Top PDF Role of Oxidative Stress on Vaginal Bleeding during The First Trimester of Pregnant Women

Role of Oxidative Stress on Vaginal Bleeding during The First Trimester of Pregnant Women

Role of Oxidative Stress on Vaginal Bleeding during The First Trimester of Pregnant Women

The current study showed that serum TOS levels were higher and serum TAC levels were lower in pregnant women with vaginal bleeding when com- pared to women with normal-ongoing pregnancies of similar gestational age in the irst trimester. Vaginal bleeding is common complication in the irst trimester of pregnancies and may be an early marker for placental dysfunction. About half of pa- tients presenting with bleeding have miscarriage (8). Still, the precise etiology of spontaneous abor- tion remains unclear. About 50% of all spontane- ous abortions are associated with chromosomal abnormalities. The remaining 50% of the causes may be preventable (9). Pregnancies with vagi- nal bleeding have increased risk of other adverse outcomes such as placental abruption, low birth weight and preterm delivery (10-12). There is now compelling evidence that oxidative stress is one of the main underlying mechanisms in the pathogen- esis of spontaneous abortion (13). Oxidative stress is well known to initiate the caspase cascade lead- ing to cell death in other systems. Concentrations of lipid peroxides increase in the decidua of wom-
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Ion Exchange Properties of the Erythrocyte Surface Protein Band 3 and its Role in the Process of Oxygenation during CMV Infection in the Third Trimester of Pregnancy

Ion Exchange Properties of the Erythrocyte Surface Protein Band 3 and its Role in the Process of Oxygenation during CMV Infection in the Third Trimester of Pregnancy

According to the study, CMVI exacerbation in the third trimester of pregnancy increases the expression of the antigen on the surface of RBCs, which facilitates the penetration of toxic proteins tegument deep into the cells. This is followed by the launch of a cascade of hydrolytic and proteolytic processes, disturbing the protein-protein and lipid-protein interactions and leading to a redistribution in the ratio of proteins. The proof of this fact was the decreasing EBP3 content in RBC membranes of peripheral blood of CMV-seropositive pregnant women with CMVI exacerbation compared with the latent course of CMVI and CMV-seronegative pregnant women. These changes may be the result of possible conformational changes due to oxidative modiication, which breaks the association of EBP3 with ankyrin and the plasma membrane as a whole. [4] A disturbance in the structural integrity of EBP3
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Disturbance of oxidative balance in the first trimester of spontaneous abortions

Disturbance of oxidative balance in the first trimester of spontaneous abortions

In spontaneous abortions, the development of placental decidual basis is highly disrupted. Some studies show that the systemic and placental oxidative stress have a role in pathophysiological mechanism of spontaneous and recurrent miscarriage occurence 3 . The oxidants induce damage to the endothelium, damage to the placental vascularisation, immu- ne malfunctions, and have a major role in the pathophysiology of idiopathic recurrent miscarriages. In a physiological pregnancy the antioxidative mechanisms com- pensate for the intensified pro-oxidative processes. The spon- taneous abortion is coupled with a heavy disruption of the pro-oxidative-antioxidative homeostasis, ie the disruption of the antioxidative defense system. According to the literary data lipid peroxidation and antioxidative protection compo- nents are significantly changed during pregnancy as compa- red to the condition without pregnancy 4, 5 . Most of the aut- hors have established an increase in lipid peroxidation during pregnancy 6 . The study of Burton and Jauniaux 7 indicates an increase in lipid peroxidation intensity in the placenta as well as in the uterus of the pregnant woman.
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The studies of scale surface produced on outer diffusion layers

The studies of scale surface produced on outer diffusion layers

[9] S. Kobayashi, T. Yakou, Control of intermetallic compound layers at interface steel and aluminum by diffusion-treatment, Materials Science and Engineering, vol. A338 (2002) 44÷53. [10] K. Murakami, N. Nishida, K. Osamura , Y. Tomota, T. Suzuki, Aluminization of high purity iron and stainless steel by powder liquid coating, Acta Materialia vol. 52 (2004) 2173÷2184. [11] T. L. Hu, H. L. Huang, D. Gan, T. Y. Lee, The microstructure of aluminized type 310 stainless steel, Surface & Coatings Technology vol. 201 (2006) 3502-3509.

