[PDF] Top 20 RNA Interference: a Promising Therapy for Gastric Cancer
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RNA Interference: a Promising Therapy for Gastric Cancer
... Asian Paciic Journal of Cancer Prevention, Vol 15, 2014 and progression processes in normal and tumor tissues (Fire et al., 1998), thus, several investigators have focused their attention to the possible antitumor ... See full document
7
CIAPIN1 gene silencing enhances chemosensitivity in a drug-resistant animal model in vivo
... SGC7901/Adr gastric cancer cells (10,11) and HL-60/Adr leukemia cells (12) in which CIAPIN1 confers resistance by upregulating MDR1 expression ...breast cancer cells ...by RNA ... See full document
6
Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer.
... both cancer cell survival and cancer cell death after drug treatment [22,23], we further evaluated the contribution of this process to the effect of vorinostat on gastric cancer cell ... See full document
10
Co-delivery of doxorubicin and SATB1 shRNA by thermosensitive magnetic cationic liposomes for gastric cancer therapy.
... target therapy, chemotherapy is still one of the important approaches for gastric cancer ...chemo- therapy are often unsatisfied and could not significantly improve the prognosis of ... See full document
10
α-Fetoprotein promoter-driven Cre/LoxP-switched RNA interference for hepatocellular carcinoma tissue-specific target therapy.
... The AFP-Cre/LoxP-shRNA system was successfully established (Fig. 3A). The CMV-eGFP indicator inside could well indicate whether the system worked as desired (Fig. 3B,C). The GFP fluorescence diminished after AFP-Cre and ... See full document
12
Salivary microRNAs as promising biomarkers for detection of esophageal cancer.
... tract. Cancer tissue and plasma miR-21 were significantly upregulated in EC, gastric cancer, liver cancer, pancreatic cancer, bile duct cancer, colorectal cancer, ...of ... See full document
12
Targeting PPM1D by lentivirus-mediated RNA interference inhibits the tumorigenicity of bladder cancer cells
... bladder cancer (BC) remains largely ...hairpin RNA (shRNA) targeting PPM1D were used to explore the effects of PPM1D knockdown on BC cell proliferation and ...a promising therapeutic strategy for the ... See full document
6
Gastric cancer management : kinases as a target therapy
... maintenance therapy compared to continuation of first- line chemotherapy ...potentially promising strategy resides in the integration of immunotherapeutic drugs with molecularly tar- geted ... See full document
10
INDUCING APOPTOSIS IN CANCER THERAPY
... of cancer cells with tumour necrosis factor - can induce an apoptotic signal leading to the death of these cells; however, many malignancies are resistant to the effects of TNF- α ... See full document
5
PD-L1 and Survival in Solid Tumors: A Meta-Analysis.
... [40, 41]. A decade ago some studies reported that blockade of PD-L1 could improve antitumor immunity [42–44]. Recently, several studies show that therapies targeting PD-L1/PD-1 display clinical responses in patients with ... See full document
15
Association between alcohol consumption and cancers in the Chinese population--a systematic review and meta-analysis.
... Ethanol itself is not carcinogenic. However, its first metabolite (acetaldehyde) has recently been shown to be a local carcinogen in humans [6]. Moreover, alcohol consumption is an important risk factor for numerous ... See full document
11
Gastric cancer after gastroplasty for morbid obesity.
... Este artigo apresenta o caso de uma paciente que desenvolveu câncer no remanescente gástrico cinco anos após a gastroplastia.. RELATO DO CASO.[r] ... See full document
2
Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas.
... Gastric cancer remains the second leading cause of cancer-related death in the ...for gastric cancer, generates high levels of reactive oxygen species ...9 gastric cancer ... See full document
10
RNA and DNA aptamers as potential tools to prevent cell adhesion in disease
... evolve RNA aptamers that bind to P-selectins on cell surfaces and pre- vent the binding of natural ligands on com- municating cells resulting in inhibition of cell adhesion ...(13). RNA and DNA aptamers ... See full document
6
Head and Neck Cancer Treatment with Particle Beam Therapy
... and therapy process at Berkeley center. Proton therapy started at Uppsala/Sweden in 1957 while the same treatments activities started at Harvard cyclotron in the year of 1961 (more or less 9000 patients ... See full document
6
Cytogenetic characterization and evaluation of c-MYC gene amplification in PG100, a new Brazilian gastric cancer cell line
... in gastric carcinogenesis, other less frequent indings such as 5p deletion and trisomy 16 open new perspectives for future studies concerning this speciic ... See full document
6
Histone deacetylase HDAC4 promotes gastric cancer SGC-7901 cells progression via p21 repression.
... in gastric carcinoma [21], whereas the loss of p21 expression along with increased p53 detection is associated with poor prognosis and decreased overall survival in gastric cancer ...the ... See full document
8
Chemotherapy versus support cancer treatment in advanced gastric cancer: a meta-analysis
... chemo- therapy and support treatment in patients with advanced non-resect- able gastric cancer in a systematic review and meta-analysis of ran- domized clinical trials that included a comparison of ... See full document
10
Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro Xia Yang, Feng Qian, Hai-Yang He, Kai-Jun Liu, Yuan-Zhi Lan, Bing Ni, Yi Tian, Xiao-Lan Fu, Ji Zhang, Zi-Gang Shen, Jian Li, Yi Yin, Jin-Tao Li and Yu-
... Certain biological response modifiers (BRMs) are thought to be essential for the induction of protective and therapeutic antitumor immunity. Thymosin alpha 1 (Tα1) was described in the 1970s as a clinically applicable ... See full document
9
MicroRNA let-7f inhibits tumor invasion and metastasis by targeting MYH9 in human gastric cancer.
... breast cancer cells ...migrating cancer cells [46]; mts1 influences both the assembly behavior of Figure ...in gastric tumor ...distant gastric metastasis specimens is higher than that in ... See full document
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