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[PDF] Top 20 Regulation of STEAP1 gene and its clinical significance in human prostate cancer

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Regulation of STEAP1 gene and its clinical significance in human prostate cancer

Regulation of STEAP1 gene and its clinical significance in human prostate cancer

... prevalence of PCa can be classified as endogenous (age, family history, ethnicity, hormones and oxidative stress) or exogenous (dietary factors, physical inactivity, obesity, environmental factors, ... See full document

224

HER2 status in colorectal cancer: its clinical significance and the relationship between HER2 gene amplification and expression.

HER2 status in colorectal cancer: its clinical significance and the relationship between HER2 gene amplification and expression.

... methods and criteria as ours, and reported that HER2 positivity was observed in ...12.4% of rectal biopsy samples and 26.7% of rectal resected ...positivity in resected ... See full document

9

Expression of prostate-specific membrane antigen in lung cancer cells and tumor neovasculature endothelial cells and its clinical significance.

Expression of prostate-specific membrane antigen in lung cancer cells and tumor neovasculature endothelial cells and its clinical significance.

... The clinical significance of PSMA expression in tumor NECs is not fully ...invasion, and me- tastasis ...percentage of patients with PSMA-positive cells has no significant ... See full document

8

Serum levels of the cancer-testis antigen POTEE and its clinical significance in non-small-cell lung cancer.

Serum levels of the cancer-testis antigen POTEE and its clinical significance in non-small-cell lung cancer.

... type of protein that is expressed in normal adult tissue only in the testis as well as a variety of tumors of different histological ...origins. In view of their pattern ... See full document

10

Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1.

Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1.

... Prostate cancer is a relatively common malignant cancer and the second most commonly diagnosed cancer in men ...the clinical treatment of prostate ... See full document

8

Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer

Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer

... discovered in 1985, as an enzyme cap- able of extending telomeric repeat sequences; and in 1989, telomerase activity was reported for the first time ...component of telomerase was only ... See full document

12

Estrogenic Regulation of the SCF/c-KIT System in Prostate Cells: a Relationship with Prostate Cancer?

Estrogenic Regulation of the SCF/c-KIT System in Prostate Cells: a Relationship with Prostate Cancer?

... Prostate cancer (PCa) is the most common type of oncological disorder in men, for which an increasing incidence has been ...Development and progression of PCa have been highly ... See full document

110

Transcriptional and epigenetic regulation of KIAA1199 gene expression in human breast cancer.

Transcriptional and epigenetic regulation of KIAA1199 gene expression in human breast cancer.

... (MatInspector and Alibaba2) to predict transcription factor binding sites based on DNA ...elements in the KIAA1199 promoter, including AP-1, NF-kB, and Twist-1, which are situated in the ... See full document

15

Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms

Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms

... that STEAP1 is overexpressed in several kinds of tumors, but the mechanisms underlying its overexpression remain to be ...if STEAP1 expression would be regulated by post-transcriptional ... See full document

10

Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.

Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.

... up-regulation of aminoacyl tRNA synthetases in LNCaP, and their expression in prostate ...expression of aminoacyl-tRNA synthetases identified from iTRAQ ...proteins ... See full document

12

Identification of prognostic molecular features in the reactive stroma of human breast and prostate cancer.

Identification of prognostic molecular features in the reactive stroma of human breast and prostate cancer.

... breast, prostate and pancreatic carci- noma, can be associated with massive ECM deposition, referred to as ...grow and disseminate, it is widely held that rational anticancer therapeutic design ... See full document

12

STEAP1 exepression in prostate cancer and its regulation by androgens

STEAP1 exepression in prostate cancer and its regulation by androgens

... compartment of the prostate epithelium and produce prostatic secretions and proteins like prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP) (McNeal 1968; ... See full document

62

Genetic and epigenetic mechanisms involved in regulation of STEAP1 gene expression in LNCaP prostate cancer cells

Genetic and epigenetic mechanisms involved in regulation of STEAP1 gene expression in LNCaP prostate cancer cells

... Prostate cancer is the second most frequently diagnosed type of cancer and the fifth leading cause of cancer death in men ...worldwide. Prostate ... See full document

78

Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse.

Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse.

... subtype in normal human ...regulated in various tumor types and therapeutic somatostatin analogs binding to SSTR2 are in clinical ...use. In prostate cancers highly ... See full document

10

The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.

The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.

... observations and mouse models have suggested that inflammation can be ...critical in leukocyte trafficking, we hypothesized that chemokines play essential roles in inflammation-associated ... See full document

12

Variants of the PPARD gene and their clinicopathological significance in colorectal cancer.

Variants of the PPARD gene and their clinicopathological significance in colorectal cancer.

... (p.R258Q) in the primary colon cancer cell line SW480 and not in lymph node metastatic cell line ...feature of SW480 and SW620 cell lines is that they are derived from primary ... See full document

8

Prognostic Value of Morphologic and Clinical Parameters in pT2 - pT3 Prostate Cancer

Prognostic Value of Morphologic and Clinical Parameters in pT2 - pT3 Prostate Cancer

... research of new prognostic criteria with clinical applicability that precisely define recurrence risk, survival rate and the appropriate medical orientation, for both clinical follow-up ... See full document

12

Int. braz j urol.  vol.36 número6

Int. braz j urol. vol.36 número6

... timing of cystectomy in T1 bladder cancer is a matter of debate since ...series of 523 patients and analyze variables which may help with the deci- sion to remain conservatively, ... See full document

3

Crystal Structure of Crataeva tapia Bark Protein (CrataBL) and Its Effect in Human Prostate Cancer Cell Lines.

Crystal Structure of Crataeva tapia Bark Protein (CrataBL) and Its Effect in Human Prostate Cancer Cell Lines.

... structure of mature CrataBL consists of a single polypeptide 164 or 165 amino acid long, present in at least two distinct isoforms, differing in positions 31 (Pro/Leu); 92 (Ser/Leu); 93 ... See full document

14

Chemical Constituents from Solanum glabratum Dunal var. sepicula

Chemical Constituents from Solanum glabratum Dunal var. sepicula

... n-butanol and remaining aqueous fractions were tested for their cytotoxic activity against human prostate cancer cell line (PC3) using 3-[4,5-dimethylthiazol-2-yl]- 2,5-diphenyltetrazolium ... See full document

11

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