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The Relationship between Preeclampsia and Quadruple Screening Test in Nuliparous

The Relationship between Preeclampsia and Quadruple Screening Test in Nuliparous

19- Rachel K Morris, Jeltsje S Cnossen, Marloes Langejans, Stephen C Robson, Jos Kleijnen, Gerben ter Riet, Ben W Mol, Joris AM van der Post, and Khalid S Khan .Serum screening with Down's syndrome markers to predict pre-eclampsia and small for gestational age: Systematic review and meta-analysis .BMC Pregnancy Childbirth. 2008; 8: 33. Published online Aug 4, 2008. 20- Yaron Y, Cherry M, Kramer RL, O'Brien JE, Hallak M, Johnson MP, Evans MI. Second-trimester maternal serum marker screening: maternal serum alpha-fetoprotein, beta-human chorionic gonadotropin, estriol, and their various combinations as predictors of pregnancy outcome. Am J Obstet Gynecol. 1999;181:968–974.
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COMPARISION AND CORRELATION OF PAP SMEAR WITH COLPOSCOPY AND HISTOPATHIOLOGY IN EVALUATION OF CERVIX

COMPARISION AND CORRELATION OF PAP SMEAR WITH COLPOSCOPY AND HISTOPATHIOLOGY IN EVALUATION OF CERVIX

ABSTRACT: AIMS AND OBJECTIVES: Correlate pap smear findings with colposcopic findings, To localize the lesion by colposcopy and obtain biopsy and to provide appropriate treatment wherever possible. MATERIAL AND METHODS: This was a prospective comparative study of 104 patients who attended the Gynecology OPD of KIMS from may2012 to may2014. INCLUSION CRITERIA: 1. Women of age between 20-65 years. 2. Women with symptoms like vaginal discharge, post coital bleeding, postmenopausal bleeding, intermenstrual bleeding and persistent leucorrhoea. 3. Women with normal looking cervix but symptomatic. EXCLUSION CRITERIA: 1.Women with bleeding at the time of examination. 2. Women with frank lesions. 3. Women with clinical evidence of acute pelvic infection. 4. Women who was previously treated for carcinoma cervix. 5. Pregnant women. RESULTS: Sensitivity of pap smear was found to be very low which was 31.25% compared to its specificity which was 94.44%. Which means pap smear shows higher no. of false negative smears Colposcopy showed a high sensitivity 96.57% and a good specificity 88.55% compared to pap smear. CONCLUSIOS: It is evident that colposcopy is definitely more sensitive and accurate than pap smear. By combining pap smear with colposcopy, we can maximize the sensitivity and specificity of cancer cervix screening.
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UNIVERSIDADE FEDERAL DE UBERLÂNDIA FACULDADE DE MEDICINA PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE

UNIVERSIDADE FEDERAL DE UBERLÂNDIA FACULDADE DE MEDICINA PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE

The present study evaluated the association between duration and quality of sleep and the increase in the BMI during pregnancy. An effect of interaction between time of pregnancy and sleep quality was observed on the BMI. Further, it was found that pregnant women that maintained their BMI category “constant” during pregnancy increased their sleep time from the first to the third trimester, while those that ascend the BMI category slept the same time between these periods. These results indicate that a poor quality sleep over the pregnancy period as a whole, negatively impacts the weight gain distribution, and consequently the BMI. Such findings should be seen as worrying, due to the negative effects of inadequate weight gain on the outcome of pregnancy (Bodnar, 2009; Doherty, 2006; Fortner, 2009; Heslehurst, 2008; Stotland, 2004; Villamor, 2006). Such findings partially confirm our initial hypothesis - that the worse quality of sleep, but not the least duration -, is related to an inadequate pattern in the increase of BMI during pregnancy. This is found to be a relevant topic that is still under explored in the literature, and which reinforces the importance of standard follow-ups for sleep patterns in pregnant women in the search for adequate mother-fetus health.
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The Influence Of CSR Awareness On Consumer Purchase Decision Of A Telecommunication Network In Ghana A Case Of La Nkwantanag Madina Municipality

The Influence Of CSR Awareness On Consumer Purchase Decision Of A Telecommunication Network In Ghana A Case Of La Nkwantanag Madina Municipality

