[PDF] Top 20 Selection of specific colon cancer tumor peptides from combinatorial phage display libraries
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Selection of specific colon cancer tumor peptides from combinatorial phage display libraries
... O cancro colorectal, localizado no intestino grosso e no recto, é o terceiro cancro mais diagnosticado e a segunda causa de morte relacionada com doenças oncológicas. O cancro colorectal é uma doença muito heterogénea a ... See full document
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Identification of human embryonic progenitor cell targeting peptides using phage display.
... Phage display is a powerful ligand selection method that has been applied both in vitro and in vivo for the identification of cell- specific targeting peptides ...Peptide ... See full document
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Isolation of Osteosarcoma-Associated Human Antibodies from a Combinatorial Fab Phage Display Library
... peptide libraries [18, ...rounds of selection, and the reactivity analysis of the second and third rounds revealed that after two rounds we were able to identify Fabs that bind to osteosarcoma ... See full document
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Antibody phage display libraries : contributions to oncology
... identification of Ags by recombinant cDNA expression cloning (SEREX) method was designed to exploit patient serum to probe a tumor specific cDNA expression library with autologous patient serum ... See full document
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UNIVERSIDADE FEDERAL DE UBERLÂNDIA INSTITUTO DE GENÉTICA E BIOQUÍMICA PÓS-GRADUAÇÃO EM GENÉTICA E BIOQUÍMICA Instabilidadde cromossômica e alterações na expressão da telomerase durante a carcinogênese
... diagnosis of cancer are major goals of many research centers around the ...the phage display subtractive proteomic technology has provided important information for putative therapeutic ... See full document
160
Screening of a specific peptide binding to VPAC1 receptor from a phage display peptide library.
... detection of new CRC lesions or changes in the size of a known lesion caused by cancer growth are computed tomography (CT) and magnetic resonance imaging (MRI) ...detection of CRC is limited ... See full document
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Research Article Immunodiagnosis of Canine Visceral Leishmaniasis Using Mimotope Peptides Selected from Phage Displayed Combinatorial Libraries
... serodiagnosis of canine visceral leishmaniasis (CVL). The accuracy of these tests is controversial in endemic areas where canine infections by Trypanosoma cruzi may ...usefulness of synthetic ... See full document
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Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro
... requiring specific parasite and host cell molecules. The large amount of possible involved molecules poses additional difficulties for their identification by the classical biochemical ...construction ... See full document
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IDENTIFICAÇÃO DE PEPTÍDEOS LIGANTES AO VENENO DE Dinoponera australis (Hymenoptera, Formicidae, Ponerinae) POR PHAGE DISPLAY
... found from Mato Grosso to Rio Grande do Sul, as well as in neighboring ...presence of venom glands that are responsible for the production of a toxin constituted in its majority by ...identification ... See full document
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Phage display technology - Applications and innovations
... technique phage libraries are injected intrave- nously into animals and then organs or tissues are collected and examined for phage bound to tissue-specific endothe- lial cell markers (Figure ... See full document
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UNIVERSIDADE FEDERAL DE SÃO CARLOS CAMPUS SÃO CARLOS PROGRAMA INTERINSTITUCIONAL DE PÓS-GRADUAÇÃO EM CIÊNCIAS FISIOLÓGICAS PIPGCF UFSCar – UNESP
... loss of intercellular contacts and disorganization of cellular ...inhibition of integrin-dependent activation of FAK, Src and Paxillin in HUVECs have been demonstrated by signaling experiments ... See full document
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Peptides of the Constant Region of Antibodies Display Fungicidal Activity
... models of systemic and vaginal candidiasis, displayed a therapeutic ...survival of almost half of the mice systemically infected with ...recovery from the kidneys of treated and control ... See full document
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The use of Fluorescence Resonance Energy Transfer (FRET) peptidesfor measurement of clinically important proteolytic enzymes
... ation of substrate specificity of the two active sites of ACE, defining the requirements for C-domain specificity (Bersanetti et ...contribution of our group was the development of a ... See full document
12
Image-guided Electro-assisted Drug Delivery: Comparison Between Two Types of Electrodes
... elucidating of the above-mentioned questions is the development of highly target-specific and image-guided drug-delivery systems (DDS) with drug-release control, based on nanotechnologies ... See full document
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Reduction of Orc6 expression sensitizes human colon cancer cells to 5-fluorouracil and cisplatin.
... roles of JNK1 were quite complex due to its due role in both apoptotic and survival signaling pathways ...activator of JNK) undergo cellular senescence and G2/M growth arrest, further support our finding ... See full document
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Caracterização de moléculas envolvidas no desenvolvimento de melanoma pela metodologia de Phage display
... A seleção de peptídeos pode ser feita de diversas formas com resultados finais significativamente distintos. Biopanning com moléculas imobilizadas em plástico ou partículas inertes é recomendado para anticorpos, uma vez ... See full document
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Phage display of the serpin alpha-1 proteinase inhibitor randomized at consecutive residues in the reactive centre loop and biopanned with or without thrombin.
... C-terminus of non-cleavable signal sequence domains from either the human asialoglycoprotein receptor or the human transferrin receptor, ranging from 66 – 95 amino acids ...T7Select phage ... See full document
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Functional phage display of leech-derived tryptase inhibitor (LDTI): construction of a library and selection of thrombin inhibitors
... pro¢le of the LDTI variants it was necessary to produce more material, but it was di¤cult to generate enough fusion phages with the system ...suppliers of the pCANTAB 5E system are favoring this ...levels ... See full document
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Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1beta-dependent stabilization of Snail in tumor cells.
... sensitize colon cancer cells to TRAIL induced apoptosis through repression of MCL1 and cIAP2 in bax deficient HCT116 cells ...modulation of c-myc, MCL-1 or cIAP1 or cIAP2 in our system, using ... See full document
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Prediction of molecular targets of cancer preventing flavonoid compounds using computational methods.
... mechanisms of action of these plant-derived compounds are now a major area of ...Thousands of phytochemicals have been isolated, and a large number of them have shown protective ... See full document
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