[PDF] Top 20 Post-translational regulation of Oct4 transcriptional activity.
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Post-translational regulation of Oct4 transcriptional activity.
... enhance Oct4 protein levels; this enhancement was accompanied by activation of the p38 MAP kinase pathway (Figure 4A), as measured by western ...levels of Oct4 protein, P19 cells were treated ... See full document
9
Combinatorial action of miRNAs regulates transcriptional and post-transcriptional gene silencing following in vivo PNS injury.
... Induces Transcriptional Gene Silencing of Egr2 So far we have demonstrated that miRNAs employ a combinatorial mechanism for regulation of translation following PNS ...expression of ... See full document
14
Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms
... analysis of human STEAP1 and STEAP1B ...regions of coding exons depending on transcript encoded by STEAP1B ...Alignment of amino acids sequences of STEAP1 and putative STEAP1B ...Prediction ... See full document
10
Asymmetric post-translational modifications regulate the intracellular distribution of unstimulated STAT3 dimers
... its activity as well. Dysregulation of STAT3 activation initiates, contributes and sustains a variety of human diseases, including ...aim of this project was to study specific residues/domains ... See full document
58
Tese PhD Rita Ferreira
... group of ubiquitin-like proteins, such as SUMO that is also conjugated to the lysine residues of targeted substrates by an isopeptidic bond similar to that observed for the ubiquitin system ...aspects ... See full document
165
The loss of miR-26a-mediated post-transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival.
... antibodies of cyclin D2 (1:300 dilution; Millipore), cyclin E2 (1:300 dilution; Millipore), and proliferating cell nuclear antigen (PCNA) (1:300 dilution; Dako), overnight at 4 uC, with normal IgG as a negative ... See full document
10
In silico analysis of the endogenous time-keeping mechanism in citrus
... Post-transcriptional regulation is involved in several processes of circadian timing in ...mechanism of the mammalian circa- dian clock (Sugano et ...robustness of LHY ... See full document
23
Reverse-engineering post-transcriptional regulation of gap genes in Drosophila melanogaster.
... embryo of the vinegar fly Drosophila ...importance of post-transcriptional regulation in animal ...studies of pattern formation focus on differential transcriptional ... See full document
16
p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis?
... knockdown of cyclin D1, p53 and p21, that p21was necessary for the stability of cyclin D1 protein, independent of ...Suppression of p21, by downregulating p21 or p53, restored the mitogenic ... See full document
16
Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.
... region of interest, which are in the concentrated region of mutations found in Noonan and LEOPARD syndrome samples, follow the same pat- tern and exhibit no relative change until after 24 hours of ... See full document
14
ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... the post- transcriptional regulation of gene expression ...promoters of mRNA degradation; however, more recent evidence indicates a role in translational control as ...range ... See full document
12
Concentration and length dependence of DNA looping in transcriptional regulation.
... One of the puzzles that has so far been unresolved concerning DNA mechanics at short scales is whether in vivo and in vitro experiments tell a different ...repression of a given gene is measured as a ... See full document
17
The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cells.
... expression of many thousands of genes in appropriate spatial and temporal ...modification of the core histones (H3, H4, H2A, and H2B) that comprise nucleosomes, which are the fundamental units ... See full document
12
Computational characterization of modes of transcriptional regulation of nuclear receptor genes.
... long-range regulation of nuclear receptor family and their known ...counts of highly conserved non-coding ...evidence of long-range mechanism of transcription regulation with ... See full document
14
Novel transcriptional regulation mechanisms associated with Parkinson’s disease pathogenesis: from biological activity towards therapy
... control of the microtubule cytoskeleton by interaction with a kinesin motor molecule ...synaptic activity, mitogen activated protein kinase shuttles along axons toward the nucleus and the repair of ... See full document
68
Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer.
... predictive of poor outcome, and in cancer cells KIF14 can modulate metastatic behavior by maintaining appropriate levels of cell adhesion and migration proteins at the cell ...KIF14’s regulation in ... See full document
13
Análise diferencial da expressão gênica e proteica no corpo lúteo de bovinos submetidos...
... Transcriptional regulation of vascular endothelial growth factor gene expression in ovarian bovine granulosa cells.. Troglitazone inhibits progesterone production in porcine granulosa [r] ... See full document
177
The development of an open-access database for human transcriptional regulation interactions
... The HTRIdb offers several mechanisms of data query and extraction, such as download in spreadsheet or text format and the visualization of TF-TG interactions. There is an update mechanism that allows ... See full document
1
Engineering transcriptional regulation to control Pdu microcompartment formation.
... activation of the transcriptional reporter correlates with the formation of ...acids of the MCP-encapsulated enzyme PduP are fused to GFP to create an MCP-encapsulated fluorescent reporter ... See full document
14
Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.
... domain of MscL was found to be a hot mutational spot in a random mutagenesis study where many mutations, almost all to more hydrophilic residues, led to more sensitive or GOF channels ...hydrophilicity of ... See full document
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