[PDF] Top 20 Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition.
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Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition.
... PHD3 expression could revert MiaPaca2 cells from their mesenchymal-like morphology back to a more epithelial phenotype, we created a stable PHD3-Wt-overexpress- ing MiaPaca2 cell ...able ... See full document
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Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cells.
... filaments is a hallmark of epithelial cells whereas actin stress fi- bres are found in mesenchymal ...remodeling is mediated by the Rho GTPases and represents a basic mechanism critical ... See full document
12
MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4.
... the expression and function of b-catenin. Oct-4/b-catenin regulates the expression of Snail, ZEB1&2, three transcriptional factors in ...of mesenchymal cells, and become invasive and ... See full document
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A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.
... difficult to understand the molecular hierarchy and cooperation between ...SNAI1 expression and other molecular actors involved in EMT, which we further analysed in HTB129 and MDA231 ...(Fig. 3) ... See full document
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Inflammation Mediated Metastasis: Immune Induced Epithelial-To-Mesenchymal Transition in Inflammatory Breast Cancer Cells.
... (Fig 3). Most cell lines showed increased expression of EMT-regulating genes following treatment with immune cell ...response to LPS-CM were generally attenuated compared to TCR-CM, possibly ... See full document
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Partially Evoked Epithelial-Mesenchymal Transition (EMT) Is Associated with Increased TGFβ Signaling within Lesional Scleroderma Skin.
... performed to detect phospho-Smad2/3 (red) and K14 (green) in the epidermis of SSc patients and controls forearm skin sections (both n = 6, means of 5 high power views for each individual patient or ...used ... See full document
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A novel network profiling analysis reveals system changes in epithelial-mesenchymal transition.
... algorithm is only practical for medium-sized networks with up to several ...= 4, clock speed = 3.0GHz) | 3) for calculating 762 cancer cell line-specific gene networks from 13,508 | 762 gene ... See full document
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Role of Fos-related antigen 1 in the progression and prognosis of ductal breast carcinoma
... Fra-1 is associated with a more malignant phenotype and could play a pivotal role in cancer ...progression. 3 An association between Fra-1 and mes- enchymal characteristics in highly invasive breast cancer ... See full document
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Sorafenib inhibits epithelial-mesenchymal transition through an epigenetic-based mechanism in human lung epithelial cells.
... changes to EMT-associated genes during TGF-b1- induced ...E-cadherin expression is a prerequisite for EMT, invasion and metastasis of tumor ...pointed to progressive histone ... See full document
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Salt-induced epithelial-to-mesenchymal transition in Dahl salt-sensitive rats is dependent on elevated blood pressure
... at 4 6 C over- night, with the secondary antibody at room temperature for 30 ...Japan). To analyze the expression of E-cadherin and a- SMA in glomeruli and interstitium, 10 nonoverlapping high- power ... See full document
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Inhibition of pirfenidone on TGF-beta2 induced proliferation, migration and epithlial-mesenchymal transition of human lens epithelial cells line SRA01/04.
... pathway, to induce a variety of different responses ...needed to investigated the other molecular medhanisms of PFD for the inhibitory action for TGF-b2-induced fibrogenesis in lens epithelial ...PFD ... See full document
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Foxn1 Transcription Factor Regulates Wound Healing of Skin through Promoting Epithelial-Mesenchymal Transition.
... response to injury is followed by a wave of dermal repair ...EMT is rare, since epithelial cells rapidly lose expression of epidermal markers after transition and it is ... See full document
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The role of nuclear β-catenin accumulation in the Twist2-induced ovarian cancer EMT.
... due to the advanced stage of disease at diagnosis (stages ...the epithelial to mesenchymal transition (EMT) plays a critical role in the progression of ovarian carcinomas ...EMT ... See full document
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Deficiency of thioredoxin binding protein-2 (TBP-2) enhances TGF-β signaling and promotes epithelial to mesenchymal transition.
... There is the growing evidence that TBP-2 plays as a suppressor of ...TBP-2 is downregulated in various human cancer cells ...its expression is associated with responsiveness to ... See full document
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Col1A1 production and apoptotic resistance in TGF-β1-induced epithelial-to-mesenchymal transition-like phenotype of 603B cells.
... EMT is characterized by loss of epithelial cell polarity, loss of cell-cell contacts, and acquisition of mesenchymal markers and phenotypic traits that include increased cell ...E-cadherin is ... See full document
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TWIST1 a new determinant of epithelial to mesenchymal transition in EGFR mutated lung adenocarcinoma.
... treated during 4, 12, 24 and 48 hours with EGF at concentrations ranging from 5 to 120 ng/ ...mRNA expression occurred at 24 h, 5 ng/ml (data not ...ng/ml during 24 and 48 hours in ... See full document
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Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT).
... from epithelial tissues (carcinomas) [1]. The ability of cancer to spread, or metastasize, is responsible for the majority of deaths associated with cancer ...cells to metastasize, they must ... See full document
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14-3-3ε overexpression contributes to epithelial-mesenchymal transition of hepatocellular carcinoma.
... increased expression of 14-3-3e has been demonstrated in breast cancer, lung cancer, vulvar squamous cell carcinoma, follicular and papillary thyroid tumors, meningioma, and HCC [21,24,27– 30], although ... See full document
12
Neural crest stem cell population in craniomaxillofacial development and tissue repair
... gene expression in the facial mesenchyme (donor derived) and the ectoderm (host derived) were always characteristic of the ...gene expression programs characteristic of the quail even in tissues derived ... See full document
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J. Bras. Nefrol. vol.34 número4
... days) to serum deprived confluent monolayers HK2 cells in- duced ...due to calcium citrate administration, evidenced by lower expression of EMT markers, could not be exclusively explained by a TGF- β ... See full document
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