[PDF] Top 20 Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America
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Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America
... Background: In Honduras, chloroquine and primaquine are recommended and still appear to be effective for treatment of Plasmodium falciparum and Plasmodium ... See full document
7
Emerging Plasmodium vivax resistance to chloroquine in South America: an overview
... P. vivax isolates from Madagascar and Cambodia, obtained directly from patients’ blood samples and from the monkey-adapted Belem ...strain. In doing so, these authors demonstrated that it is ... See full document
6
Increased prevalence of Plasmodium falciparum malaria in Honduras, Central America
... P. vivax was present in 79% (63/80) of the in- fected rural patients and 100% (15/15) of the infected city ...present in 21% (17/80) of the rural patients. No patient was in- ... See full document
3
A new challenge for malaria control in Brazil: asymptomatic Plasmodium infection - A Review
... malaria in Brazil date from the XVI century, arising as a natural con- sequence of the European ...present in all the Brazilian state capitals (Camargo ...occurring in Brazil every year, ...erupted ... See full document
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Susceptibility of Anopheles campestris-like and Anopheles barbirostris species complexes to Plasmodium falciparum and Plasmodium vivax in Thailand
... concern in international public health. It is endemic in more than 109 countries and threatens the health of about 50% of the world’s popula- tion (350-500 million people/year), particularly ... See full document
8
Dihydrofolate-Reductase Mutations in Plasmodium knowlesi Appear Unrelated to Selective Drug Pressure from Putative Human-To-Human Transmission in Sabah, Malaysia.
... diversity and absence of putatively neutral synonymous varia- tion in the pfhdfr region in Sabah is consistent with purifying selection acting upon a gene whose product has an important functional ... See full document
19
The Duffy binding protein as a key target for a Plasmodium vivax vaccine: lessons from the Brazilian Amazon
... Cross-sectional and cohort studies carried-out in the Amazon area provide evidence that the majority of people naturally-exposed to ...P. vivax do not develop antibodies that inhibit the DB- PII-DARC ... See full document
10
Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax infections
... 2000) and high plasma levels of these cytokines are found at diagnosis, even in uncomplicated malaria cases (Baptista et ...roles in the immune response against ...P. falciparum in- ... See full document
9
Optimising strategies for Plasmodium falciparum malaria elimination in Cambodia: primaquine, mass drug administration and artemisinin resistance.
... diagrammatically in figure 1 and as equations in Supporting Information ...P. falciparum life cycle in humans, antimalarial drug action, resistance to artemisinin ... See full document
10
Saude soc. vol.19 número1
... dios vivax, malariae, e ovale poderiam ter coevoluído com a espécie humana ou ter atingido esta durante as fases mais antigas da evolução do gênero ...Plasmódio falciparum teria sido transmitido aos humanos ... See full document
20
Differing patterns of selection and geospatial genetic diversity within two leading Plasmodium vivax candidate vaccine antigens.
... tree-based and statistical methods [92], we found that pvcsp, but not pvmsp-1, showed strong clustering by geography (Tables 3–4 and Figures ...described in Duffy Binding Protein and ... See full document
17
Luiz Hildebrando P da Silva
... antibodies in asymptomatic sera. In P. falciparum, PfHSP70-1 was identified using a proteomic approach as part of Maurer´s clefts (Vincensini et ...abundant in the cytosol and ... See full document
7
Plasmodium vivax Transmission in Africa.
... Malaria in sub-Saharan Africa has historically been almost exclusively attributed to Plasmo- dium falciparum ...diagnostic and surveillance systems in much of sub-Saharan Africa are not ... See full document
27
KF Vasconcelos, CV Plowe, CJ Fontes, D Kyle, DF Wirth, LH Pereira da Silva, MG Zalis
... malaria in the Amazon ...years in many regions of the Amazon and PS is no longer recom- mended for use in ...Brazil. In vitro resistance to pyrimethamine and cycloguanil ... See full document
8
Unexpectedly long incubation period of Plasmodium vivax malaria, in the absence of chemoprophylaxis, in patients diagnosed outside the transmission area in Brazil
... days) in 14% of the P. vivax malaria patients seen at IPEC, in Rio de Janeiro, may indicate the importance of monitoring these characteristics worldwide, as it may represent an evolutionary change ... See full document
5
Cad. Saúde Pública vol.30 número7
... cases in the SIVEP-Malaria ...sensitive and timely informa- tion system with good ...rate in the study is the patient’s mobility in the endemic area, and the same patient may have had ... See full document
15
Cad. Saúde Pública vol.22 número12
... for Plasmodium falciparum resistance to chloroquine in isolates from the Brazilian Amazon and to identify polymor- phisms in the pfmdr1 gene, codons 184, 1042, and 1246, ... See full document
9
Sequence polymorphisms in Pvs4845 and Pvs47 gametocyte and gamete surface proteins in Plasmodium vivax isolated in Korea
... forward and reverse primers were 5′-CACGCAGATTGATGTCGC-3′ (CM000453, 289234-289251) and 5′-CAAACAGGTGCACGCGC-3′ (CM000453, 290823-290839), ...forward and reverse primers were 5′-CACACCACCGCAAACAGG-3′ ... See full document
9
Anopheles darlingi bionomics and transmission of Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae in Amerindian villages of the Upper-Maroni Amazonian forest, French Guiana
... areas in South ...increase in July and a peak in August, at the beginning of the dry ...HBR and malaria ...caught, and detection of infected mosquitoes both dur- ing the rainy ... See full document
9
Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression
... this drug, though to a limited ...hsp86) in a northern blot based approach, after a 6h MQ treatment ...seen in response to MQ does not exclude more significant responses upon exposure to other ...P. ... See full document
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