[PDF] Top 20 Polymorphisms in XPD gene could predict clinical outcome of platinum-based chemotherapy for non-small cell lung cancer patients: a meta-analysis of 24 studies.

... Although platinum-based doublet chemotherapy is currently considered as the standard care for first-line treatment of advanced NSCLC, a large proportion of patients display ... See full document

... variants in the telo- merase reverse transcriptase (TERT) gene associated with lung cancer risk ...subunit of the telomerase ribonucleoprotein complex, which catalyzes the addition ... See full document

... development of new diagnostic, prognostic and predictive markers could significantly enhance its early detection ...Tissue Cancer (CASTLE) network are particularly awaited. In fact, this study ... See full document

... out of the included trials [19,22,26–32] were evaluating platinum-based chemotherapy plus BSC compared with BSC alone, 2 [17–18] were assessing gemcitabine or vinorelbine therapy plus BSC ... See full document

... O gene KLK3 ou PSA codifica uma protease do tipo serina, produzida predominantemente pela próstata, mais especificamente pelas células secretoras ...Institute of Science, ... See full document

... difference in the rate of FGFR1 amplification between squamous cell and adenocarcinomas as previously reported ...differences in technologies and cutpoint definitions, variability in ... See full document

... al. In vitro evaluation of the new anticancer agents KT6149, MX-2, SM5887, menogaril, and liblomycin using cisplatin- or adriamycin-resistant human cancer cell ... See full document

... SCLC patients and found to be only useful in patients with an increased pre-treatment level ...levels of lactate dehydrogenase and chromogranin A did not correlate with treatment response ... See full document

... because of insufficient data for meta-analysis. Non-English language papers were not included in the ...duplication of patient data, we carefully noted the author names and the ... See full document

... differences in non- small cell lung cancer ...An analysis of 4618 patients diagnosed between 1997 and ... See full document

... analyzed in respect to the five-year survival, there were three different groups: N0 and N1, for which the prognoses were similar; N2; and ...future studies are needed in order to achieve a better ... See full document

... edition of the TNM classification system for lung cancer emphasizes the prognostic relevance of the tumor size much more than did the previous ...changes in the node descriptor, the ... See full document

... Recently, studies in the ield of epidermal growth factor (EGF) +61A/G polymorphisms have shown their relevance in relation to cancer ...role of EGF+61 genotypes has been ... See full document

... for patients with non- small cell lung cancer after the failure of platinum- containing ...aim of this study was to explore the efficacy and safety of ... See full document

... human lung and lung cancer tissues or A549 cells using Trizol reagent (Invitrogen, ...given in the Table ...housekeeping gene glyceraldehyde-3-phos- phate dehydrogenase GAPDH was used ... See full document

... quality of diagnostic ...significance of variables for OS, PFS, and the log-rank test was utilized to examine the significant differences of survival distributions between differ- ent levels ... See full document

... cycles of Cisplatin and etoposide (30 mg/m 2 ). On completion of six cycles there was dramatic radiological (Figure 1c) and clinical response with karnofsky of 90 and ECOG of ... See full document

... Scintigrafija skeleta je standardna metoda nuklearne medicine koja se koristi za otkrivanje metastaza u kostima bolesnika obolelih od maligne bolesti. Sekundarni depoziti u kostima su u našoj grupi ispitanika ... See full document

... The object of corrosion studies were as-cast samples of M g-Li alloys of 30 x 20 x 10 mm dimensions designated as: - alloy no. 1 containing 3,54% Li (monophase  hcp alloy), - alloy no. 2 ... See full document

... 50% of patients with newly diagnosed non-small cell lung cancer (NSCLC) are over 70 years of age at ...these patients are underrepresented in ... See full document