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[PDF] Top 20 Small-molecule boron compounds to use against interleukin-23

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Small-molecule boron compounds to use against interleukin-23

Small-molecule boron compounds to use against interleukin-23

... - Compounds with and without the pyridine ring in their ...structure. Compounds are grouped being the first one the structure containing the phenyl ring and the second one the structure containing the ... See full document

32

In vitro and in vivo activity of a novel antifungal small molecule against Candida infections.

In vitro and in vivo activity of a novel antifungal small molecule against Candida infections.

... a small molecule with activity against Candida ...50,240 small molecules for inhibitors of yeast-to-hypha transition, a major virulence attribute of Candida ...these compounds, ... See full document

17

Global analysis of small molecule binding to related protein targets.

Global analysis of small molecule binding to related protein targets.

... of small molecule binding across species As a first step to estimate the robustness of small molecule binding globally, we compared bioactivity data for compounds that have been ... See full document

9

Discovery and computer aided potency optimization of a novel class of small molecule CXCR4 antagonists.

Discovery and computer aided potency optimization of a novel class of small molecule CXCR4 antagonists.

... of small molecule CXCR4 antagonists based on the use of computational modelling studies in concert with experimental determination of in vitro activity against CXCL12-induced intracellular ... See full document

18

Photochemical aging of volatile organic compounds associated with oil and natural gas extraction in the Uintah Basin, UT, during a wintertime ozone formation event

Photochemical aging of volatile organic compounds associated with oil and natural gas extraction in the Uintah Basin, UT, during a wintertime ozone formation event

... these compounds contain a carbonyl functional group, and photolysis rates could be ...proportional to solar actinic flux and scaled to photolysis constants from the literature (values and litera- ... See full document

15

BORON NUTRITION AND YIELD OF ALFALFA CULTIVAR CRIOULA IN RELATION TO BORON SUPPLY

BORON NUTRITION AND YIELD OF ALFALFA CULTIVAR CRIOULA IN RELATION TO BORON SUPPLY

... was to determine: I. the boron acquisition by this alfalfa cul- tivar; ...the boron need for improving alfalfa production; III. the boron distribution in the plants; ...of boron ... See full document

5

ALTERNATIVE BINDERS TO BENTONITE FOR IRON ORE PELLETIZING : PART II : EFFECTS ON METALLURGICAL AND CHEMICAL PROPERTIES

ALTERNATIVE BINDERS TO BENTONITE FOR IRON ORE PELLETIZING : PART II : EFFECTS ON METALLURGICAL AND CHEMICAL PROPERTIES

... silica to the finished product ...is to remove silicate minerals from the ore, adding silicates back in the form of binder is ...binders to bentonite have been tested for many ... See full document

8

J. Braz. Chem. Soc.  vol.22 número9

J. Braz. Chem. Soc. vol.22 número9

... responsive to radiation therapy and is rather treated by surgically, for example by pneumonectomy or ...Thus small molecules that are active against human lung adenocarcinoma cell line may be useful ... See full document

13

Discovery of novel small molecule activators of β-catenin signaling.

Discovery of novel small molecule activators of β-catenin signaling.

... subjected to western blotting for b-catenin and ...relative to the expression of the housekeeping gene TATA box-binding protein (TAFII) by means of ... See full document

7

Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance.

Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance.

... directly to the RS domain of SR proteins and thereby impede its phosphorylation, at least in vitro, by SR kinases ...synergistically to modify HIV-1 RNA splicing and/or ...have to determine whether ... See full document

10

Mat. Res.  vol.16 número4

Mat. Res. vol.16 número4

... Thin film technique was used to identify the precipitates and precipitation sites and to analyze the steel matrices. The thin films were obtained by machining billet shapes with 3 mm diameter and 0.20 mm ... See full document

8

Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media.

Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media.

... order to derivate hMSCs from hNCCs, the culture medium was changed from that for hNCC to aMEM with 10% FBS (Figure 7A), which we used previously for human bone marrow-derived MSCs (hBM-MSCs) ...comparable ... See full document

25

A convenient synthesis and cytotoxic activity of 3aryl5pentyl1,2,4oxadiazoles from carboxylic acid esters and  under solventfree conditions

A convenient synthesis and cytotoxic activity of 3aryl5pentyl1,2,4oxadiazoles from carboxylic acid esters and under solventfree conditions

... The compounds 3a-f were tested against three human cell lines where only of compounds 3c, 3e and 3f exhibited moderate antiproliferative activity against HL-60 cancer cell lines with IC 50 ... See full document

4

Small molecule inhibitors target the tissue transglutaminase and fibronectin interaction.

Small molecule inhibitors target the tissue transglutaminase and fibronectin interaction.

... Figure 5. Effect of TG53 on SKOV3 cell migration, invasion, and proliferation. A, Representative phase-contrast microscopy images of cells migrating into the wounded area in an in vitro scratch wound healing assay. SKOV3 ... See full document

10

Matéria (Rio J.)  vol.22 número2

Matéria (Rio J.) vol.22 número2

... So far, the higher ionic conductivity, amounting ~ 18 mS.cm -1 at 600ºC, was found for the system zir- conia-10 mol% scandia-1 mol% ceria [10]. However, it was found that the cubic phase transforms on the surface of the ... See full document

7

Rev. bras. farmacogn.  vol.25 número4

Rev. bras. farmacogn. vol.25 número4

... Sidastrum paniculatum (L.) Fryxell, Malvaceae, is popularly known in Brazil as “malva roxa” or “malvavisco”. The species is wide spread in Northeast region, especially in Paraiba and Pernambuco states (Baracho, 1995). ... See full document

6

Effects of the small molecule HERG activator NS1643 on Kv11.3 channels.

Effects of the small molecule HERG activator NS1643 on Kv11.3 channels.

... suited to investigate Kv11.3 channel inactivation due to its faster deactivation kinetics limiting the maximal fraction of open channels achieved upon re- or hyperpolarizing ...used to directly ... See full document

11

ALTERNATIVE BINDERS TO BENTONITE FOR IRON ORE PELLETIZING: PART I: EFFECTS ON PHYSICAL AND MECHANICAL PROPERTIES

ALTERNATIVE BINDERS TO BENTONITE FOR IRON ORE PELLETIZING: PART I: EFFECTS ON PHYSICAL AND MECHANICAL PROPERTIES

... facilities to produce metallic iron are not abundant in earth’s crust to supply the increasing consumption of iron-steel ...S compounds have to be upgraded to an acceptable sufficient ... See full document

10

Caenorhabditis elegans as a model to screen plant extracts and compounds as natural anthelmintics for veterinary use

Caenorhabditis elegans as a model to screen plant extracts and compounds as natural anthelmintics for veterinary use

... in small ruminant production due to high morbidity and high mortality caused by ...test to determine if a com- pound has anthelmintic activity for veterinary use would be to use ... See full document

5

Braz. J. Pharm. Sci.  vol.53 número1

Braz. J. Pharm. Sci. vol.53 número1

... and to make a two-fold dilution of the tested ...added to tube #10 as a sterility control for ...order to maintain the viable cell ...according to the guidelines of the European Committee for ... See full document

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