[PDF] Top 20 Therapeutic implications of GIPC1 silencing in cancer.
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Therapeutic implications of GIPC1 silencing in cancer.
... to GIPC1 KD cell ...and GIPC1 KD MDA-MB231 cell lines were cultured in normal L-15 growth media and MDA-MB231 culture conditions on Poly-Prep microscope slides (Sigma ...fixed in 4% ... See full document
11
The therapeutic implications of plasticity of the cancer stem cell phenotype.
... cases of treatment failure due to the evolution of acquired resistance, resistant cells are present at the time of ...prognosis of cancer patients (Fig. 6). First we study the ... See full document
9
Therapeutic implications from sensitivity analysis of tumor angiogenesis models.
... effect of small pa- rameter perturbations about their nominal values, it does not indicate the effect of concurrent, large perturbations in all model ...parameters. In cancer ... See full document
10
RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells
... repair in cancer cells is an important mechanism of therapeutic resistance, and inhibition of DNA repair pathway would be expected to make tumor cells more sensitive to DNA damage ... See full document
11
Identification of genes differentially expressed in breast cancer
... Breast cancer comprises heterogeneous tumors with different clinical characteristics, disease courses, and responses to specific ...accumulation of genetic and epigenetic alterations in epithelial ... See full document
85
Understanding the role of KRAS-regulated autophagy in colorectal cancer: therapeutic implications
... promotion of apoptosis (Luo & Rubinsztein, ...levels of some members of this family and did not find any significant variation upon autophagy induction by starvation in both HCT116 ... See full document
115
The rescue of miR-148a expression in pancreatic cancer: an inappropriate therapeutic tool.
... cause of death by cancer in Western countries whereas it represents only 3% of new cases each year ...lack of early specific diagnostic markers and by the absence of efficient ... See full document
10
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
... Previously in phase II trial, CPX-351 had already showed a survival benefits and the data on over survival could be expected in the first quarter of 2016 (Lancet et ...formulation of Celator ... See full document
10
Silencing and un-silencing of tetracycline-controlled genes in neurons.
... apparent in the olfactory bulb and low transactivation in the forebrain by three routes of Dox delivery; water, food and intraperitoneal injection ...shown). In none of our five ... See full document
10
Arq. Bras. Oftalmol. vol.75 número6
... signs of MH in 25 of 29 ...membranes. In MH stages I (2 eyes) and II (1 eye), both transducers were not useful to analyze the macular thickening, but suggestive findings as macular ... See full document
5
TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.
... pFU. In the tamoxifen inducible lentiviral system, the inducible transcriptional activator Gal4 1-147 ER T2 VP16 (GEV16) was cloned into pFU PGK Hygro, and the genes TAK1, TAK1(K63W), IKK2EE, cFlipL, cFlipp43, ... See full document
9
Evaluation of the effect of a therapeutic dose of gamma irradiation on the thermal and structural properties of polycaprolactone/gypsum composite films / Avaliação do efeito da irradiação gamma em dose terapêutica nas propriedades térmicas e estruturais em filmes do compósito policaprolactona/gesso
... effect of a therapeutic dose of gamma irradiation used, for example, in cancer treatment, on the thermal and structural properties of polycaprolactone/gypsum composite films ... See full document
13
Regulação epigenética no envelhecimento e no câncer gástrico
... evaluated in 158 and 131 samples of gastric tissue, ...ng) of gastric tissue samples underwent bisulfite modification using EpiTect Bisulfite kit (Qiagen, Germany) according to the manufacturer’s ... See full document
109
Investigating The Use Of Mobile Computing In Zimbabwe Polytechnics Case Of A Polytechnic In Zimbabwe
... INTRODUCTION In the period prior to 2003 Polytechnics in Zimbabwe had a mix of Information Communication Technologies (ICTs), varying from one institution to the ...invested in, so while some ... See full document
5
Extract of Azadirachta indica (Neem) Leaf Induces Apoptosis in 4T1 Breast Cancer BALB/c Mice
... capable of de- tecting apoptosis in intact tissue specimens ...tion of DNA fragmentation in situ, by end labeling of DNA strand breaks using terminal deoxyribonu- cleotidyl transferase ... See full document
10
Int. braz j urol. vol.36 número3
... issue of the International Braz J Urol presents original contributions and editorials from many different countries, such as USA, Germany, France, Greece, Canada, Bra- zil, Spain, Italy, Korea, Iran, Belgium, ... See full document
2
Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.
... ability of RNases correlates with their net positive charge ...charge of barnase (pI ,9) [34] aids its binding to the negatively charged cell ...observed in cells stained with barnase, indicating ... See full document
13
Epigenetic silencing of miR-338-3p contributes to tumorigenicity in gastric cancer by targeting SSX2IP.
... mechanism of miRNAs expression in tumorigenesis is still unclear, epigenetic regulation has been suggested to play an important role ...mainly in the CpG island commonly located in the ... See full document
13
Exploring the chemotherapeutic potential of Brassicaceae extracts in colorectal cancer cell spheroids
... made in low-serum culture medium (RPMI medium with ...only in low-serum culture medium and in medium with the maximum %v/v of the solvent in which the extract/ITCs were dissolved, were ... See full document
98
Editor’s Pick: PSMA-Specific Ligands in Prostate Cancer Diagnosis and Therapy
... antigen of prostate cancer. It is overexpressed in almost all prostate cancers, and the expression level increases with prostate cancer ...expressed in the neovasculature of ... See full document
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