their purchasing behavior. The work on CSR and consumer choice could be a new growth opportunity for marketing. CSR initiatives with well-designed targets and high consumer awareness through communication could play an important role in successful marketing. Becker- Olsen et al. (2006) suspected the assumption that consumers will always reward firms for their socially responsible initiatives unselectively. They designed two studies to explore how consumers react to different CSR activities. In addition, they investigated the impact of the motivations and time choice of CSR initiatives. CSR activities that do not fit with a fir m‘s expertise have negative impact on consumers‘ attitudes toward a firm and the firm‘s credibility. Firms can be perceived as ―doing good‖ only by addressing selected CSR initiatives. CSR activities with low fitness with a firm are perceived as ―doing CSR business‖ by consumers, and lead to non-positive consumer evaluations. Perceived motivations of consumers have effect on consumers‘ evaluation of a firm and a firm‘s CSR initiatives. If consumers believe CSR initiatives are profit- driven rather than social-driven, then they will assess a firm and its credibility negatively. This leads to a low likelihood of consumers‘ purchase intention. The time of practicing CSR activities matters to consumers‘ assessments. Proactive CSR activities help firms get positive evaluations from consumers. In contrast, consumers regard reactive CSR activities as doing ―CSR business‖. Reactive CSR has non-positive contribution to a firm‘s image (Becker-Olsen et al., 2006).
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Seroprevalence of anti-rubella and anti-measles IgG antibodies in pregnant women in Shiraz, Southern Iran: outcomes of a nationwide measles-rubella mass vaccination campaign.

Seroprevalence of anti-rubella and anti-measles IgG antibodies in pregnant women in Shiraz, Southern Iran: outcomes of a nationwide measles-rubella mass vaccination campaign.

Measles during pregnancy may be severe and is linked to a higher incidence of pneumonitis, respiratory distress, stillbirth, spontane- ous abortion, hospitalization and death among pregnant women [4], [30–33]. The infants of pregnant women infected with measles have a higher incidence of prematurity, hospital admission and subacute sclerosing panencephalitis [4], [31–33]. Measles mortality has decreased in recent years because of higher vaccination coverage, and global measles deaths decreased by 78% from 2000 to 2008 [34]. In Iran, measles vaccination coverage between 1980 and 2005 ranged from 38% to 99%, with sustained high coverage (94% to 99% or higher) during the past decade [3]. However, in response to increased numbers of cases in older age groups during 1996–2002, a nationwide MR vaccination campaign was conducted in 2003 [8]. During 2004–2009, 221 laboratory-confirmed measles cases (,1 case per million population) were detected [8]. After the 2003 MR mass vaccination campaign, measles immunity in Iran reached 80.6% in the 6 to 10-year-old population, 72.7% in children aged 11 to 15 years, 84.9% in the 16 to 20-year-old age group and 87.5% in adults aged 20 to 26 years [11]. However, these levels of immunity for measles were significantly lower than the rates required to achieve 95% coverage or higher, the target required for elimination [11]. A survey in Urmia (northern Iran) showed that measles immunity in the population aged 5 to 25 years increased from 53% before to 72.3% after the 2003 mass vaccination campaign [35]. The present study showed that 81.7% of pregnant women were immune against measles, a figure similar to those in other countries. The rate of immunity among pregnant women was 88% in Iowa (USA) [24] and Argentina reported an 87.5% rate of measles seropositivity among women aged 15 to 49 years [27]. Other studies found immunity to measles in 79% of pregnant women in Germany [23], 80% to 90% of pregnant women in Japan [36] and 88.6% of women of childbearing age in Shanghai (China) [37].
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Selection of the temperature of casting the bronzes to plaster moulds

Selection of the temperature of casting the bronzes to plaster moulds

The opinion of the influence of the temperature of casting on the size of the volumetric contraction, the studied grades of the bronze, it was conducted on the basis of the size of contraction cavity on section along the axis of the probe TDAg. The opinion of processes setting on the surface of plaster mould and liquid bronze was conducted on station showed on Figure 4. Cylindrical samples were used to investigations, from the studied grades of the bronze, about dimensions Ø= 7 mm and h = 7 mm. The sam- ples were smelted in the stream of plasma, created among elec- trodes graphite and tungstic, in the protection of argon.
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The application of optical measurements for the determination of accuracy of gear wheels casts manufactured in the RT/RP process

The application of optical measurements for the determination of accuracy of gear wheels casts manufactured in the RT/RP process

The article discusses the possibilities of using optical measurements for defining the geometric accuracy of gear wheels casts manufactured in the rapid prototyping process. The tested gear wheel prototype was cast using an aluminum alloy. The casting mould was made by means of the three-dimensional print method (3DP) with the use of a Z510 Spectrum device. The aim of the tests was to determine the geometric accuracy of the cast made by the ZCast technology in the rapid prototyping process. The tests were conducted with the use of the coordinate optical measuring method and a GOM measuring device. The prototype measurements were made in the scanning mode. The results of the measurements, saved in the STL format with the use of the scanning device software, were compared with the gear wheel 3D-CAD nominal model. The measurements enabled the determination of the real accuracy of prototypes manufactured in casting moulds by means of the ZCast technology. The selection of the measuring method was also analyzed in terms of measurement accuracy and the RP technology precision.
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Einstein (São Paulo)  vol.14 número2

