[PDF] Top 20 The role of hnRPUL1 involved in DNA damage response is related to PARP1.
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The role of hnRPUL1 involved in DNA damage response is related to PARP1.
... recruitment of repair proteins to damage sites ...ribosyl)ation is a quick and transient response to DNA damage [16], and previous studies have shown that a large ... See full document
10
The RecA-Dependent SOS Response Is Active and Required for Processing of DNA Damage during Bacillus subtilis Sporulation.
... committed to sporulate no longer replicate the chromosomes in the mother cell and the forespore compartments [2, 23], a recombination-repair role for RecA in this develop- ... See full document
13
CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response.
... consists of four members, p16INK4a, p15INK4b, p18INK4c and p19INK4d which play a redundant role as CDK4/6 ...some of them [25]. Interestingly, p16INK4a and p19INK4d (p19) were linked to ... See full document
14
Initiation of genome instability and preneoplastic processes through loss of Fhit expression.
... mechanisms involved in Fhit support of DNA replication progression, we considered the observation that depletion of dNTP pools by hydroxyurea exposure equalized DNA ... See full document
16
Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells.
... order to characterize the impact of LigI-deficiency on gene expression we compared total RNAs from ...by the microarray technology. By this approach we identi- fied a total of 2114 ... See full document
18
Chromatin relaxation-mediated induction of p19INK4d increases the ability of cells to repair damaged DNA.
... that the transcription factor E2F1 plays a role in response to disturbed chromatin structure, motivated either by DNA damage or any other origin, connecting the ... See full document
13
Use of the Comet Assay to study the role of MGMT, MMR and p53 in the repair of alkylating DNA damage
... p53 is encoded by the TP53 gene and has a relevant role in cancer being referred to as the “guardian of the genome” due to the many functions it ... See full document
99
Conserved and distinct modes of CREB/ATF transcription factor regulation by PP2A/B56gamma and genotoxic stress.
... and the closely related proteins CREB (cyclic AMP resonse element binding protein) and CREM (cyclic AMP response element modulator) constitute a subfamily of bZIP transcription factors that ... See full document
10
Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks.
... USP5 is one of the DUBs and it disassembles unanchored polyubiquitin chains by a sequential exo mechanism ...[27]. To investigate whether USP5 is involved in the ... See full document
11
DNA DAMAGE INDUCED BY ACRYLAMIDE: ROLE OF GENETIC POLYMORPHISMS IN DNA DAMAGE LEVELS Marta Sofia Pereira Pingarilho Fazendeiro
... distribution of the polymorphisms involved in detoxification pathways and its association with the levels of GA-induced SCE is presented in Table ...V.5. In ... See full document
229
ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... reported to occur during active visceral leishmaniasis and some factors such as the cytokine profile may be involved in this ...process. In the mouse model of cutaneous ... See full document
6
The cellular phenotype of Roberts syndrome fibroblasts as revealed by ectopic expression of ESCO2.
... by the topoismerase II inhibitor etoposide, which stabilizes a topoisomerase II-DNA complex and prevents religation of the DNA after the enzyme has generated a double strand ... See full document
11
Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.
... (BER) is the primary cellular mechanism to address DNA base damage, which results from both endogenous and exogenous agents such as reactive oxygen species, alkylating agents, and ... See full document
7
Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.
... blotting is a traditional method for detecting such ...amounts of DNA. Therefore, a new method is needed for detecting breaks in ...Because the ChIP assay is a relatively ... See full document
18
Rtt107 phosphorylation promotes localisation to DNA double-stranded breaks (DSBs) and recombinational repair between sister chromatids.
... their DNA that are either induced as a consequence of the action of exogenous agents, such as different drugs causing DNA damage, or as a consequence of the cell’s ... See full document
11
Bruna Prati, Bruna Marangoni, Enrique Boccardo
... types is the etiological factor of cervical cancer and a major cause of other epithelial malignancies, including vulvar, vaginal, anal, penile and head and neck carci- ...through the ... See full document
9
The transcriptional response of Caenorhabditis elegans to Ivermectin exposure identifies novel genes involved in the response to reduced food intake.
... shown to be up-regulated in response to other xenobiotics, but the phenotype of the exposed worms was not reported ...1 of CYP4V2 is a homologue of C. ... See full document
11
Synthesis Of Arts In Architecture Of Uzbekistan Of The Ancient Period
... on the location of a sculpture in the overall composition of certain structures, on the skills of masters belonging to different art ...schools. In rare ... See full document
8
Mechanisms that enhance sustainability of p53 pulses.
... protein is one of the most important tumor suppressors that is mutated in more than half of all human cancers ...[1]. The p53 protein regulates key functions, such as ... See full document
11
CSB-PGBD3 Mutations Cause Premature Ovarian Failure.
... construction of CSB-PGBD3-eGFP, CSB-PGBD3-RFP, Flag-CSB-PGBD3 and OGG1-GFP. The diagram of wild type and 3 mutant (ENST00000515869: ...plasmid of CSB-PGBD3-pEGFP-N1 (A), CSB-PGBD3-RFP (B), ... See full document
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