[PDF] Top 20 Post-transcriptional regulation in the developing embryo
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Post-transcriptional regulation in the developing embryo
... done in Xenopus, zebrafish, chick and mouse have shown that the FGF signalling pathway is required for the formation of the mesodermal germ layer during the gastrula phase (Slack et ... See full document
218
miRNA regulation of gene expression: a predictive bioinformatics analysis in the postnatally developing monkey hippocampus.
... of the expression of these genes expressed in different cell ...considered the involvement of miRNAs (small RNA molecules acting as post-transcriptional regulatory elements), which have ... See full document
11
RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways.
... at the University of California Los Angeles, in accordance with protocols approved by the University of California Los Angeles Institutional Review Board, as previously described ...after the ... See full document
14
Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.
... for the zebrafish kif7 (set 3) gene were purchased from Sigma (see accompanying data ...by in vitro transcription and a range of doses was injected into one-cell stage zebrafish ...of the amplicon ... See full document
15
Patterning in time and space: HoxB cluster gene expression in the developing chick embryo
... The developing embryo is a paradigmatic model to study molecular mechanisms of time control in ...players in the speci fication of tissue identity during embryo development ... See full document
11
The loss of miR-26a-mediated post-transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival.
... during the cell cycle. These cyclins are of particular interest in pancreatic ...upregulates the expression of cyclin D2 and cyclin E2 mRNA in ...miR-26a in pancreatic cancer. On ... See full document
10
Cdx, Wnt signalling and anterior Hox genes in the regulation of the posterior growth zone in mouse embryo
... of the placenta, a phenotype similar to that of Cdx2/4 ...decrease in Wnt signaling below the needed ...monitoring the activity of the canonical Wnt signaling via qPCR of the Wnt ... See full document
58
The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.
... effects. Transcriptional dysregulation has been proposed to be a central component of HD pathogene- sis ...of the stages of RNA processing, translation, protein post-translational modification and ... See full document
23
Regulation of DII4 expression in cells committing to differentiation in the V2 domain of the developing spinal cord
... but the molecular mechanisms underlying such cell diversity remain poorly ...of the mechanisms that has been involved in the generation of neuronal diversity is the cell-cell signalling ... See full document
55
Regulatory elements involved in the post-transcriptional control of stage-specific gene expression in Trypanosoma cruzi - A Review
... leave the insect vector and infect mammalian cells. The heat-shock response may be part of the differen- tiation process and may be a protection mechanism for parasite survival (McNicoll et ...are ... See full document
10
Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse.
... of the cardiovascular system are the most common type of birth defect in humans, frequently affecting the formation of valves and ...from the atrio-ventricular canal (AVC) and outflow ... See full document
14
p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis?
... p14ARF in response to IPTG treatment (Figure 1A). To determine the effects of p14ARF on cell proliferation we examined 1) newly synthesised DNA post-p14ARF using EDU chemistry and 2) cell cycle ... See full document
16
Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle.
... hours post treatment were lyzed in saponin ...PBS. The isolated parasites were resuspended directly in SDS sample buffer, incubated at 100 uC for 10 min and centrifuged at 16,000g for 10 ... See full document
13
Combinatorial action of miRNAs regulates transcriptional and post-transcriptional gene silencing following in vivo PNS injury.
... Induces Transcriptional Gene Silencing of Egr2 So far we have demonstrated that miRNAs employ a combinatorial mechanism for regulation of translation following PNS ...protein the expression of which ... See full document
14
Transcriptional and post-transcriptional control of eEF1A2 expression during myoblast diffrerentiation
... development, the switch of the expression from iso- form A1 to the isoform A2 of eukaryotic translation elongation factor (eEF1A) is observed in neuronal and muscle ...tissues. The ... See full document
5
TRANSCRIPTIONAL REGULATION OF THE MANNOSYLTRANSFERASE-ENCODING GENE PIGM IN INHERITED GLYCOSYLPHOSPHATIDYLINOSITOL (GPI) DEFICIENCY
... marrow. In adult life, erythroid precursors are mainly produced in the bone marrow and once they mature, they expel their nucleus and enter the ...bloodstream. The growth of burst ... See full document
186
Engineering transcriptional regulation to control Pdu microcompartment formation.
... positive transcriptional regulator EutR that is transcribed at the 3 9 end of the Eut operonpolycistron, instead of divergently transcribed on another cistron as is ...compartments in response ... See full document
14
Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms
... and in an attempt to determine possible PTM’s in STEAP1 protein, in silico analysis was carried ...occur in STEAP1 protein, namely N-glycosylation, glycation, phosphorylation and ...between ... See full document
10
POST-TRANSCRIPTIONAL REGULATION OF HFE GENE EXPRESSION
... that the expression of approximately 10% of the human transcriptome is regulated by NMD [Mendell et ...feature in common with their pathological counterparts: they possess a translation termination ... See full document
160
Post-translational regulation of Oct4 transcriptional activity.
... to the octamer half-site in the MORE configuration ...of the octamer motif, and presence of DNA motifs for additional transcription factors, Oct4 can form heterodimers with multiple partners ... See full document
9
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