[PDF] Top 20 Target inhibition of IL1 receptor prevents ifosfamide induced hemorrhagic cystitis in mice
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Target inhibition of IL1 receptor prevents ifosfamide induced hemorrhagic cystitis in mice
... form of naturally occurring IL-1Ra that acts as a specific blocker of IL-1 ...tested in rheumatoid arthritis. 13 We hypothesized that blockade of IL-1R by anakinra could attenuate ...mediator ... See full document
10
Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.
... lines of evidence indicated that LPS/TLR4 signaling provides a mechanistic link between inflammation and fibrosis, and plays an important role in liver fibrosis ...[27]. In addition, some in ... See full document
19
Extract of Kuding tea prevents high-fat diet-induced metabolic disorders in C57BL/6 mice via liver X receptor (LXR) β antagonism.
... Development of selective agonists or antagonists of LXRs may avoid the off-target effects ...the inhibition of LXR signaling ...transactivity in the presence of the LXRb ... See full document
12
Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.
... sample of post-natal full-term placenta was collected from St Olavs hospital (Trondheim, ...pieces of placenta were immediately placed in RNAlater and stored at ...use of anonymized biological ... See full document
17
Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner ear.
... exist in a finely tuned balance between survival and cell death ...operate in HCs have been defined, including the H-Ras/Raf/MEK/Erk pathway and the PI3K-Akt pathway ...toxicity in neonatal rat OC ... See full document
10
Differential neuroprotection by A(1) receptor activation and A(2A) receptor inhibition following pilocarpine-induced status epilepticus
... lines of inclusion and two of ...numbers of cells were summed to obtain the mean total number of FJ-B-positive cells sampled in each area of ...set of brain sections by an ... See full document
7
Reaction of hybrids, inhibition in vitro and target spot control in cucumber
... discs of the PESP01, PESP02, PESP04, PESP05, PESP06 and PEGO07 ...edges of the colonies when approximately 10 days old and transferred to the different culture media (with and without ...25°C in ... See full document
7
Anti-inflammatory and antinociceptive activities of an acid fraction of the seeds of Carpotroche brasiliensis (Raddi) (Flacourtiaceae)
... fraction of C. brasiliensis was obtained by maceration and extraction of the dried seeds ...addition of 150 ml water, the aqueous phase was acidified with 100 ml 10% (v/v) aqueous hydrochloric ... See full document
9
Lipid transfer protein isolated from noni seeds displays antibacterial activity in vitro and improves survival in lethal sepsis induced by CLP in mice
... activity of a lipid transfer protein isolated from Morinda citrifolia ...effect in the cecal ligation and puncture (CLP) mouse sepsis ...maximal inhibition of approximately 50% and 98%, ... See full document
9
Einstein (São Paulo) vol.11 número2
... Nitric oxide metabolites in the lumbosacral spinal cord interstice and cerebrospinal fluid in female.. rats with acute cyclophosphamide-induced cystitis[r] ... See full document
1
Diminazene aceturate, an angiotensinconting enzyme II activator, prevents gastric mucosal damage in mice : role of the angiotensinmas receptor axis
... process of healing involves a coordinated cascade of events that result in tissue ...independent of the agent that caused the ...tion. In the final phase, collagen plays a key role ... See full document
10
IKKε knockout prevents high fat diet induced arterial atherosclerosis and NF-κB signaling in mice.
... length of the aorta from mice of each group and separated by ...twice in Tris-buffered saline (TBS) with TweenH diluted 1:1000 (TBST; Promega, Madison, WI, USA), for 10 min each time, and ... See full document
9
Drug-induced regulation of target expression.
... profiles of 4 cell lines treated with 1309 distinct small ...performed in multiple steps as follows: Treatment instances ...treatments in HT_HG-U133A platform were selected (with the exception ... See full document
8
Int. braz j urol. vol.41 número6
... ments of hemorrhagic cystitis require the patient to be free of bladder clots, which can be achieved with aggressive manual irrigation or cystoscopy with clot evacuation and ...instillation ... See full document
6
Genetic deficiency in neprilysin or its pharmacological inhibition initiate excessive stress-induced alcohol consumption in mice.
... parts of the western society. In the US alone, 14 million people meet standard criteria for alcohol abuse or alcoholism [1], triggering massive expenses in health care (approximately $180 billion ... See full document
6
Identification of estrogen receptor-related receptor gamma as a direct transcriptional target of angiogenin.
... two of the fragments contained the same sequence upstream of ERRc ...expression in breast cancer ...development of prostate cancer [14] and breast cancer [15] in mouse ...expression ... See full document
9
Norepinephrine-Induced Adrenergic Activation Strikingly Increased the Atrial Fibrillation Duration through β1- and α1-Adrenergic Receptor-Mediated Signaling in Mice.
... involved in AF ...roles in the development of AF [8]. Consistently, activation of the sympathetic and parasympathetic systems is observed before the onset of AF ...[27]. In ... See full document
13
Einstein (São Paulo) vol.15 número4
... increase in the adipose tissue mass, and is associated with higher incidence of several chronic metabolic diseases, such as type 2 ...activation in adipose tissue of the mechanistic ... See full document
5
Nitric oxide paradox in asthma
... influx of eosinophils into the bronchoalveolar lavage (BAL) fluid and lung tis- sue of sensitized and OVA-challenged ...eosinophilia. In contrast, treatment with L-NIL, a selective NOS2 inhibitor, ... See full document
6
Adenosine A(2A) receptor agonist (CGS-21680) prevents endotoxin-induced effects on nucleotidase activities in mouse lymphocytes
... CGS-21680 hydrochloride (3-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5- (ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]purin-2-yl]amino]ethyl] phenyl]propanoic acid), HEPES (2-[4-(2-hydroxyethyl)piperazin-1-yl] ethanesulfonic acid), ... See full document
6
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