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[PDF] Top 20 Toward a systems-level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria

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Toward a systems-level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria

Toward a systems-level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria

... early in 2005 (Shastri and Morgan, 2005) and only included the evaluation of central metabolic pathways, under different light and media conditions ...mixotrophic, and ... See full document

18

GRNsight: a web application and service for visualizing models of small- to medium-scale gene regulatory networks

GRNsight: a web application and service for visualizing models of small- to medium-scale gene regulatory networks

... trends, and usage of visualization tools available for genomics and systems ...list of 47 tools for network analysis is representative of what was available to us at our project ... See full document

24

Inference of gene regulatory networks with sparse structural equation models exploiting genetic perturbations.

Inference of gene regulatory networks with sparse structural equation models exploiting genetic perturbations.

... Genes in living organisms do not function in isolation, but may interact with each other and act together forming intricate networks ...structure of gene regulatory ... See full document

13

Changes in protein interaction networks between normal and cancer conditions: Total chaos or ordered disorder?

Changes in protein interaction networks between normal and cancer conditions: Total chaos or ordered disorder?

... static networks, but dynamic network based studies are needed to bring out more realistic ...interpretations. Protein interaction network with association of gene regulatory ... See full document

14

Molecular monitoring of cyanobacteria and their related toxins in Portuguese freshwater systems

Molecular monitoring of cyanobacteria and their related toxins in Portuguese freshwater systems

... presence of C. raciborskii in Portuguese freshwater systems was the least frequent of the three cyanobacterium species in ...2 of Parque da Cidade do Porto, with a punctual ... See full document

77

Metabolic networks in aging and age-related diseases

Metabolic networks in aging and age-related diseases

... regulator of autophagy in cancer stem cells (CSC) and also a main determinant of its level of pluripotency ...positive and negative regulatory role at the same time ... See full document

106

Interaction between plate make and protein in protein crystallisation screening.

Interaction between plate make and protein in protein crystallisation screening.

... each protein: the precipitant at the published crystallisation concentration, the precipitant at a concentration 20% lower than the published condition and the precipitant at a concentration 20% higher than ... See full document

5

Toward Understanding Prevalence of Airborne Microorganisms in a Hot-Arid Environment

Toward Understanding Prevalence of Airborne Microorganisms in a Hot-Arid Environment

... 1994) and microbial particle size determines its behavior (deposition/dispersion) in the atmosphere (Nicholson, ...conditions and periodicity of sources may inluence composition, abundance, ... See full document

11

Exploring overlapping functional units with various structure in protein interaction networks.

Exploring overlapping functional units with various structure in protein interaction networks.

... units in PPI networks resort to identifying cohesive protein complexes or functional modules [2–4] (Here, we do not distinguish protein complexes from functional modules because the underlying ... See full document

11

Understanding the undelaying mechanism of HA-subtyping in the level of physic-chemical characteristics of protein.

Understanding the undelaying mechanism of HA-subtyping in the level of physic-chemical characteristics of protein.

... apply in such conditions. The performances of Naı¨ve Bayes models (with and without kernel) were also high enough (more than 99%), which also makes these models to cluster HA subtypes into the right ... See full document

14

Interaction of West-Nile virus capsid protein with lipid systems

Interaction of West-Nile virus capsid protein with lipid systems

... VLDL and LDL were isolated from human plasma by ...VLDL and LDL were ultrafiltered through a membrane and packaged aseptically under nitrogen (purity ...provided in a solution with 154 mM ... See full document

86

Genome-wide identification of regulatory elements and reconstruction of gene regulatory networks of the green alga Chlamydomonas reinhardtii under carbon deprivation.

Genome-wide identification of regulatory elements and reconstruction of gene regulatory networks of the green alga Chlamydomonas reinhardtii under carbon deprivation.

... identification of nucleosome-depleted regions and putative regulatory elements of ...present in the FAIRE samples were sequenced by deep sequencing ...plants and no protocol was ... See full document

16

Understanding dengue virus capsid protein interaction with key biological targets

Understanding dengue virus capsid protein interaction with key biological targets

... hospitalizations and 20,000 deaths worldwide every year 1–4 ...toll in 390 million people infected per year 5 , roughly three times higher than earlier projections 1,3,4,6 ...fever and the often ... See full document

13

Inference of cross-level interaction between genes and contextual factors in a matched case-control metabolic syndrome study: a Bayesian approach.

Inference of cross-level interaction between genes and contextual factors in a matched case-control metabolic syndrome study: a Bayesian approach.

... study of metabolic syndrome [16], a condition which is characterized by a group of metabolic conditions and risk ...factors. In that metabolic disorder study, the effects ... See full document

7

Protected fat and variable level of protein

Protected fat and variable level of protein

... difference in treatments (p > 0.05) on milk production and composition (Table 6), corroborating results in DM consumption (Table 4) and TDN of diets (Table ...results in ... See full document

6

Analysis and prediction of the metabolic stability of proteins based on their sequential features, subcellular locations and interaction networks.

Analysis and prediction of the metabolic stability of proteins based on their sequential features, subcellular locations and interaction networks.

... that protein stability was correlated with amino acid ...group and medium half-life group had a larger proportion of the unstable ‘‘cell cycle control’’ proteins, and that the long half-life ... See full document

9

Global systems-level analysis of Hfq and SmpB deletion mutants in Salmonella: implications for virulence and global protein translation.

Global systems-level analysis of Hfq and SmpB deletion mutants in Salmonella: implications for virulence and global protein translation.

... mass and elution time (AMT) tag approach ...mass and the observed normalized elution time (NET) of each peptide identified by LC-MS/MS is used to construct a reference database of AMT tags, ... See full document

13

Attractor metabolic networks.

Attractor metabolic networks.

... behavior in the dissipative metabolic network (DMN). A,D: metabolic network formed by 18 self-organized multienzymatic complexes (metabolic subsystems); it is shown the interconnection by ... See full document

20

Influence of the experimental design of gene expression studies on the inference of gene regulatory networks: environmental factors

Influence of the experimental design of gene expression studies on the inference of gene regulatory networks: environmental factors

... interventional gene expression data (normal environmental condition interrupted by a positive spike-in stimulation) and the subnetwork of the transcriptional regulatory network ... See full document

20

Toward an understanding of youth in community governance: Policy priorities and research directions

Toward an understanding of youth in community governance: Policy priorities and research directions

... much of the general public, including parents, does not perceive youth as having the values, motivation, or competence to contribute to civic life (Bostrom, 2000; Offer & Schonert-Reichl, 1992; Zeldin, ... See full document

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