Einstein (São Paulo) vol.14 número2

Officially, the Brazilian Ministry of Health reinforces pregnant women to perform qualified prenatal test, and prescribed tests, and also they must report their physician any clinical changes, in addition to continue with preventive measures against Aedes aegypti (use of long sleeves, repellent, mosquito net, and elimination of standing water in and around home). Pregnant women should consult their physician before travel to risk areas. The Brazilian Ministry of Health recommends to health professionals careful evaluation of cephalic perimeter and gestational age during prenatal, and also notification of suspected cases of microcephaly at birth.
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Variação na disponibilidade de oxigênio e respostas antioxidantes no gastrópode Helix...

Variação na disponibilidade de oxigênio e respostas antioxidantes no gastrópode Helix...

Role of antioxidant defenses during estivation and anoxia exposure in fresh-water snails Biomphalaria tenagophila (Orbigny, 1835). The connection between oxidative stress [r]

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en 0102 6933 rgenf 36 spe 0055

en 0102 6933 rgenf 36 spe 0055

Objective: To investigate the association between hypertensive disorders and postpartum hemorrhage (PPH), by measuring the hemoglobin (Hb) and hematocrits (Ht) levels among women attending a university hospital in the Sao Paulo countryside. Method: Epidemiological, cross-sectional study, conducted with 100 primiparous, in the period between August and December 2012. Hemoglobin and hematocrit dosages were tested upon admission of the mother and 48 hours after delivery. Values ≥ 10% drop in the hematocrit numbers when compared to those shown in admission, were considered as HPP. HPP was considered the de- pendent variable and the independent variables were socioeconomic, pathological, prenatal care, admission, delivery and assistance. Univariate and bivariate statistics were used, with 5% significance level.
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Assessment Of Some Acceleration Schemes In The Solution Of Systems Of Linear Equations.

Assessment Of Some Acceleration Schemes In The Solution Of Systems Of Linear Equations.

Many practical problems can be reduced to systems of linear equations Ax = b, where A, b are known matrices and x is a vector of unknowns. Systems of linear equations play a prominent role in economics, engineering, physics, chemistry, computer science and other fields of Pure and Applied Sciences [2]. A solution to a system of linear equations is a set of numerical values ….. that satisfies all the equations in a system [1]. There are two classes of iterative methods [3]: linear stationary and linear nonstationary. The stationary iterative methods are the Jacobi, Gauss-Seidel and SOR and Nonstationary include Krylov subspace methods: Conjugate Gradient, Minimal Residual, Quasi-Minimal Residual, Generalizes Minimal Residual and Biconjugate gradient methods. The choice of a method for solving linear systems will often depend on the structure of the matrix A. According to [8] ideally, iterative methods should have the property that for any starting vector , it converges to a solution Ax = b. [5] is of the view that examination of the Jacobi iterative method shows that in general one must save all the components of the vector while computing the components of the vector for an iterative method. According to Hadjidimos [6], the first step in the construction of solution of stationary iterative methods usually begins with splitting of matrix A. Thus, A = M – N where det M and M is easily invertible so that A = b is equivalent to = T + C , where T = and C = giving the iterative scheme = T + C , (k = 0,1,2……). [2] noted that for systems of linear equation A the splitting matrix may be chosen in a different way; that is, one can split matrix A as A = D L U where D is the diagonal matrix, L and U are strictly lower and strictly upper triangular matrices respectively. In solving the systems of linear equations Ax = b, therefore, we consider any convergent method which produces a sequence of iterates { [7] .Quite often the convergence is too slow and it has to be accelerated. According to [9] to improve the convergence rate of the basic iterative methods, one may transform the original system A = b into the preconditioned form PA = Pb, where � is called the preconditioned or a preconditioning matrix. Convergent numerical sequences occur quite often in natural Science and Engineering. Some of such sequences converge very slowly and their limits are not available without suitable convergent acceleration method. Some known acceleration schemes are: Chebyshev Extrapolation scheme [4] and residual Smoothing.
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The Impact of E-Commerce Securi ty, and National Environment  on Consumer adoption of Intern et Banking in Malaysia and  Singapore

