[PDF] Top 20 Role of gap junction protein connexin43 in astrogliosis induced by brain injury.
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Role of gap junction protein connexin43 in astrogliosis induced by brain injury.
... Increased Astrogliosis in the Absence of Astrocytic Cx43 To determine whether the injury response due to stab wound is affected by Cx43 expression, we carried out the same needle ... See full document
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Gap junction protein connexin43 exacerbates lung vascular permeability.
... flux by sealing the intercellular gaps through adhesion of apposing junctional proteins ...the gap junctions contribute a significant increment in adhesive function (beyond the cadherin-based ... See full document
11
The Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid Oxidation
... mechanism of cellular injury induced by elevated oxidative stress which results in the production of lipid peroxides and their byproducts that lead to the loss of membrane ... See full document
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Metallothionein (MT) -I and MT-II expression are induced and cause zinc sequestration in the liver after brain injury.
... expression of MT-I/II is thought to decrease cytoplasmic concentrations of free ...amount of zinc bound to MT-I/II is below maximum capacity ...involved in zinc sequestration, the ratio ... See full document
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Identification of a protein kinase activity that phosphorylates connexin43 in a pH-dependent manner
... grown in E. coli DH5 a. The fusion protein was expressed by incubating the bacteria in LB broth with ...washed in Tris-buffered saline (TBS) and resuspended in TBS (1/10 ... See full document
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Spatiotemporal correlations between blood-brain barrier permeability and apparent diffusion coefficient in a rat model of ischemic stroke.
... modification of D-CEMRI [21,25] as described in our recent studies ...mmol/kg of gadolinium-diethylene-triamine-pentaa- cetic acid (Gd-DTPA, MW = 938 Da; Bayer Healthcare) as a bolus into the femoral ... See full document
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Regulation of neurogenesis by calpains: revelance for post-injury brain repair
... percentage of new neurons in the DG after lesion, they could still be more functional and better integrated in the neuronal ...involved in learning and memory, we decided to investigate ... See full document
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Role of morphine preconditioning and nitric oxide following brain ischemia reperfusion injury in mice
... increase in cardiac tissue tolerance against ischemia, even during 24 hr of morphine withdrawal period ...effective in heart preconditioning among aged mice while acute opioid treatment had no effect ... See full document
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Leptin Downregulates LPS-Induced Lung Injury: Role of Corticosterone and Insulin
... regulated by immune and endocrine systems because there is a regulatory loop between the HPA axis and circulating ...effects of leptin on the corticosterone levels have been ...administration of ... See full document
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Efficacy of curcumin to reduce hepatic damage induced by alcohol and thermally treated oil in rats
... alterations of all measured ...increase in serum aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP) and total bilirubin, together with a significant decrease in the ... See full document
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Regulation of injury-induced neurogenesis by Nitric Oxide
... many of the studies with NO-NSAID have been essentially about its anti-inflammatory ...studies in the literature have reported the anti-inflammatory effect of NO-NSAID in animal models ... See full document
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Orientador: Doutor José Manuel Fuentes Rodríguez Co-orientador: Doutora Mireia Niso Santano Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universidad de Extremadura, Espanha
... example of neurodegenerative disorder with a critical role of oxidative stress in its etiopathogenesis (Kalia, ...factors of PD, such as mutations in Parkin, PINK1, and DJ-1 as ... See full document
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Testing the ability of non-methylamine osmolytes present in kidney cells to counteract the deleterious effects of urea on structure, stability and function of proteins.
... 25uC by the method of Maurel & Douzou ...pre-incubated in a given concentration of urea, each stabilizing osmolyte (myo-inositol, sorbitol and taurine) alone and in combined ... See full document
12
Chosen aspects of thermo-mechanical phenomena in resin bonded sands by use of Hot Distortion tests
... Two thcrmic sources (clcctric and gascous) to sarnplc hcating was testcd and analyscd. I t was intmduced the cxtended measurement and recording of choscn parameters. i.e, va[r] ... See full document
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Rev. bras. ter. intensiva vol.25 número1
... speciicities of these biomarkers have been established, their application is generally easy because they can be measured when samples are collected from patients (regardless of the clinical status) and ... See full document
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Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice.
... the role of HIF-1a in chronic alcohol- induced liver injury despite a similar Lieber-DeCarli liquid diet in both studies [6, ...used in these studies (normal C57BL/6 mice ... See full document
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Perivascular delivery of Notch 1 siRNA inhibits injury-induced arterial remodeling.
... increase in Notch signaling components [10] [16] ...increase in the expression of the Notch 1 versus the Notch 3 receptor ...increase in Notch1 receptor expression is predominantly localized ... See full document
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Antithrombotic effect of Lonomia obliqua caterpillar bristle extract on experimental venous thrombosis
... venom of Lonomia obliqua caterpillar may induce a hemorrhagic syndrome in humans, and blood incoagulability by afibrinogenemia when intravenously injected in laboratory ...activities of ... See full document
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Male-Specific Alleviation of Iron-Induced Striatal Injury by Inhibition of Autophagy.
... concerned. In a rat model involving infusion of ferrous citrate (FC) that simulates iron accumulation after hemorrhage, a higher degree of autophagy associated with higher injury severity was ... See full document
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Sulfasalazine-induced renal and hepatic injury in rats and the protective role of taurine
... University of Medical Sciences, Shiraz, Iran. Animals were housed in plastic cages over hardwood ...temperature of 21‑23°C with a 40% of relative ... See full document
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