[PDF] Top 20 Photodynamic DNA damage induced by phycocyanin and its repair in Saccharomyces cerevisiae
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Photodynamic DNA damage induced by phycocyanin and its repair in Saccharomyces cerevisiae
... (15,16). Its structure is based on an open- chain tetrapyrrolic chromophore covalently bound to an apoprotein, which possesses two chromophores attached to the alpha sub- unit and one to the beta subunit ... See full document
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Measuring DNA lesions induced by chemotherapeutic agents – DNA repair and DNA Damage
... C and D, shows the response of cell lines when exposed for 48h to ...reduction in cell viability when the exposed concentration rises from 100nM to 500nM of DOX, ranging from a percentages of 70% to 30% ... See full document
66
Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer
... DSB repair requires a homologous DNA se- quence provided by the sister homologous chromatid to re- store a DSB ...S and G2 cell-cycle phases, where this sister chromatid is available as a ... See full document
13
Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells
... on DNA mole- cules is ...through its activation of AMPK, thereby in- creasing nitric oxide synthase (Zhou et ...activation by way of ...effects by playing a role in the gene ... See full document
6
Evaluation of prevention of DNA damage and induction of DNA repair by natural compounds
... to Saccharomyces cerevisiae, because this is a fast growing organism and its cultivation is cheap and easy to ...Evaluation and Authorisation of Chemicals), it is recommended ... See full document
39
Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast Cancers.
... codon and leads to a shortened PALB2 protein, which is devoid of the C-terminal domain that appears to be nec- essary for BRCA2/PALB2 complex formation [51] and homologous recombination repair ... See full document
14
Antimicrobial-induced DNA damage and genomic instability in microbial pathogens.
... implicated in antimicrobial-induced mutations. In bacteria, the RpoS sigma factor is a central regulator of the general stress re- sponse, which is activated in response to stress ... See full document
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Caracterização da resposta SOS em Leptospira interrogans sorovar Copenhageni
... genus in an ancient group of bacteria, the ...distribution and of public health importance in developed tropical ...leptospirosis in Brazil. In this work, we used a great variety of ... See full document
116
Ndd1 turnover by SCF(Grr1) is inhibited by the DNA damage checkpoint in Saccharomyces cerevisiae.
... levels in damaged-arrested cells ...ated by Cdk1 activity, we examined whether Ndd1 stabilization in response to DNA damage required the kinase Swe1 (Fig 4A, quantified in Fig ... See full document
16
Relationships between chromatin remodeling and DNA damage repair induced by 8-methoxypsoralen and UVA in yeast Saccharomyces cerevisiae
... Mutations in the yeast RSC chromatin remodeling complex (Table 1) cause hypersensitivity to DNA break- inducing agents (van Attikum and Gasser, ...homologs in other eukaryotes and acts ... See full document
8
Actividade moduladora de extracto de Ginkgo biloba no ciclo celular de Saccharomyces cerevisiae e capacidade de reparação de danos de DNA em células sob stresse replicativo
... cytotoxic DNA lesions, [13] mainly, the wide class of single-strand lesions that destabilize the double helix, including damages induced by ultraviolet light and DNA intrastrand ... See full document
46
Initiation of genome instability and preneoplastic processes through loss of Fhit expression.
... deleterious DNA lesions as they are difficult to repair correctly and often lead to complex genomic alterations, including large deletions, duplications, and translocations ...during ... See full document
16
Trypanosome Prereplication Machinery Contains a Single Functional Orc1/Cdc6 Protein, Which Is Typical of Archaea
... TcOrc1/Cdc6 and TbOrc1/Cdc6 are located in the nucleus during the entire cell cycle and since it has been ob- served sometimes in mammalian cells that Orc1 is released from the chromatin ... See full document
12
Tese PhD Rita Ferreira
... As(V), and washed three times with phosphate-buffered saline (PBS) to remove arsenic ...resuspended in fresh media supplemented with cycloheximide (CHX) to a final concentration of ...mg/ml, and ... See full document
165
Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination.
... frequent in nature and is a hallmark of cancer cells, but little is known about the strategy of DNA repair in polyploid ...studied DNA repair in the polyploid ... See full document
12
Braz. J. Pharm. Sci. vol.45 número4
... Oxidative DNA damage to the hepatocytes was determined by the Comet test (single cell gel assay) ac- cording to Rojas and coworkers ...filters and a barrier of 515-560 nm and 590 ... See full document
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Rev. bras. ter. intensiva vol.23 número1 en a17v23n1
... stay in the internal medicine ward, while presenting improved WBC and cultures negative for germs, the patient experienced tachypnea and respiratory ...suspended, and new antibiotics the rapy ... See full document
4
Assessment of the DNA Damage in Human Sperm and Lymphocytes Exposed to the Carcinogen Food Contaminant Furan with Comet Assay
... The DNA is the critical target for lethal, carcinogenic, teratogenic and mutagenic effects of ionizing radiation and other environmental ...fast and sensitive methods for monitoring DNA ... See full document
8
Polyhydroxyfullerene binds cadmium ions and alleviates metal-induced oxidative stress in saccharomyces cerevisiae
... ullerene and functionalized fullerenes are carbon-based nano- particles with enormous implications for nanotechnology due to their applications in several fields, such as biomedical diagnos- tics and ... See full document
8
Effect of pH, dextrose and yeast extract on cadmium toxicity on Saccharomyces cerevisiae PE-2
... The pollution of the environment with toxic heavy metals has been increasing throughout the world with industrial progress. It is important to establish an efficient and low-cost method for the removal of metal ... See full document
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