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[PDF] Top 20 DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions

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DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions

DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions

... Specific DNA repair pathways from Trypanosoma cruzi are believed to protect genomic DNA and kine- toplast DNA (kDNA) from ...operate in order to ... See full document

10

BQ1 - CLONING AND CHARACTERIZATION OF DNA POLYMERASE BETA FROM TRYPANOSOMA CRUZI

BQ1 - CLONING AND CHARACTERIZATION OF DNA POLYMERASE BETA FROM TRYPANOSOMA CRUZI

... Trypanosoma cruzi, the ethiologic agent of Chagas disease, is transmitted through triatomine insects vectors during the blood-meal on vertebrate ...ingest in a single meal about 10 mM ... See full document

17

The Trypanosoma cruzi nucleic acid binding protein Tc38 presents changes in the intramitochondrial distribution during the cell cycle

The Trypanosoma cruzi nucleic acid binding protein Tc38 presents changes in the intramitochondrial distribution during the cell cycle

... Trypanosoma cruzi the protozoan responsible for Chagas disease belongs to a group of organisms that branched very early in eukaryotic ...quence of its evolutionary distance from ... See full document

11

A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation.

A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation.

... identified in the POLB gene, but little is known about their cellular and biochemical ...impact. DNA Polymerase b (Pol b), encoded by the POLB gene, is the main gap-filling ... See full document

10

Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions

Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions

... versatile repair pathways in mammalian cells. In NER, there are two subpathways that differ only in the recogni- tion of DNA damage, ...coupled repair (TCR), which ... See full document

11

BI-2 PROSPECTIVE EVALUATION OF POLYMERASE CHAIN REACTION OF TRYPANOSOMA CRUZI KINETOPLAST MINICIRCLE DNA AND NUCLEAR SATELITE DNA FOR DIAG-

BI-2 PROSPECTIVE EVALUATION OF POLYMERASE CHAIN REACTION OF TRYPANOSOMA CRUZI KINETOPLAST MINICIRCLE DNA AND NUCLEAR SATELITE DNA FOR DIAG-

... study of Chagas’ disease. Three forms of the disease have been reproduced in dogs: acute symptomatic, indeterminate and chronic ...form of the disease has not yet been detected. The ... See full document

61

Relationship between BiologicaI Behaviour and Randomly Amplified Polymorphic DNA Profiles of Trypanosoma cruzi Strains

Relationship between BiologicaI Behaviour and Randomly Amplified Polymorphic DNA Profiles of Trypanosoma cruzi Strains

... biochemical and genetic characteristics of Trypanosoma cruzi isolates with the clinical variability of Chagas dis- ease have been reported (Gonzalez et ...Studies of natural ... See full document

6

Estabilidade de microssatélite do DNA nuclear e mitocondrial de Trypanosoma cruzi

Estabilidade de microssatélite do DNA nuclear e mitocondrial de Trypanosoma cruzi

... no DNA, a 7,8-dihidro-8-oxoguanina (ou apenas 8oxoG) representa a lesão mais abundante (MAZUREK et ...no DNA envolve a reação do ROS com o DNA, o radical hidroxila inicialmente reage com a base ... See full document

80

MAYKON TAVARES DE OLIVEIRA

MAYKON TAVARES DE OLIVEIRA

... T. cruzi da escolha de tais marcadores ou alvos ainda não ser um consenso e de que, geralmente, a resolução segura dos isolados do parasito em seus seis subgrupos requer a combinação de diferentes metodologias, ... See full document

111

Sunlight damage to cellular DNA: Focus on oxidatively generated lesions

Sunlight damage to cellular DNA: Focus on oxidatively generated lesions

... non-helix-distorting lesions by removing and repairing damage sustained by deamination, alkylation or oxidation processes, including those induced by ...tion and excision by a DNA glycosylase ... See full document

15

Rev. Soc. Bras. Med. Trop.  vol.31 número3

Rev. Soc. Bras. Med. Trop. vol.31 número3

... O nível de sensibilidade detectada para a PCR foi de 10fg de DNA do T. c ruzi revelado com sais de prata e 0,1fg após hibridização em Slot-Blot com sonda específica, correspondendo a um parasita intacto ou 0,01% ... See full document

