[PDF] Top 20 Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine.
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Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine.
... of the most desirable qualities of a vaccine is long-term induction of an effective immune ...malaria vaccine because in many areas where malaria is endemic there are periods of high or low ... See full document
11
T cell responses induced by adenoviral vectored vaccines can be adjuvanted by fusion of antigen to the oligomerization domain of C4b-binding protein.
... enhance antibody responses in ...AdHu5-PfAMA16IMX313 and boosted with the same vaccine 8 weeks later (Ad-AdAMA1- IMX313 or ...Ad-AdAMA1-Nil). The vaccines induced PfAMA1- ... See full document
12
HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo.
... 0 and 2 (Figure 2). Mice receiving the protein boost were then immunized intramuscularly with 50 mg of HIV-1 MN gp120 formulated Titermix X-Gold adjuvantH at weeks four and ...sacrificed ... See full document
11
Diversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions.
... Circumsporozoite protein (CS) is a leading vaccine antigen for falciparum malaria, but is highly polymorphic in natural parasite ...populations. The factors driving this diversity are ... See full document
13
Human Infant Memory B Cell and CD4+ T Cell Responses to HibMenCY-TT Glyco-Conjugate Vaccine.
... vaccines to infant and toddler vaccination schedules has led to a reduction in invasive diseases such as meningitis and sepsis, which result from infection by ... See full document
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A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults.
... HIV-1 vaccine is likely to require the induction of broad and potent Env-specific antibody responses, CD8+ T lymphocyte responses that control HIV ... See full document
27
Immunopathogenesis of Hepatitis B Virus Infection and Related Complications
... infects and replicates in the liver. It is characterised by prolonged hepatitis B surface antigen seropositivity; this can lead to both cirrhosis and hepatocellular carcinoma ...(HCC). ... See full document
9
Vaccine Induced Antibody Response to Foot and Mouth Disease in Infectious Bovine Rhinotracheitis Seropositive Cattle
... Foot and mouth disease (FMD) and infectious bovine rhinotracheitis (IBR) are two important infectious diseases of ...are the most powerful tools to protect animals against ...challenge ... See full document
4
A Method To Find The Area Of Sector Without The Usage Of Angle Made By The Chord
... that to find the area of sector the angle made by the chord (that is chord which divides the circle) is ...in the below method we find the ratio of the ... See full document
2
DNA sequences encoding CD4+ and CD8+T-cell epitopes are important for efficient protective immunity induced by DNA vaccination with a Trypanosoma cruzi gene
... capture and detection monoclonal antibodies (MAbs) were R46A2 and biotinylated ...PBS and incubated overnight at ...removing the blocking solution, 0.05 ml of T-cell supernatant ... See full document
10
Antibody and T cell responses to Fusobacterium nucleatum and Treponema denticola in health and chronic periodontitis.
... of the current study include i) to characterize the T- dependent Ab and T cell responses to Fusobacterium nucleatum, an oral commensal, and Treponema ... See full document
10
A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4(+) and CD8(+) T Cell Responses
... able to induce Th1 cytokines. In order to analyze the vaccine induced cytokine secretion profile of BALB/c splenocytes incubated with the pooled HIV-1 peptides, we used ... See full document
13
Epstein-Barr virus but not cytomegalovirus is associated with reduced vaccine antibody responses in Gambian infants.
... of the 43 EBV-seropositive infants at eleven months of ...removed and DNA was isolated into 50 m l using the DNA Mini Kit reagents ...[39] and Namalwa cells [40] using similar methods. ... See full document
8
Impairment of the Plasmodium falciparum erythrocytic cycle induced by angiotensin peptides.
... but the signaling pathways activated by this receptor are not well established ...II and Ang-(1–7) inhibit PKA activity in an A779-sensitive manner similar to inhibition of the ...P. ... See full document
9
Co-administration of plasmid-encoded granulocyte-macrophage colony-stimulating factor increases human immunodeficiency virus-1 DNA vaccine-induced polyfunctional CD4
... (HIVBr18)-induced T-cell responses. Two weeks after the last immunisation with HIVBr18 co- administrated with pVAX1 or pGM-CSF, pooled spleen cells from six BALB/c mice were cultured in ... See full document
7
Fragmentation of SIV-gag vaccine induces broader T cell responses.
... of the experimen- tal plan and reagents ...for the generation of SIV-specific memory T ...generated by culture of monocytes with GM-CSF and IL-4 for 7 ...hours and matured ... See full document
13
Iliano V Coutinho-Abreu, Marcelo Ramalho-Ortigao
... P. falciparum-derived TBV candidate - Pfs48/45 - Another TBV candidate to control spread of ...Pfs48/45. The Pfs48/45 gene encodes a unique protein that migrates as a double band under non-re- ... See full document
12
UNIVERSIDADE FEDERAL DO PARÁ INSTITUTO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS FARMACÊUTICAS
... in the treatment of malaria, uterus infections, gastritis, anemia, respiratory problems, among other ...ailments. The objectives of this study were to carry out the phytochemical study of ... See full document
140
Dietary restriction abrogates antibody production induced by a DNA vaccine encoding the mycobacterial 65 kDa heat shock protein
... in the innate immune system, for example, lysozyme production by monocytes and polymorphonuclear cells is decreased, complement factors are diminished in both concentration and activity ... See full document
8
Immunization against Leishmania major infection using LACK- and IL-12-expressing Lactococcus lactis induces delay in footpad swelling.
... expressing the protective Leishmania antigen LACK in three different subcellular locations and a strain of ...than the previously described strain expressing the murine wild-type gene ... See full document
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