. Correlation with progressive disease.

Expansion of NK cells and reduction of NKG2D expression in chronic lymphocytic leukemia. Correlation with progressive disease.

... and CD8 cell cytotoxic activity. PBMCs from healthy donors stimulated with IL-2 (5 ng/ ml), IL-15 (25 ng/ml), IL-21 (20 ng/ml) for 48 hours or lenalidomide (1 m M) for 7 days were ... See full document

9

Changes in liver cell DNA methylation status in diabetic mice affect its FT-IR characteristics.

Changes in liver cell DNA methylation status in diabetic mice affect its FT-IR characteristics.

... obtained by caudal puncture and subjected to weekly analyses by an automatic Accu-Check Active Performa glucose meter (Roche Diagnostic do Brasil, Jaguare´, Brazil) up to 24 h before they were ...matched ... See full document

7

Einstein (São Paulo)  vol.9 número2

Einstein (São Paulo) vol.9 número2

... The major complications after bone marrow transplant are related to opportunistic infections or to graft-versus-host disease. Today, there is a wealth of information associated with bone marrow transplantation and new ... See full document

3

Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells.

Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells.

... derived by transducing skin cells with a modified version of our ‘‘Hit and Run’’ lentiviral vector [19] carrying Oct4, Sox2, Klf4 and c-Myc cDNAs driven by the EF-1a ...factors by infection ... See full document

10

T cells are not required for vaccine-induced immunity against Leishmania amazonensis in IL-1223P40

T cells are not required for vaccine-induced immunity against Leishmania amazonensis in IL-1223P40

... seen in culture supernatants of lymph nodes and spleens of IL-12/23p40 / mice were ab- rogated when CD8 þ T cells were ...for T cell- mediated delayed-type immune response, ... See full document

11

Phosphatidylinositol 3-Kinase γ is required for the development of experimental cerebral malaria.

Phosphatidylinositol 3-Kinase γ is required for the development of experimental cerebral malaria.

... pathogenic CD8+ T cells in the brain vasculature after PbA infection is PKC-θ-dependent, but PKC-θ deficiency does not protect against PbA-induced lung ...disease. In the current ... See full document

13

Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection.

Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection.

... reduced in TB patients, highly suggestive of a restricted functional profile of Mtb- specific CD8 T-cells during active ...of CD8 T-cells at a single cell level in ... See full document

10

Assessment Of NPK In Human Male And Female Urine For Its Fertilising Potential In Agriculture

Assessment Of NPK In Human Male And Female Urine For Its Fertilising Potential In Agriculture

... reduced by about 60% irrespective of the type of treatment ...nutrients in normal sewage; 80% of N, 55% of P, and 60% of K in just ...nitrogens in urine among primates such as man, mangabeys, ... See full document

9

Tolerance to the neuron-specific paraneoplastic HuD antigen.

Tolerance to the neuron-specific paraneoplastic HuD antigen.

... either by regulatory T cells or through induction of anergy of CD8+ T cells in the periphery, requires a means for antigen to be captured and presented to antigen ... See full document

8

J. Bras. Nefrol.  vol.38 número4

J. Bras. Nefrol. vol.38 número4

... 4. Hemmett J, Er L, Chiu HH, Cheung C, Djurdjev O, Levin A. Time to revisit the problem of CIN? The low incidence of acu- te kidney injury with and without contrast in hospitalized pa- tients: an observational ... See full document

2

Oral Administration of p-Hydroxycinnamic Acid Attenuates Atopic Dermatitis by Downregulating Th1 and Th2 Cytokine Production and Keratinocyte Activation.

Oral Administration of p-Hydroxycinnamic Acid Attenuates Atopic Dermatitis by Downregulating Th1 and Th2 Cytokine Production and Keratinocyte Activation.

... captured by Langerhans cells (LC) activated by kera- tinocytes which produce a set of proinflammatory cytokines in the inflamed ...surface in the context of major histocompatibil- ity ... See full document

18

Avaliação do potencial profilático de células dendríticas transfectadas com RNA fúngico em modelo experimental de esporotricose sistêmica

Avaliação do potencial profilático de células dendríticas transfectadas com RNA fúngico em modelo experimental de esporotricose sistêmica

... involved in the prevention and control of sporotrichosis are not fully ...role in the protection of the host against this fungus (Scott and Muchmore 1989; Carlos, Sgarbi et ...primary T cell-mediated ... See full document

138

Changes in protein interaction networks between normal and cancer conditions: Total chaos or ordered disorder?

Changes in protein interaction networks between normal and cancer conditions: Total chaos or ordered disorder?

... proteins in five tissues in case of cancer conditions were ...code in JAVA programming language for identifying upregulated signaling proteins (the normal expression of all proteins were subtracted ... See full document

14

Functional and phenotypic characterization of CD8+CD28+ and CD28- T cells in atopic individuals sensitized to Dermatophagoides pteronyssinus

Functional and phenotypic characterization of CD8+CD28+ and CD28- T cells in atopic individuals sensitized to Dermatophagoides pteronyssinus

... Responder cells were cultured at a concentration of 0.5 × 106 cells/ml for 6 days in RMPI 1640 com- plete medium [RPMI 1640, 2 mM L-glutamine, 1 % antibiotic/antimicotic (Sigma-Aldrich, St Louis, MO, ... See full document

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