Top PDF Remodeling of the methylation landscape in breast cancer metastasis.
Remodeling of the methylation landscape in breast cancer metastasis.
... for methylation (n = 44) and gene expression analysis (n = 36) were collected at the time of primary surgery and banked at ...a breast cancer pathologist and microdissected to obtain ...
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Clinical and Prognostic Significance of Preoperative Plasma Fibrinogen Levels in Patients with Operable Breast Cancer.
... Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females worldwide, with an estimated ...deaths in 2012, It alone ...
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Methylation of the claudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer.
... to the other cell lines. Re-expression of claudin 1 protein on the surface of treated HCC1569 and MDA‑MB‑453 cells was confirmed by flow ...increase in claudin 1 signal in both ...
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Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model.
... Brain metastasis of breast cancer is an important clinical problem, with few therapeutic options and a poor ...(MLK3) in controlling the in vitro migratory capacity ...
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Angiotensin II facilitates breast cancer cell migration and metastasis.
... levels of ICAM-1 in breast tumors are associated with a more aggressive phenotype [30], and by studies highlighting the importance of vascular cell adhesion molecules in ...
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Linfonodos axilares em pacientes com câncer de mama: avaliação ultrassonográfica.
... staging of patients with early-stage breast cancer is essential in the treatment ...times in association with fine-needle aspiration biopsy or core needle ...However, the ...
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METÁSTASES GÁSTRICAS DE CÂNCER DE MAMA: QUANDO A GASTRECTOMIA ESTÁ INDICADA?.
... Background: Breast cancer is the most common malignant neoplasm in the female ...for metastasis, and can show up many years after initial diagnosis and treatment of ...
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Radiol Bras vol.49 número5
... pattern of male breast cancer follows that of female breast cancer in that the bones, lungs, and liver are the most common ...Splenic metastasis ...
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Radiol Bras vol.49 número5
... The breast tumor was classified as clinical stage IV, with metastasis to the lungs (lymphangitis carcinomatosa identified on CT) and bones, and surgery for the breast lesion was ...
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Bridging cancer biology with the clinic: relative expression of a GRHL2-mediated gene-set pair predicts breast cancer metastasis.
... characterization of crucial gene target(s) that will allow focused therapeutics development remains a ...interrogated the putative therapeutic targets associated with the transcription factor Grainy ...
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Estudo do papel da ADAM9 na disseminação tumoral via sistema linfático: Possível alvo farmacológico
... but the last is preferred by breast tumor ...involved in cell adhesion and proteolysis, causing metastasis, such as ADAMs, a family of multi-domain and multi-functional proteins that ...
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Rb suppresses collective invasion, circulation and metastasis of breast cancer cells in CD44-dependent manner.
... Loss of Rb expression promotes metastatic behavior in human breast cancer cell ...quantification of mammosphere-forming potency of MCF7ras and T47D cells with Rb ...Morphology ...
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Single Jejunum Metastasis from Breast Cancer Arising Twelve Years after the Initial Treatment
... examination of the tumor revealed an undifferentiated carcinoma (T3N0Mx). The lack of dysplasia and atypia of the intestinal epithelium and the normal glands surrounding ...
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Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines.
... expression of CDKN2A and MTAP; however. the MTAP promoter was partially ...deletion of CDKN2A in this cell line but not a deletion of CDKN2B or INK4A genes, which are closely located on ...
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Quantitative LC-MS/MS Analysis of Proteins Involved in Metastasis of Breast Cancer.
... purpose of this study was to develop quantitative liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for the analysis of proteins involved in metastasis of ...
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Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.
... function of Rrp1b and its exact role in metastasis remain unclear at this ...regulator of Rap1 by serving as a GAP for Rap1 ...implicated in maintaining the integrity of ...
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Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis
... overt metastasis remains largely unknown, in large part due to the lack of appropriate animal models that closely reca- pitulate the ...mimic the activation of indolent ...
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J. Appl. Oral Sci. vol.23 número1
... xenograft, breast cancer development has shown a low success rate in most trials due to the technically limited occurrence of mammary glands in neonatal ...inoculation of ...
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Roadmap of DNA methylation in breast cancer identifies novel prognostic biomarkers
... with the advent of high-throughput technolo- gies, gene expression profiling has enabled a more com- prehensive view of the molecular identity of breast ...6–8]. Breast ...
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WNT5A inhibits metastasis and alters splicing of Cd44 in breast cancer cells.
... define breast cancer metastasis ...performed in this report provide a comprehensive view of changes in gene expression elicited by over-expression of WNT5A in ...
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