[PDF] Top 20 Sequence variation in the melanocortin-1 receptor(
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Sequence variation in the melanocortin-1 receptor(
... test the selective neutrality of protein coding ...with the dif- fering color phenotypes in sand lizards in the sequence re- gion of ...Despite the high diversity of sites ... See full document
7
Cloning and characterization of a P2X receptor expressed in the central nervous system of Lymnaea stagnalis.
... 444–1146 in the LymP2X sequence (GenBank ...fixed in 4% paraformaldehyde for 4 hours at 4 uC and dehydrated in 25%, 40%, 60%, and 70% ethanol (10 min each) before being processed ... See full document
12
Persistence of duplicated PAC(1) receptors in the teleost, Sparus auratus
... production in a dose dependent ...for the alterna- tive IP3 signalling pathway. One hypothesis for the apparent functional divergence and differential expres- sion of sea bream paralogue receptors ... See full document
16
A novel melanocortin-4 receptor mutation MC4R-P272L associated with severe obesity has increased propensity to be ubiquitinated in the ER in the face of correct folding.
... retained in the ER ...enzyme 1 [23], also improved cell surface expression of wt-MC4R and of the obesity-associated MC4R I316S variant ...[20]. The effects of PBA and UBE1-41 were ... See full document
7
Mutations in the melanocortin-1 receptor (MC1R) gene have no influence on the distinct patterns of melanic plumage found in the manakins of the genus Antilophia (Aves: Pipridae)
... The melanocortin-1 receptor gene is the most widely-used marker for the investigation of the genetic determination of melanic plumage ...of the MC1R gene and ... See full document
7
Cloning and sequencing of c-DNA encoding N-methyl-D-aspartate receptor subunit-1 in the hypothalamus of male sheep
... - The objective of the present study was to report the molecular cloning and determination of the sequences N-methyl-D-aspartate subunit-1 receptor (NMDAR-1) in ... See full document
5
Understanding gene sequence variation in the context of transcription regulation in yeast.
... Among the genes residing within the linkage interval, the putative causal regulators (Table 1) were identified based on three criteria: (i) genes sharing the same biological process as ... See full document
9
The use of high-throughput DNA sequencing in the investigation of antigenic variation: application to Neisseria species.
... Antigenic variation occurs in a broad range of ...conversion in that variant DNA is unidirectionally transferred from partial gene copies (or silent loci) into an expression ...antigenic ... See full document
9
Rarity of DNA sequence alterations in the promoter region of the human androgen receptor gene
... androgen receptor (AR) gene promoter lies in a GC-rich region containing two principal sites of transcription initiation and a putative Sp1 protein-binding site, without typical “TATA” and “CAAT” ...within ... See full document
6
Minimizing Assembly Errors by Selecting Optimum Assembly Sequence in the Assembly of a Rigid Circular Structure
... proposed in this paper to minimize error accumulation in the assembly of fabricated ...together in order to maintain symmetric distance between all parts and the axis around which ... See full document
12
Copy number variation and Huntington’s disease
... Variation in the human genome encompasses single-nucleotide polymorphisms (SNPs), small insertion-deletion (indel) polymorphisms, variable numbers of repetitive sequences, and genomic structural ... See full document
215
en 1806 3446 ptp 32 spe e32ne22
... S2 in blocks of 10 trials in the Training, Elimination and Testing phases for each participant of each group is shown in Figure ...3. In the Training Phase all participants ... See full document
12
EFFECTS OF MELANOCORTIN-4 RECEPTOR GENE ON GROWTH AND MEAT TRAITS IN PIGS RAISED IN RUSSIA
... of the MC4R genotypes in LC breed were observed only for male LC. The difference of ...that the ADG and FI better in genotype GG (LC male) compared with genotypes AA and AG, but these ... See full document
6
Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation.
... design in which each basal epidermal sample was hybridized together with a common RNA reference ...design. The cDNA microarrays used in this study were generated at Stanford University, Stanford ... See full document
14
Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor
... firmed the microarray data by RT-PCR on a subset of genes down-regulated by WT-Mc1r ...examined the down-regulation of sulfiredoxin 1 (Srxn1), which exhibited the largest reduction in ... See full document
6
Effects of melanocortin 1 receptor agonists in experimental nephropathies.
... into the tail vein, 1.5 ml at day 0 and 0.5 ml at day 7. Instead of the PHN-inducing antibody, controls received sterile ...subcutaneously in the neck or via subcutaneous injections. ... See full document
7
Linkage disequilibrium in wild mice.
... of the underlying causative genes have been identified. The main difficulty is the extensive linkage disequilibrium (LD) in intercross progeny and the slow process of fine-scale mapping ... See full document
9
Electronic Government In Democratic Public Service In One Door Integrated Permit Handling Services Agency In The City Of Samarinda
... communication in a public sector have to pay more attention to the complexity in its implementation rather than focusing on best practice and strategies which are universal to prescribe how ... See full document
6
TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.
... out in collaboration with the TaconicArtemis GmbH (Ko¨ln, ...of the Trem1 gene and to allow for a possible cell-specific ablation of Trem1 expression, a targeting vector was designed for conditional ... See full document
17
The heterodimeric glycoprotein hormone, GPA2/GPB5, regulates ion transport across the hindgut of the adult mosquito, Aedes aegypti.
... is the glycoprotein cysteine knot-forming heterodimers consisting of alpha- (GPA) and beta-subunits (GPB), which assemble by noncovalent ...bonds. In mammals, a common glycoprotein hormone alpha- subunit ... See full document
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