[PDF] Top 20 Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis.
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Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis.
... primary cervical cancer from the First Affiliated Hospital of Xi’an Jiaotong University between January 2010 and December ...period of recruitment, each subject was scheduled for an interview after ... See full document
10
CDHI promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer
... history of breast cancer is characterized by het- erogeneity within and between patients, since tumors with similar histopathological diagnosis can follow differ- ent clinical courses and show different responses ... See full document
9
Suppressor of cytokine signaling (SOCS) genes are silenced by DNA hypermethylation and histone deacetylation and regulate response to radiotherapy in cervical cancer cells.
... and cervical cancer are few in number. SOCS1may play a role in regu- lating the levels of the E7 protein of human papilloma virus, and affecting their transforming potential ...resulted ... See full document
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CDKN2A promoter methylation is related to the tumor location and histological subtype and associated with Helicobacter pylori fla A(+) strains in gastric
... light of studies demonstrating that genetic and epigenetic changes in gastric carcinoma differ, depending on the GC histological type (46, 47), we analyzed the data considering the adenocarcinoma subtypes ... See full document
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Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation.
... hyper-methylation of promoter regions is a well known mechanism of gene inactivation and suppression of gene expression, we investigated whether it was responsible for the lowered expression ... See full document
7
Hypermethylation of FOXP3 Promoter and Premature Aging of the Immune System in Female Patients with Panic Disorder?
... thymic function has been associated with inflammatory diseases [13,14,17] due to compensatory proliferative mechanisms in the periphery and increased Th1 and Th17 responses in relation to a ... See full document
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J. Bras. Patol. Med. Lab. vol.52 número1
... Introdução: Estudos realizados durante os últimos anos permitem considerar a infecção pelo papilomavírus humano (HPV) um fator etiológico para o câncer cervical. Apesar da íntima relação desse vírus com as regiões ... See full document
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Biomarkers of Cervical Carcinogenesis Associated with Genital Human Papillomavirus Infection
... 378 cervical samples from women attending to primary Health Clinics of the National Health Service and Gynaecological Outpatient Clinics and referred for HPV testing were analyzed between between January ... See full document
6
Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death.
... regulator of the Wnt signaling pathway. The Wnt-signaling pathway is implicated in other cancers [38,39] and suppresses apoptosis through both b- catenin dependent and independent pathways ...loss of ... See full document
15
Braz. Dent. J. vol.22 número5
... alterations in OM. It was hypothesized that methylation of these genes would silence protein expression and would contribute to OM ...detected in normal dental pulp cells than in OM. In ... See full document
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Aberrant promoter hypermethylation of ahr gene in human gliomas: methylation status analysis and clinicopathological significance
... Schematic of the theoretical basis of MethyLight ...level of the PCR amplification process or at the level of the probe hybridization process, or ...(U)] of the many theoretical ... See full document
206
DNA methylation analysis of the tumor suppressor gene CDKN2B
... degree of loss of protein produc- tion is not uniform throughout the tumor-cell population, unlike the one that is produced by the genetic changes (Jones and Baylin, ...expression of CDKN2B ... See full document
7
Constitutional and somatic methylation status of DMRH19 and KvDMR in Wilms tumor patients
... alterations in WT patients. One of these used MS-MLPA to analyze blood DNA samples from 437 children with non-syndromic WT and identified con- stitutional defects in 13 patients (3%), including six ... See full document
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Correlation of primary tumor size and axillary nodal status with tumor suppressor gene p53 in breast carcinoma
... markera p53 i veli~ine primarnog tumora, kao i odnos pozitivnih/negativnih vrijednosti markera u odnosu na ukupan broj ispitivanih tumora dojke. Na tabeli 1. prikazano je da je 16 (47,1%), od ukupno 34 tumora sa p53 ... See full document
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MLH1 promoter methylation frequency in colorectal cancer patients and related clinicopathological and molecular features.
... MLH1 promoter methylation in unselected CRC were included. In contrast, papers that selected subgroups were excluded (such as selected based on age, tumor staging and ulcerative colitis- ... See full document
9
Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.
... disappearance of c-H2AX is delayed until diplonema, or that cells with aberrantly elevated c- H2AX are preferentially ...depletion of diplotene cells observed in Arf-null mice (Figure ...Therefore, ... See full document
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The Human Homolog of Drosophila Headcase Acts as a Tumor Suppressor through Its Blocking Effect on the Cell Cycle in Hepatocellular Carcinoma.
... pathogenesis of hepatocellular carcinoma (HCC) is heterogeneous and extremely ...expression of the human homolog of Drosophila headcase (HECA homo) has been found in pancreatic, colorectal, ... See full document
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Determination Of Longevity Of Teeth In Buckets Of Loading Equipment In Coal Mines - A Case Study
... effects of machine scale, wear surface structure of the rolls, grinding pressures and rolls speed, gap settings, feed size distribution and moisture content for a range of ...wear of the ... See full document
11
Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.
... available in the different genotype cases. Obviously this was a smaller cohort of patients, therefore replication and validation of our results ...Replication in a bigger cohort would result ... See full document
9
Recurrent cervical tumor in the elderly
... 7. Kanlikama M, Mumbuc S, Bayazit Y, Sirikci A. Management strategy of mycobacterial cervical lymphadenitis. J Laryngol Otol 2000; 114(4): 274-278. 8. Weiler Z, Nelly P, Baruchin AM, Oren S. Diagnosis and ... See full document
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