[PDF] Top 20 Predicting protein phenotypes based on protein-protein interaction network.
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Predicting protein phenotypes based on protein-protein interaction network.
... common phenotypes. For example, the interactions of seed protein YBR039W with the other seed proteins are listed in Table ...that protein YBR039W and its neighbors YBL099W, YDL004W, YDR298C, YLR295C, ... See full document
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Predicting and validating protein interactions using network structure.
... stated interaction, with the aim to identify potentially false ...(4,355 protein pairs); 49 of which are found in DIP ...the interaction between ‘‘Protein TEM1’’ (TEM1) and ... See full document
11
Predicting Pharmacodynamic Drug-Drug Interactions through Signaling Propagation Interference on Protein-Protein Interaction Networks.
... PPI network [19, ...PPI network. However, previous methods for predicting PD DDIs have only the close ...drugs on the PPI network ...are on the PPI ...for predicting PD ... See full document
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Context-specific protein network miner--an online system for exploring context-specific protein interaction networks from the literature.
... direction based on the interaction words they ...the interaction word relationship ‘flows’ from the protein in the triplet that appears first in the sentence to the protein that ... See full document
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Network compression as a quality measure for protein interaction networks.
... a network [36] and Jukna et ...of network entropy based on topology configuration was used to segregate random network models ...definition based on local vertex ... See full document
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Neighbor overlap is enriched in the yeast interaction network: analysis and implications.
... such protein pairs to the high NO enrichment, we removed all pairs reported to be in the same complex ...is based on three datasets created by Pu et ...all protein pairs that were reported by ... See full document
9
A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients.
... a protein-protein interaction network ...a protein-protein interaction ...a network-based approach to integrate these signatures on the ... See full document
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Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions
... PPI network, in which PPIs are formed at all circadian phases (see Figure ...depend on a variety of factors such as spatial restrains, restriction to specific tissues, relative protein abundance, ... See full document
14
Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network.
... genes based on (i) the gene expression profiles, and (ii) the shortest path analysis of functional protein association ...existing protein-protein interaction data from STRING ... See full document
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Identifying hubs in protein interaction networks.
... definition based on topology of the protein interaction network leads to a clear coexpression-based separation between party and date ...hubs based solely on the ... See full document
10
Interface-resolved network of protein-protein interactions.
... interface-interaction network (IIN) to capture the specificity and competition between protein-protein interactions ...of network represents interactions between individual interfaces ... See full document
14
Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease.
... known protein complexes associated with many biological ...37 network biomarkers identified in our study may provide as potential therapeutic targets for PD applications ... See full document
17
Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.
... domain on each side of the ...a network diagram to visually explore interactions among all domains ...DDI interaction is based on sequence and ...such interaction between these ... See full document
10
Efficient identification of critical residues based only on protein structure by network analysis.
... of protein structures accomplishes protein function ...for protein function (to improve the sensibility of our method) is important to include in the analysis several protein ...for ... See full document
7
Investigating ego modules and pathways in osteosarcoma by integrating the EgoNet algorithm and pathway analysis
... background protein-protein interaction (PPI) network (PPIN) based on gene expression data and PPI data; extracting differential expression network (DEN) from the ... See full document
7
Computational analysis of HIV-1 resistance based on gene expression profiles and the virus-host interaction network.
... receptor protein- tyrosine kinase ubiquitination as an adaptor dependent upon its variant SH2 and RING finger domains ...was on 19,859 of the shortest paths, which suggests that it is important for HIV ... See full document
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Changes in protein interaction networks between normal and cancer conditions: Total chaos or ordered disorder?
... signaling protein molecules in normal and cancer conditions for five human tissues ...possible interaction among the proteins was constructed (Fig. 1) and the network properties for this ... See full document
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A computational method based on the integration of heterogeneous networks for predicting disease-gene associations.
... the protein interaction network rather than random selected n genes are used, and the irrelevant items and the irrelevant control set are constructed in the same way as ...coordinates on the ... See full document
10
Unveiling protein functions through the dynamics of the interaction network.
... for predicting the function of individual proteins, two main strategies have been followed so ...relies on the analysis of the protein itself: ...instead, based on high-throughput ... See full document
7
SUMOylation represses Nanog expression via modulating transcription factors Oct4 and Sox2.
... post-translational protein mod- ification and regulates many critical cellular ...Nanog protein compared with control cells, while knockdown of Sumo1/Ubc9 increased Nanog expres- sion ... See full document
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