2

DNA polimerase beta: uma proteína envolvida na replicação e reparo do DNA mitocondrial emTrypanosoma cruzi

DNA polimerase beta: uma proteína envolvida na replicação e reparo do DNA mitocondrial emTrypanosoma cruzi

... primer in vitro, sugerindo participação da polimerase em processos de síntese de ...(Nakajima-Shimada and Aoki ...T. cruzi e atribuiu esta atividade à DNA ...do DNA (Copeland et ... See full document

138

OPTIMIZATION OF RANDOM AMPLIFIED POLYMORPHIC DNA TECHNIQUES FOR USE IN GENETIC STUDIES OF CUBAN TRIATOMINAE

OPTIMIZATION OF RANDOM AMPLIFIED POLYMORPHIC DNA TECHNIQUES FOR USE IN GENETIC STUDIES OF CUBAN TRIATOMINAE

... products in PCR to generate RAPD. Varying concentrations of MgCl 2 ...mM) in the PCR mixture resulted in both quantitative differences in RAPD derived DNA and qualitative ... See full document

6

Association between the c.910A.G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population

Association between the c.910A.G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population

... EC is a common and polygenic malignant cancer caused by complex interactions between genetic and environmental ...It is a global health problem. A large number of studies have been ... See full document

5

Comparative Analysis by Polymerase Chain Reaction Amplified Minicircles of Kinetoplast DNA of a Stable Strain of Trypanosoma cruzi from São Felipe, Bahia, its Clones and Subclones: Possibility of Predominance of a Principal Clone in this Area

Comparative Analysis by Polymerase Chain Reaction Amplified Minicircles of Kinetoplast DNA of a Stable Strain of Trypanosoma cruzi from São Felipe, Bahia, its Clones and Subclones: Possibility of Predominance of a Principal Clone in this Area

... extracted from the 21 SF strain, its clones and subclones according to Gonçalves et ...loaded in a 2% agarose gel elec- trophoresis in TAE buffer ...EDTA) and UV light examined after ... See full document

8

Estudos de reparo de DNA por excisão de nucleotídeos em lesões oxidativas em células...

Estudos de reparo de DNA por excisão de nucleotídeos em lesões oxidativas em células...

... no DNA surgiram a partir das investigações de danos gerados por radiação ultravioleta (UV), devido à facilidade em reproduzir e medir esse tipo de sistema (CALLEGARI et ...do DNA são capazes de absorver ... See full document

41

Thermostable DNA polymerase from a viral metagenome is a potent RT-PCR enzyme.

Thermostable DNA polymerase from a viral metagenome is a potent RT-PCR enzyme.

... shown in Figure 6, it was noticeably less consistent with less abundant ...inconsistency is not fully understood and is under ...enzyme is sensitive to high abundances of ... See full document

13

REPOSITORIO INSTITUCIONAL DA UFOP: Experimental Trypanosoma cruzi biclonal infection in Triatoma infestans : detection of distinct clonal genotypes using kinetoplast DNA probes.

REPOSITORIO INSTITUCIONAL DA UFOP: Experimental Trypanosoma cruzi biclonal infection in Triatoma infestans : detection of distinct clonal genotypes using kinetoplast DNA probes.

... mixtures of T. cruzi clonal genotypes are very frequent ...relevance of these mixtures could be high (phenomena of clonal cooperation and clonal ...detection of mixtures, ... See full document

6

Characterization of family IV UDG from Aeropyrum pernix and its application in hot-start PCR by family B DNA polymerase.

Characterization of family IV UDG from Aeropyrum pernix and its application in hot-start PCR by family B DNA polymerase.

... (UDG) from Aeropyrum pernix ...range and pH value for dU removal by ApeUDG were 55–65uC and pH ...removal of dU was inhibited by the divalent ions of Zn, Cu, Co, Ni, and Mn, as ... See full document

10

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair.

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair.

... (DSB) in DNA are a highly deleterious type of genetic damage, potentially causing genomic rearrangements or cell death if ...mechanism of DSB repair in mammals is thought ... See full document

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