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[PDF] Top 20 The role of post-translational modifications on STAT3 interactions

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The role of post-translational modifications on STAT3 interactions

The role of post-translational modifications on STAT3 interactions

... DNA. The plasmid templates have been amplified in bacteria, where they were methylated, but the in vitro PCR generates a new double- stranded DNA molecule without ...digests the template DNA, in ... See full document

71

Post-translational modifications modulate ligand recognition by the third PDZ domain of the MAGUK protein PSD-95.

Post-translational modifications modulate ligand recognition by the third PDZ domain of the MAGUK protein PSD-95.

... in the a3 helix and Lys355 in the b4 strand, and between Arg399 in the a3 helix and Glu334 in the b2- b3 ...important role in KKETAV binding via interactions with Lys-5 in ... See full document

11

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

... to the pre-treated samples. The three sites in the region of interest, which are in the concentrated region of mutations found in Noonan and LEOPARD syndrome samples, follow ... See full document

14

Overlooked post-translational modifications of proteins in Plasmodium falciparum: N- and O-glycosylation - A review

Overlooked post-translational modifications of proteins in Plasmodium falciparum: N- and O-glycosylation - A review

... demonstrated the importance of glyco- sylated proteins in the immunogenicity of ...and the carbohydrate modification of the epitopes was confirmed by their in- sensitivity ... See full document

8

Novel Antimicrobial Peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the Edible Sea Urchin Echinus esculentus Have 6-Br-Trp Post-Translational Modifications.

Novel Antimicrobial Peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the Edible Sea Urchin Echinus esculentus Have 6-Br-Trp Post-Translational Modifications.

... problem of microbial resistance to antibiotics has resulted in an urgent need to develop new antimicrobial ...rely on innate immunity factors in the defence against harmful microorganisms, are ... See full document

25

Characterizing HSF1 Binding and Post-Translational Modifications of hsp70 Promoter in Cultured Cortical Neurons: Implications in the Heat-Shock Response.

Characterizing HSF1 Binding and Post-Translational Modifications of hsp70 Promoter in Cultured Cortical Neurons: Implications in the Heat-Shock Response.

... that the initial steps required for HSF1 activation are operative in ...test the transactiva- tion ability of HSF1 in neuronal cells, gene reporter assays were performed using ...Kb of ... See full document

16

Post-translational regulation of Oct4 transcriptional activity.

Post-translational regulation of Oct4 transcriptional activity.

... use of embryonic stem cells as therapeutics requires firm understanding of the mechanisms that control their proliferation and ...regulators of these ...as Stat3, Nanog, and Oct4 as ... See full document

9

Assigning quantitative function to post-translational modifications reveals multiple sites of phosphorylation that tune yeast pheromone signaling output.

Assigning quantitative function to post-translational modifications reveals multiple sites of phosphorylation that tune yeast pheromone signaling output.

... by post-translationally modifying signaling proteins, often via ...thousands of sites of phosphorylation have been identified in proteomic studies, the vast majority of sites have no ... See full document

11

The role of asymmetric interactions on the effect of habitat destruction in mutualistic networks.

The role of asymmetric interactions on the effect of habitat destruction in mutualistic networks.

... Besides the direct effect of erasing a fraction of plant and animal species, the disturbance has also an effect on the ...when the system settles in its new equilibrium, ... See full document

9

Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.

Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.

... loop of MscL is the least conserved part of the channel and probably the least ...digestion of the periplasmic loop, periplasmic and cytoplasmic extra membrane domains ... See full document

23

Discovery of novel biomarkers in gastric cancer based on post-translational modifications of glycoproteins

Discovery of novel biomarkers in gastric cancer based on post-translational modifications of glycoproteins

... is the primary tissue for plasminogen synthesis (Raum et ...including the gut, have been described in animal models (Zhang et al., 2002). The truncated O-glycans observed in circulating plasminogen ... See full document

266

Asymmetric post-translational modifications regulate the intracellular distribution of unstimulated STAT3 dimers

Asymmetric post-translational modifications regulate the intracellular distribution of unstimulated STAT3 dimers

... de STAT3 e, por conseguinte, a sua ...do STAT3 ao ...ativar STAT3 para a sua função ...de STAT3, SH2 e ...de STAT3 em dois plasmídeos independentes. Quando duas moléculas de ... See full document

58

Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms

Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms

... turnover on cells, and in an attempt to determine possible PTM’s in STEAP1 protein, in silico analysis was carried ...types of PTM’s were found to be likely to occur in STEAP1 protein, namely ... See full document

10

Identification and characterization of HTLV-1 HBZ post-translational modifications.

Identification and characterization of HTLV-1 HBZ post-translational modifications.

... In the current study, we decided to examine the roles of phosphorylation and acetylation individually by mutating modi- fied amino acids to mimetic (SRD and KRQ, respectively) and inhibitory (SRA and ... See full document

10

Histone post-translational modifications and chromatin remodelers in colorectal cancer

Histone post-translational modifications and chromatin remodelers in colorectal cancer

... frequent post-translational modification that occurs both on lysine and arginine residues of the N-terminal tail of ...groups of enzymes, histone methyltransferases ... See full document

25

Managers perceptions about employees acceptance of HR practices and its interactions with modifications in the HR system

Managers perceptions about employees acceptance of HR practices and its interactions with modifications in the HR system

... direct role. The practices are determined by the top management of these 3 cases, such as strategic objectives (Org ...2,3,4). The interference of trust, is strongly conditioned ... See full document

9

On the Relevance of Considering the Intermolecular Interactions on the Prediction of the Vibrational Spectra of Isopropylamine

On the Relevance of Considering the Intermolecular Interactions on the Prediction of the Vibrational Spectra of Isopropylamine

... for the evaluation of the effects of cooperativity on the reliability of the PiMM method [48] for predicting the vibrational frequencies, it was found that ... See full document

13

Expression of histone modifying enzymes and histone post-translational marks in colorectal cancer

Expression of histone modifying enzymes and histone post-translational marks in colorectal cancer

... to the complexity of colon carcinogenesis the clinical outcome of CRC can vary significantly in cases with the same clinic-pathological ...envisage the prognosis and treatment ... See full document

70

THE ROLE OF GLIPTINS ON ADIPOGENESIS

THE ROLE OF GLIPTINS ON ADIPOGENESIS

... from the American type Culture Collection – LGC Promochem (Barcelona, Spain); Visceral and Epididymal Human pre-adipocytes cells and also the Lipolysis Assay Kit were obtained from Zenbio, ... See full document

87

The role of cash on the outsourcing decision

The role of cash on the outsourcing decision

... investigates the effect of cash on a firm’s choice between vertical integration and ...model the production decision in a Principal- Agent framework, and show that what motivates the ... See full document

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