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[PDF] Top 20 Splenectomy does not interfere with immune response to Leishmania major infection in mice

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Splenectomy does not interfere with immune response to Leishmania major infection in mice

Splenectomy does not interfere with immune response to Leishmania major infection in mice

... L. major, the most studied Leishmania, infection resis- tance is correlated with Th1 type response characterized by IL-12 produced by dendritic cells and macrophages IFN-gamma and ... See full document

7

Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.

Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.

... exposure to the parasite, become silenced when the infection is firmly established, rendering the cell unresponsive to further stimulation with LPS ...attributed to different virulence ... See full document

15

Behavior of Leishmania major metacyclic promastigotes during the course of infection and immune response development in resistant versus susceptible hosts

Behavior of Leishmania major metacyclic promastigotes during the course of infection and immune response development in resistant versus susceptible hosts

... used to infect groups of inbred mice, well-known for their susceptibility or resistance to ...L. major. Their pattern of lesion development, as well as the in vivo cellular ... See full document

4

SUBCUTANEOUS IMMUNIZATION AGAINST Leishmania major - INFECTION IN MICE: EFFICACY OF FORMALIN-KILLED PROMASTIGOTES COMBINED WITH ADJUVANTS

SUBCUTANEOUS IMMUNIZATION AGAINST Leishmania major - INFECTION IN MICE: EFFICACY OF FORMALIN-KILLED PROMASTIGOTES COMBINED WITH ADJUVANTS

... a major health problem, due to inefficiency of available control ...measures. To date, there is no vaccine against any form of leishmaniasis for general human use (KHAMESIPOUR et ...chemotherapy ... See full document

6

The influence of ecto-nucleotidases on Leishmania amazonensis infection and immune response in C57B6 mice

The influence of ecto-nucleotidases on Leishmania amazonensis infection and immune response in C57B6 mice

... of Leishmania parasites in culture decreases the infectivity of the ...culture. To avoid loss of infectivity parasite strains are regularly re-isolated from infected hamsters or ...mice. ... See full document

8

Immune modulating effects of NKT cells in a physiologically low dose Leishmania major infection model after αGalCer analog PBS57 stimulation.

Immune modulating effects of NKT cells in a physiologically low dose Leishmania major infection model after αGalCer analog PBS57 stimulation.

... contrast to resistant C57BL/6 mice, susceptible BALB/c mice routinely develop a Th2/Th17 response to ...L. major not allowing them to contain the parasite and ... See full document

11

MC de Almeida+ , V Vilhena, A Barral, M Barral-Netto

MC de Almeida+ , V Vilhena, A Barral, M Barral-Netto

... response to L. major infection (von Stebut et ...emphasis in searching peptides that, recognized by the adaptative immune system, will direct the immune response ... See full document

10

MAJOR-INFECTION IN MICE BY NORMAL POLYSPECIFIC

MAJOR-INFECTION IN MICE BY NORMAL POLYSPECIFIC

... believed to play a key role in controlling the intracellular pathogens but can also trigger inflammatory complications of many infectious ...implicated in the development of tissue damage in ... See full document

34

Experimental infection of Leishmania chagasi in immunosuppressed balb/c mice: cellular immune response and parasite burden

Experimental infection of Leishmania chagasi in immunosuppressed balb/c mice: cellular immune response and parasite burden

... The immune response to leishmaniasis can result in a polarization of a subpopulation of T lymphocytes, which leads to a different cell phenotype and results in immune ... See full document

1

Resolution of an Infection with Leishmania braziliensis Confers Complete Protection to a Subsequent Challenge with Leishmania major in BALBc Mice

Resolution of an Infection with Leishmania braziliensis Confers Complete Protection to a Subsequent Challenge with Leishmania major in BALBc Mice

... genus Leishmania induce a spectrum of diseases in humans and in experimen- tal ...animals. Infection of mice with L. major, one cause of cutaneous leishmaniasis, is ... See full document

6

Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.

Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.

... of infection are identified, and the different diseases have wide-ranging symptoms from localized cutaneous sores to visceral disease affecting many internal ...established in which disease is ... See full document

11

Purinergic signaling and infection by Leishmania: A new approach to evasion of the immune response

Purinergic signaling and infection by Leishmania: A new approach to evasion of the immune response

... host to control para- site growth, several mechanisms contribute to evasion of the immune response by ...include, in addition to those already mentioned above, escape from ... See full document

7

ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION

ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION

... reported to occur during active visceral leishmaniasis and some factors such as the cytokine profile may be involved in this ...process. In the mouse model of cutaneous leishmaniasis using ... See full document

6

T-cell responses associated with resistance to Leishmania infection in individuals from endemic areas for Leishmania (Viannia) braziliensis

T-cell responses associated with resistance to Leishmania infection in individuals from endemic areas for Leishmania (Viannia) braziliensis

... (L.) major infection, but only one requires the presence of the parasite (Wherry et ...2005). In humans, it is difficult to determine whether or not long life immunity is depen- dent on ... See full document

6

Involvement of the Chemokine RANTES (CCL5) in Resistance to Experimental Infection with Leishmania major

Involvement of the Chemokine RANTES (CCL5) in Resistance to Experimental Infection with Leishmania major

... Resistance to leishmaniasis is highly dependent on a Th1 response ...ment with Met-RANTES or anti-CCL5 rendered C57BL/6 an- imals more susceptible to ...L. major and skewed the ... See full document

6

Low and high-dose intradermal infection with Leishmania major and Leishmania amazonensis in C57BL6 mice

Low and high-dose intradermal infection with Leishmania major and Leishmania amazonensis in C57BL6 mice

... infected mice. The low IFN-γ production is, in our experience, at least partially responsible for the mainte- nance of parasites in ...shown to favor growth of L. amazonensis amastigotes ... See full document

10

Cell-mediated immune response to Leishmania chagasi experimental infection of BALB/c immunosuppressed mice

Cell-mediated immune response to Leishmania chagasi experimental infection of BALB/c immunosuppressed mice

... lower in the immunosuppressed group than in the control and uninfected groups at the end of immunosuppressive treatment suggests that immunosuppression caused by dexamethasone until day 0 was reversible ... See full document

16

Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response.

Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response.

... humanized mice and BALB/c mice with Miltefosine. In BALB/c mice the application of Miltefosine induced a reduction of the parasite load predominantly in visceral organs such as ... See full document

12

Early infection with Leishmania major restrains pathogenic response to Leishmania amazonensis and parasite growth

Early infection with Leishmania major restrains pathogenic response to Leishmania amazonensis and parasite growth

... L. major pre-infected mice in weeks 6 and 10 after infection with ...mRNA in lesions were not different between pre-infected mice and their ...pre-infection ... See full document

12

Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALBc mice

Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALBc mice

... obtained in other studies have shown de- creased diet consumption when a hypoproteic diet is used (Chatraw et ...reduction in the levels of total protein, al- bumin and globulins in the mice ... See full document

7

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