The Impact of E-Commerce Securi ty, and National Environment on Consumer adoption of Intern et Banking in Malaysia and Singapore

views an innovation as offering an advantage over previous ways of performing the same task (Roger, 1983; Agarwal & Prasad, 1997). Internet experience and banking need is defined as the degree to which an innovation is viewed as being consistent with the existing values, needs and experiences of a user (Rogers, 1983; Taylor & Todd, 1995). Trialability is the extent to which users would like an opportunity to experiment with an innovation prior to committing to its usage (Roger, 1983; Agarwal & Prasad, 1997). Subjective norm refers to a person’s perception that most people who are important to him or her think he or she should or should not perform the behavior in question (Fishbein & Ajzen, 1975; Tan & Teo, 2000). Self-efficacy is defined as an individual’s self-confidence in his or her ability to perform a behavior (Bandura, 1982; Taylor & Todd, 1995). While, facilitating condition refers to the easy access of technological resources and infrastructure. Government support is consistent with the national systems of innovation theory that posits that government policies may encourage or mandate technology development and adoption (King et. al., 1994; Wolcott et. al., 2001).
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Oxidative stress and bivalves: a proteomic approach

Oxidative stress and bivalves: a proteomic approach

2DE consists of sequential separation of proteins based first on isoelectric focusing (IEF) followed by orthogonal SDS PAGE (O’Farrell, 1975). Originally, a stable pH gradient was established in a polyacrylamide gel by including local buffering agents (ampholytes) when casting the gel. Proteins would migrate along the pH gradient until arriving at their isoelectric point (pI, the pH at which the protein has no net charge) and then stop moving. In this way proteins focus at their pI and the protein population separates in the rod gel into specific bands. In practice, it was technically demanding to achieve reproducible pH gradients in this system and there was a tendency for the entire gradient itself to migrate towards the cathode (“cathodic drift”; Lognonne, 1994). Immobilized pH gradients (IPGs) were later developed in which ampholytes were covalently immobilized along plastic strips (Görg et al., 2000). After IEF, the focused strip is exposed to SDS PAGE sample buffer, laid across the top of an SDS PAGE gel and electrophoresed. When stained with coomassie or silver stain (Rabilloud, 1992), individual proteins become visible as spots which are usually sharply- defined (Fig. 2). Since few proteins have identical pI and relative molecular mass (Mr), especially high- resolution separations are achievable in which pairs of samples (e.g., test and control) can be compared. By increasing the size of the gel, up to thousands of spots may be evident but, even in the smallest gels, several hundred spots may be resolved. Separations are captured and analyzed by image analysis software (Corzett et al., 2006). Independent labeling of lysines in test and control proteomes with up to three different fluorescent labels followed by their mixing and separation on a single gel allows comparison of tests and control samples without gel-to-gel variation, a technique called difference gel electrophoresis (DIGE) (Gade et al., 2003). For the purposes of the present review, it should be noted that 2DE separations can also be interrogated to identify proteins targeted by specific redox lesions, thus revealing redox-related differences not detectable by PES alone (Sheehan, 2006).
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Identification of boundary heat flux on the continuous casting surface

Identification of boundary heat flux on the continuous casting surface

In the paper the numerical solution of the inverse problem consisting in the identification of the heat flux on the continuous casting surface is presented. The additional information results from the measured surface or interior temperature histories. In particular the sequential function specification method using future time steps is applied. On the stage of numerical computations the 1st scheme of the boundary element method for parabolic equations is used. Because the problem is strongly non-linear the additional procedure 'linearizing' the task discussed is introduced. This procedure is called the artificial heat source method. In the final part of the paper the examples of computations are shown.
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Rev. esc. enferm. USP  vol.47 número6

Rev. esc. enferm. USP vol.47 número6

During gynecological consultaion, an efecive commu- nicaion (including on invesigaion of risk situaions, fear, and expectaions of pregnant women) must be associated with the appropriate physical examinaion and the use of speciic diagnosic technologies. Measurement of vaginal pH is among these technologies, and is part of the standard assessment of women complaining of vaginal symptoms. However, this study showed a high number of false posiive and false negaive results with relaively high sensiivity (71.4%) but low speciicity (44.4%). Thus, measurement of vaginal pH did not show a strong predicive power of vaginal infecion.
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The influence of the arc plasma treatment on the structure and microhardness C120U carbon tool steel

The influence of the arc plasma treatment on the structure and microhardness C120U carbon tool steel

The material used in this study was C120U steel. Chemical composition of this steel is presented in Table 1. Specimens as cuboids about dimensions 7,5 x 30 x 30 mm were conventional hardened (temperature austenitization – 770 o C, quenching in oil) and tempered (in temperature 250 o C). Temperatures hardening and tempering were chosen on the basis EN ISO 4957:1999 norms to obtain a structure with a relatively high toughness. Remelting surface was carried out using gas tungsten arc welding method. The surface of the samples were remelted by means of
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